Found 11 hits for monomerid = 50149238 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50149238
(4-Hydroxybiphenyl | 4-Phenylphenol | 4-biphenylol ...)Show InChI InChI=1S/C12H10O/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar
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CHEBI CHEMBL KEGG PC cid PC sid UniChem
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Similars
| Article PubMed
| 1.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Agri Ibrahim Cecen University
| Assay Description Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate. |
J Enzyme Inhib Med Chem 27: 880-5 (2012)
Article DOI: 10.3109/14756366.2011.637202 BindingDB Entry DOI: 10.7270/Q2VH5MRR |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50149238
(4-Hydroxybiphenyl | 4-Phenylphenol | 4-biphenylol ...)Show InChI InChI=1S/C12H10O/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar
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CHEBI CHEMBL KEGG PC cid PC sid UniChem
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Similars
| Article PubMed
| 7.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Agri Ibrahim Cecen University
| Assay Description Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate. |
J Enzyme Inhib Med Chem 27: 880-5 (2012)
Article DOI: 10.3109/14756366.2011.637202 BindingDB Entry DOI: 10.7270/Q2VH5MRR |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Homo sapiens (Human)) | BDBM50149238
(4-Hydroxybiphenyl | 4-Phenylphenol | 4-biphenylol ...)Show InChI InChI=1S/C12H10O/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar
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CHEBI CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Agri Ibrahim Cecen University
| Assay Description Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate. |
J Enzyme Inhib Med Chem 27: 880-5 (2012)
Article DOI: 10.3109/14756366.2011.637202 BindingDB Entry DOI: 10.7270/Q2VH5MRR |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 6 (CA-VI)
(Homo sapiens (Human)) | BDBM50149238
(4-Hydroxybiphenyl | 4-Phenylphenol | 4-biphenylol ...)Show InChI InChI=1S/C12H10O/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13H | PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar
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CHEBI CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 8.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Agri Ibrahim Cecen University
| Assay Description Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate. |
J Enzyme Inhib Med Chem 27: 880-5 (2012)
Article DOI: 10.3109/14756366.2011.637202 BindingDB Entry DOI: 10.7270/Q2VH5MRR |
More data for this Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50149238
(4-Hydroxybiphenyl | 4-Phenylphenol | 4-biphenylol ...)Show InChI InChI=1S/C12H10O/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar
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CHEBI CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 2.80E+5 | n/a | n/a | n/a | n/a | n/a |
Sunesis Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Dissociation constant for Matrix Metalloprotease-3 (MMP-3) |
J Med Chem 47: 3463-82 (2004)
Article DOI: 10.1021/jm040031v BindingDB Entry DOI: 10.7270/Q2NC61ZJ |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase (2 and 3)
(Homo sapiens (Human)) | BDBM50149238
(4-Hydroxybiphenyl | 4-Phenylphenol | 4-biphenylol ...)Show InChI InChI=1S/C12H10O/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar
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CHEBI CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | 2.80E+5 | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lyon
Curated by ChEMBL
| Assay Description Binding affinity to human MMP3 catalytic domain (81 to 256 residues) expressed in Escherichia coli BL21 (DE3) pLysS by 15N-HSQC-NMR spectroscopy |
J Med Chem 63: 11420-11435 (2020)
|
More data for this Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50149238
(4-Hydroxybiphenyl | 4-Phenylphenol | 4-biphenylol ...)Show InChI InChI=1S/C12H10O/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar
| Purchase
CHEBI CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Basel
Curated by ChEMBL
| Assay Description Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881) |
J Med Chem 48: 5666-74 (2005)
Article DOI: 10.1021/jm050403f BindingDB Entry DOI: 10.7270/Q2TM7CBZ |
More data for this Ligand-Target Pair | |
Protein-tyrosine phosphatase 1B
(Homo sapiens (Human)) | BDBM50149238
(4-Hydroxybiphenyl | 4-Phenylphenol | 4-biphenylol ...)Show InChI InChI=1S/C12H10O/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar
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CHEBI CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.17E+9 | n/a | n/a | n/a | n/a | n/a | n/a |
Leadscope, Inc.
Curated by ChEMBL
| Assay Description Inhibitory activity determined against Protein tyrosine phosphatase PTB1B |
J Med Chem 46: 4770-5 (2003)
Article DOI: 10.1021/jm0302703 BindingDB Entry DOI: 10.7270/Q2HD7WV1 |
More data for this Ligand-Target Pair | |
Serum albumin
(Homo sapiens (Human)) | BDBM50149238
(4-Hydroxybiphenyl | 4-Phenylphenol | 4-biphenylol ...)Show InChI InChI=1S/C12H10O/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar
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CHEBI CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 9.55E+12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Molecular Discovery Ltd.
Curated by ChEMBL
| Assay Description Binding affinity towards human serum albumin |
J Med Chem 48: 2469-79 (2005)
Article DOI: 10.1021/jm049227l BindingDB Entry DOI: 10.7270/Q2125WDN |
More data for this Ligand-Target Pair | |
Bcl-xL/Bcl-2-binding component 3
(Homo sapiens (Human)) | BDBM50149238
(4-Hydroxybiphenyl | 4-Phenylphenol | 4-biphenylol ...)Show InChI InChI=1S/C12H10O/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 6.00E+6 | n/a | n/a | n/a | n/a | n/a |
Taros Chemicals GmbH & Co. KG
Curated by ChEMBL
| Assay Description Binding affinity to BCL-XL (unknown origin) by 15N HSQC NMR analysis |
Eur J Med Chem 167: 76-95 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.084 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50149238
(4-Hydroxybiphenyl | 4-Phenylphenol | 4-biphenylol ...)Show InChI InChI=1S/C12H10O/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | >5.00E+6 | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Dissociation constant against VEGF (vascular endothelial growth factor) was determined. |
J Med Chem 43: 3443-7 (2000)
Article DOI: 10.1021/jm000164q BindingDB Entry DOI: 10.7270/Q2X068B2 |
More data for this Ligand-Target Pair | |