Affinity DataKi: 0.810nMAssay Description:Inhibition of 5-HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 86nMAssay Description:Inhibition of 5-HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.04E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.14E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.92E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.75E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Ability to displace [3H]-oxotremorine from Muscarinic acetylcholine receptor M1 expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:The compound was tested for its binding affinity against M1 human recombinant muscarinic receptor in CHO cells.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Institute of Science and Technology
Curated by ChEMBL
Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:The compound was tested for its binding affinity against nicotinic receptor in synaptic membrane fractions from rat cerebral cortices.More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 11.1nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11.8nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Institute of Science and Technology
Curated by ChEMBL
Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Compound was tested for its binding affinity against nicotinic receptor in synaptic membrane fractions from rat cerebral cortices.More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14.3nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Institute of Science and Technology
Curated by ChEMBL
Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Compound was tested for its binding affinity against nicotinic receptor in synaptic membrane fractions from rat cerebral cortices.More data for this Ligand-Target Pair
Affinity DataIC50: 20.9nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22.9nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Ability to displace [3H]-oxotremorine from Muscarinic acetylcholine receptor M1 expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataIC50: 25.8nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35.9nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Ability to displace [3H]-N-methylscopolamine from Muscarinic acetylcholine receptor M1 expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataIC50: 46.2nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 53.6nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Ability to displace [3H]-oxotremorine from Muscarinic acetylcholine receptor M1 expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 61.7nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 67.1nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Ability to displace [3H]-oxotremorine from Muscarinic acetylcholine receptor M1 expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair