Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 1103
TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223288BDBM223288((1S,2S)-2-[(5-{(2-Fluoro-2-methylpropyl)[2-fluoro-...)
Affinity DataIC50: 0.248nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223287BDBM223287((1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(2-flu...)
Affinity DataIC50: 0.289nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 310035BDBM310035(US9657001, 64 | (1S,2S)-2-({5-[(5-Chloro-2,4-diflu...)
Affinity DataIC50: 0.483nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223290BDBM223290((1S,2S)-2-[(5-{[2-Fluoro-5-(trifluoromethyl)phenyl...)
Affinity DataIC50: 0.658nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223261BDBM223261(2-(5-((Cyclopropylmethyl)(1,2-dihydroacenaphthylen...)
Affinity DataIC50: 9nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223281BDBM223281(2-(5-((Cyclopropylmethyl)(naphthalen-1-yl)amino)-4...)
Affinity DataIC50: 17nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223232BDBM223232(2-(5-((Cyclopropylmethyl)(4-fluoronaphthalen-1-yl)...)
Affinity DataIC50: 18nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223284BDBM223284(2-(5-((Cyclopropylmethyl)(4-methylnaphthalen-1-yl)...)
Affinity DataIC50: 18nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223226BDBM223226(2-(5-((4-Chloronaphthalen-1-yl)(cyclopropylmethyl)...)
Affinity DataIC50: 18nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223283BDBM223283(2-(5-((Cyclopropylmethyl)(4-fluoronaphthalen-1-yl)...)
Affinity DataIC50: 19nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 310005BDBM310005(US9657001, 34 | 2-(5-((Cyclopropylmethyl)(4-(trifl...)
Affinity DataIC50: 19nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223239BDBM223239(2-(5-((Cyclopropylmethyl)(4-methylbenzyl)amino)-3-...)
Affinity DataIC50: 22nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223234BDBM223234(2-(5-((Cyclopropylmethyl)(naphthalen-1-yl)amino)-3...)
Affinity DataIC50: 24nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223262BDBM223262(2-(5-((Cyclopropylmethyl)(5-(trifluoromethyl)napht...)
Affinity DataIC50: 25nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223271BDBM223271(2-(4-((Cyclopropylmethyl)(4-fluoronaphthalen-1-yl)...)
Affinity DataIC50: 26nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223237BDBM223237(2-(5-((Cyclopropylmethyl)(naphthalen-2-yl)amino)-3...)
Affinity DataIC50: 28nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223263BDBM223263(2-(5-((Cyclopropylmethyl)(1,2-dihydroacenaphthylen...)
Affinity DataIC50: 31nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 309984BDBM309984(US9657001, 13 | 2-(5-((4-Chlorobenzyl)(cyclopropyl...)
Affinity DataIC50: 34nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223242BDBM223242(2-(5-((Cyclopropylmethyl)(naphthalen-2-ylmethyl)am...)
Affinity DataIC50: 34nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223236BDBM223236(2-(5-((Cyclopropylmethyl)(4-methylnaphthalen-1-yl)...)
Affinity DataIC50: 35nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223230BDBM223230(2-(5-((4-Chlorophenyl)((1-methylcyclopropyl)methyl...)
Affinity DataIC50: 38nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223286BDBM223286((2-(1H-Tetrazol-5-yl)cyclopropyl)(5-((cyclopropylm...)
Affinity DataIC50: 39nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223243BDBM223243(2-(5-((3-Chlorobenzyl)(cyclopropylmethyl)amino)-3-...)
Affinity DataIC50: 39nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223273BDBM223273(2-(4-((Cyclopropylmethyl)(naphthalen-1-yl)amino)-2...)
Affinity DataIC50: 46nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 309977BDBM309977(US9657001, 6)
Affinity DataIC50: 47nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223282BDBM223282(2-(5-((Cyclopropylmethyl)(naphthalen-1-yl)amino)-4...)
Affinity DataIC50: 50nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223246BDBM223246(2-(5-((Cyclopropylmethyl)(2-fluoro-4-(trifluoromet...)
Affinity DataIC50: 53nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223269BDBM223269(2-(6-(Cyclopropylmethyl)(4-methylnaphthalen-1-yl)a...)
Affinity DataIC50: 56nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223272BDBM223272(2-(4-((4-Chloronaphthalen-1-yl)(cyclopropylmethyl)...)
Affinity DataIC50: 61nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223270BDBM223270(2-(4-((Cyclopropylmethyl)(4-methylnaphthalen-1-yl)...)
Affinity DataIC50: 62nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223274BDBM223274(2-(4-((4-Chlorophenyl)(cyclopropylmethyl)amino)-2-...)
Affinity DataIC50: 65nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223250BDBM223250(2-(5-((Cyclopropylmethyl)(naphthalen-1-ylmethyl)am...)
Affinity DataIC50: 66nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223253BDBM223253(2-(5-((Cyclopropylmethyl)(2,3-dimethylbenzyl)amino...)
Affinity DataIC50: 67nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223264BDBM223264(2-(5-((4-Chlorophenyl)(cyclopropylmethyl)amino)-3-...)
Affinity DataIC50: 68nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223276BDBM223276(2-(4-((4-Chlorobenzyl)(cyclopropylmethyl)amino)-2-...)
Affinity DataIC50: 68nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223268BDBM223268(2-(5-((4-Chlorophenyl)(cyclopropylmethyl)amino)-3-...)
Affinity DataIC50: 74nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223275BDBM223275(2-(4-((Cyclopropylmethyl)(3,4-dimethylphenyl)amino...)
Affinity DataIC50: 75nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223266BDBM223266(2-(5-((4-Chlorophenyl)(cyclopropylmethyl)amino)-3-...)
Affinity DataIC50: 81nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223227BDBM223227(2-(5-((4-Chlorophenyl)(cyclopropylmethyl)amino)-3-...)
Affinity DataIC50: 86nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223245BDBM223245(2-(5-((Cyclopropylmethyl)(2-methyl-3-(trifluoromet...)
Affinity DataIC50: 88nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223285BDBM223285((2-(1H-Tetrazol-5-yl)cyclopropyl)(5-((cyclopropylm...)
Affinity DataIC50: 96nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223244BDBM223244(2-(5-((Cyclopropylmethyl)(4-fluorobenzyl)amino)-3-...)
Affinity DataIC50: 105nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223247BDBM223247(2-(5-((2-Chloro-3-(trifluoromethyl)benzyl)(cyclopr...)
Affinity DataIC50: 112nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 309974BDBM309974(US9657001, 3)
Affinity DataIC50: 149nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223255BDBM223255(2-(5-((3-Chloro-2,4-difluorobenzyl)(cyclopropylmet...)
Affinity DataIC50: 152nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223278BDBM223278(2-(4-((Cyclopropylmethyl)(5-(trifluoromethyl)quino...)
Affinity DataIC50: 152nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223240BDBM223240(2-(5-((Cyclopropylmethyl)(3-methylbenzyl)amino)-3-...)
Affinity DataIC50: 171nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223258BDBM223258(2-(5-((Cyclopropylmethyl)(2,3-difluoro-4-methylben...)
Affinity DataIC50: 185nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 223260BDBM223260(2-(5-((Cyclopropylmethyl)(5-(trifluoromethyl)quino...)
Affinity DataIC50: 229nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 309975BDBM309975(US9657001, 4)
Affinity DataIC50: 263nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

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