Compile Data Set for Download or QSAR
Report error Found 31 of affinity data for UniProtKB/TrEMBL: Q9ULZ9
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062351BDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of MMP17 catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035507BDBM50035507(CHEMBL3355722)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human recombinant ADAM17 using Mca-PLAQAV-Dpa-RSSSR-NH2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035475BDBM50035475(CHEMBL3355723)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant ADAM17 using Mca-PLAQAV-Dpa-RSSSR-NH2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146471BDBM50146471(N-{1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-2-[4-(2-methyl...)
Affinity DataIC50: 220nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146480BDBM50146480(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylmethyl)-2...)
Affinity DataIC50: 330nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146467BDBM50146467(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 350nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146478BDBM50146478(N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylmethyl)-2...)
Affinity DataIC50: 350nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146479BDBM50146479(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexyl)-2-[4-(2...)
Affinity DataIC50: 500nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146473BDBM50146473(2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-a...)
Affinity DataIC50: 550nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146469BDBM50146469(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 600nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146474BDBM50146474(N-{2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-1-[4-(2-methyl...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146470BDBM50146470(N-Hydroxy-N-{1-(4-methylene-cyclohexyl)-2-[4-(2-me...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146468BDBM50146468(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146477BDBM50146477(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146476BDBM50146476(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylidenemeth...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035472BDBM50035472(CHEMBL3355724)
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of human recombinant ADAM17 using Mca-PLAQAV-Dpa-RSSSR-NH2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146475BDBM50146475(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146472BDBM50146472(N-hydroxy-N-(1-(1-isobutylpiperidin-4-ylidene)-3-(...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 400682BDBM400682(US10000476, Compound I-41)
Affinity DataIC50: 1.60E+4nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 400650BDBM400650(US10000476, Compound I-9)
Affinity DataIC50: 2.10E+4nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 400727BDBM400727(US10000476, Compound I-86)
Affinity DataIC50: 2.70E+4nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50234334BDBM50234334(benzyl 6-benzyl-5,7-dioxo-6,7-dihydro-5H-thiazolo[...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MMP17 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 400681BDBM400681(US10000476, Compound I-40)
Affinity DataIC50: 3.00E+4nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265079BDBM50265079(CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MMP17 catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265079BDBM50265079(CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MMP17 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 400703BDBM400703(US10000476, Compound I-62)
Affinity DataIC50: 4.50E+4nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 400668BDBM400668(US10000476, Compound I-27)
Affinity DataIC50: 5.70E+4nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 400699BDBM400699(US10000476, Compound I-64 | US10000476, Compound I...)
Affinity DataIC50: 1.00E+5nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 400651BDBM400651(US10000476, Compound I-153 | US10000476, Compound ...)
Affinity DataIC50: 1.00E+5nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50234334BDBM50234334(benzyl 6-benzyl-5,7-dioxo-6,7-dihydro-5H-thiazolo[...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP17 catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 400231BDBM400231(US10000476, Compound I-1 | US10000476, Compound I-...)
Affinity DataIC50: 1.00E+5nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent