Compile Data Set for Download or QSAR
Report error Found 77 Enz. Inhib. hit(s) with all data for entry = 8178
TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235762BDBM235762(US9359371, 46)
Affinity DataIC50: 0.310nMpH: 7.5Assay Description:The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (35 μg/mL) in Tris-HCl buffer of pH 7.5. 1 μM cGMP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235742BDBM235742(US9359371, 11)
Affinity DataIC50: 0.410nMpH: 7.5Assay Description:The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (35 μg/mL) in Tris-HCl buffer of pH 7.5. 1 μM cGMP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235755BDBM235755(US9359371, 38)
Affinity DataIC50: 0.800nMpH: 7.5Assay Description:The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (35 μg/mL) in Tris-HCl buffer of pH 7.5. 1 μM cGMP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235735BDBM235735(US9359371, 3)
Affinity DataIC50: 0.910nMpH: 7.5Assay Description:The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (35 μg/mL) in Tris-HCl buffer of pH 7.5. 1 μM cGMP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235742BDBM235742(US9359371, 11)
Affinity DataIC50: 1.31nMpH: 7.5Assay Description:The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (35 μg/mL) in Tris-HCl buffer of pH 7.5. 1 μM cGMP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235734BDBM235734(US9359371, 2)
Affinity DataIC50: 2.12nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235742BDBM235742(US9359371, 11)
Affinity DataIC50: 4.02nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235738BDBM235738(US9359371, 6)
Affinity DataIC50: 4.25nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235736BDBM235736(US9359371, 4)
Affinity DataIC50: 4.63nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235750BDBM235750(US9359371, 32)
Affinity DataIC50: 4.63nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235733BDBM235733(US9359371, 1)
Affinity DataIC50: 6.04nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235733BDBM235733(US9359371, 1)
Affinity DataIC50: 6.04nMpH: 7.5Assay Description:The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (35 μg/mL) in Tris-HCl buffer of pH 7.5. 1 μM cGMP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 6.99nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235765BDBM235765(US9359371, 50)
Affinity DataIC50: 7.72nMpH: 7.5Assay Description:The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (35 μg/mL) in Tris-HCl buffer of pH 7.5. 1 μM cGMP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235764BDBM235764(US9359371, 48)
Affinity DataIC50: 7.99nMpH: 7.5Assay Description:The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (35 μg/mL) in Tris-HCl buffer of pH 7.5. 1 μM cGMP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 8.56nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 235735BDBM235735(US9359371, 3)
Affinity DataIC50: 8.89nMpH: 7.5Assay Description:Method: The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (0.2 μg/mL) in Tris-HCl buffer of pH 7.5. 100 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 9.29nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235748BDBM235748(US9359371, 27)
Affinity DataIC50: 10.4nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 10.8nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 10.8nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 10.8nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 10.8nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 10.8nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235757BDBM235757(US9359371, 40)
Affinity DataIC50: 11.9nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 12.3nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 12.5nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235735BDBM235735(US9359371, 3)
Affinity DataIC50: 12.9nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235740BDBM235740(US9359371, 8)
Affinity DataIC50: 13.2nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235762BDBM235762(US9359371, 46)
Affinity DataIC50: 14.9nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235760BDBM235760(US9359371, 43)
Affinity DataIC50: 15.4nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235746BDBM235746(US9359371, 21)
Affinity DataIC50: 17.3nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 17.3nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 17.3nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 17.3nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 17.3nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 17.3nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 17.3nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 17.3nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235737BDBM235737(US9359371, 5)
Affinity DataIC50: 17.4nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 20.9nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 20.9nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 20.9nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 20.9nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235756BDBM235756(US9359371, 39)
Affinity DataIC50: 21.4nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235749BDBM235749(US9359371, 28)
Affinity DataIC50: 22.6nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235758BDBM235758(US9359371, 41)
Affinity DataIC50: 22.9nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235741BDBM235741(US9359371, 9)
Affinity DataIC50: 23.2nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 26.0nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 235766BDBM235766(US9359371, Avanafil)
Affinity DataIC50: 26.0nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

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