Affinity DataKi: 207nMAssay Description:Binding affinity of the compound towards immunophilin cytosolic protein FK506 binding protein 12 was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Binding affinity of the compound towards immunophilin cytosolic protein FK506 binding protein 12 was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of COX1-mediated platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 125nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition at rat aldose reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition at recombinant human CYP2C19More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition at rat serotonin transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition at recombinant human CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition at CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 790nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.30E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.90E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 500nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 790nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 630nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 630nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.90E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 390nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 630nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.90E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair