54 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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A structural insight into the P1S1 binding mode of diaminoethylphosphonic and phosphinic acids, selective inhibitors of alanine aminopeptidases.
Wroclaw University Of Technology
Novel leucine ureido derivatives as aminopeptidase N inhibitors. Design, synthesis and activity evaluation.
Fudan University
Influence of polar side chains modifications on the dual enkephalinase inhibitory activity and conformation of human opiorphin, a pain perception related peptide.
Institute Of Advanced Chemistry Of Catalonia (Iqac-Csic)
Modulation of disulfide dual ENKephalinase inhibitors (DENKIs) activity by a transient N-protection for pain alleviation by oral route.
Pharmaleads
Exploring S1 plasticity and probing S1' subsite of mammalian aminopeptidase N/CD13 with highly potent and selective aminobenzosuberone inhibitors.
Universit£
Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases.
University Of Athens
New orally active dual enkephalinase inhibitors (DENKIs) for central and peripheral pain treatment.
Pharmaleads
Novelß-dicarbonyl derivatives as inhibitors of aminopeptidase N (APN).
Shandong University
Solid phase synthesis and biological evaluation of probestin as an angiogenesis inhibitor.
The University Of Oklahoma Health Sciences Center
Discovery of a synthetic Aminopeptidase N inhibitor LB-4b as a potential anticancer agent.
Shandong University
Novel indoline-2,3-dione derivatives as inhibitors of aminopeptidase N (APN).
Shandong University
Selective aminopeptidase-N (CD13) inhibitors with relevance to cancer chemotherapy.
Universit£
Novel leucine ureido derivatives as inhibitors of aminopeptidase N (APN).
Shandong University
The replacement of His(4) in angiotensin IV by conformationally constrained residues provides highly potent and selective analogues.
Vrije Universiteit Brussel
Development of Synthetic Aminopeptidase N/CD13 Inhibitors to Overcome Cancer Metastasis and Angiogenesis.
TBA
Rapid and efficient synthesis of a novel series of substituted aminobenzosuberone derivatives as potent, selective, non-peptidic neutral aminopeptidase inhibitors.
Universit£
Remarkable potential of thea-aminophosphonate/phosphinate structural motif in medicinal chemistry.
Wroclaw University Of Technology
Design, synthesis and biological evaluation of novel amino acid ureido derivatives as aminopeptidase N/CD13 inhibitors.
Shandong University
Proposed Bioactive Conformations of Opiorphin, an Endogenous Dual APN/NEP Inhibitor.
TBA
Structure-activity relationship study of opiorphin, a human dual ectopeptidase inhibitor with antinociceptive properties.
Institute Of Advanced Chemistry Of Catalonia (Iqac-Csic)
Inhibitors of bacterial N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) and demonstration of in vitro antimicrobial activity.
Loyola University
Synthesis, biological evaluation and structural determination of beta-aminoacyl-containing cyclic hydrazine derivatives as dipeptidyl peptidase IV (DPP-IV) inhibitors.
Korea Research Institute Of Chemical Technology
N-hydroxy-2-(naphthalene-2-ylsulfanyl)-acetamide, a novel hydroxamic acid-based inhibitor of aminopeptidase N and its anti-angiogenic activity.
Sejong University
Long lasting antinociceptive properties of enkephalin degrading enzyme (NEP and APN) inhibitor prodrugs.
University Of Paris
Investigation of the active site of aminopeptidase A using a series of new thiol-containing inhibitors.
University Of Paris
Design, synthesis and antimalarial activity of novel, quinoline-based, zinc metallo-aminopeptidase inhibitors.
Universit£
Nonpeptide small-molecular inhibitors of dipeptidyl peptidase IV: N-phenylphthalimide analogs.
University Of Tokyo
Pseudopeptide inhibitors of aminopeptidases containing the [CH(CN)NH] surrogate as a transition-state MIMIC
TBA
Design, synthesis and biological evaluation of novel 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as aminopeptidase N/CD13 inhibitors.
Shandong University
Novel aminopeptidase N (APN/CD13) inhibitors derived from chloramphenicol amine.
Shandong University
Potent macrocyclic inhibitors of insulin-regulated aminopeptidase (IRAP) by olefin ring-closing metathesis.
Uppsala University
Discovery ofß-aminoacyl containing thiazolidine derivatives as potent and selective dipeptidyl peptidase IV inhibitors.
Korea Research Institute Of Chemical Technology
Amino-benzosuberone: a novel warhead for selective inhibition of human aminopeptidase-N/CD13.
Merck Sharpe And Dohme
Disulfide cyclized tripeptide analogues of angiotensin IV as potent and selective inhibitors of insulin-regulated aminopeptidase (IRAP).
Uppsala University
Novel cyclic-imide peptidomimetics as aminopeptidase N inhibitors. Structure-based design, chemistry and activity evaluation. II.
Shandong University
New aromatic monoesters of alpha-aminoaralkylphosphonic acids as inhibitors of aminopeptidase N/CD13.
Wroclaw University Of Technology
Synthesis of new sulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors.
Shandong University
Ligands to the (IRAP)/AT4 receptor encompassing a 4-hydroxydiphenylmethane scaffold replacing Tyr2.
Uppsala University
Design, synthesis and evaluation of novel sulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors.
Shandong University
Design, synthesis and preliminary evaluation of novel pyrrolidine derivatives as matrix metalloproteinase inhibitors.
Shandong University
Novel hydroxamic acid-related phosphinates: inhibition of neutral aminopeptidase N (APN).
Wroclaw University Of Technology
Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions.
Monash University
Structure-activity relationship of diaryl phosphonate esters as potent irreversible dipeptidyl peptidase IV inhibitors.
University Of Antwerp (Uia)
Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases.
Monash University
Leucine ureido derivatives as aminopeptidase N inhibitors using click chemistry. Part II.
Shandong University
Novel potent nonpeptide aminopeptidase N inhibitors with a cyclic imide skeleton.
University Of Tokyo
Synthesis and biological characterization of ubenimex-fluorouracil conjugates for anti-cancer therapy.
Shandong University
Puromycin based inhibitors of aminopeptidases for the potential treatment of hematologic malignancies.
University Of Minnesota
Novel leucine ureido derivatives as aminopeptidase N inhibitors using click chemistry.
Shandong University