Affinity DataKi: 5nMAssay Description:Reversible inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrateMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant CK2alpha by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant CK2alpha at enzyme-substrate complex by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research
Curated by ChEMBL
Celgene Quanticel Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of BRD4-BD1 in human Raji cells assessed as downregulation of MYC gene expression by PCR methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research
Curated by ChEMBL
Celgene Quanticel Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of BRD4-BD1 in human Raji cells assessed as downregulation of MYC gene expression by PCR methodMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research
Curated by ChEMBL
Celgene Quanticel Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research
Curated by ChEMBL
Celgene Quanticel Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research
Curated by ChEMBL
Celgene Quanticel Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Jecure Therapeutics
Curated by ChEMBL
Jecure Therapeutics
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS and nigericin-stimulated human PBMC cells assessed as reduction in IL-1beta release preincubated w...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair