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Patent
Data
Cmpds
UniProt
HGNC*
Patent Title
Organization
Deposition
Downloads
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165
2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX3CR1
ASTRAZENECA AB
09/24/24
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158
4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZINES AND PREPARATION AND USES THEREOF
Biosplice Therapeutics, Inc.
09/24/24
-
29
APPLICATIONS OF BIASED LIGANDS OF THE SEROTONIN 5-HT7 RECEPTOR FOR THE TREATMENT OF PAIN, MULTIPLE SCLEROSIS AND THE CONTROL OF THERMOREGULATION
Centre National de la Recherche Scientifique; Université d''Orléans
09/24/24
-
5
BICYCLIC COMPOUNDS AS ALLOSTERIC SHP2 INHIBITORS
Revolution Medicines, Inc.
09/24/24
-
8
BICYCLIC HETEROCYCLIC FGFR4 INHIBITOR, PHARMACEUTICAL COMPOSITION AND PREPARATION COMPRISING SAME, AND APPLICATION THEREOF
Hangzhou Apeloa Medicine Research Institute Co., Ltd.; Apeloa Pharmaceutical Co., Ltd.
09/24/24
-
3
DEUTERATED DHODH INHIBITORS
IMMUNIC AG
09/24/24
-
16
Fused Ring Derivatives Useful as KRAS G12D Inhibitors
JACOBIO PHARMACEUTICALS CO., LTD.
09/24/24
-
6
GLYCOSYLTRANSFERASE INHIBITORS
CALIFORNIA INSTITUTE OF TECHNOLOGY; UNIVERSITY OF TENNESSEE FRESEARCH FOUNDATION
09/24/24
-
29
IMIDAZO[1,2-B]PYRIDAZINE BASED TRICYCLIC COMPOUNDS AS INHIBITORS OF HASPIN AND THERAPEUTIC USES THEREOF
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS
09/24/24
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17
INHIBITORS OF DYRK AND PIM
COLD SPRING HARBOR LABORATORY; VICHEM CHEMIE RESEARCH, LTD.; THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
09/24/24
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4
METHODS AND COMPOSITIONS COMPRISING A BRAF INHIBITOR AND A PD-1 BINDING ANTAGONIST
Hoffmann-La Roche Inc.
09/24/24
-
5
NOVEL CYCLOPENTA[C]PYRROL NEGATIVE ALLOSTERIC MODULATORS OF NR2B
Novartis AG; Cadent Therapeutics, Inc.
09/24/24
-
45
NOVEL N-ACYL-[3-SUBSTITUTED]-[8-SUBSTITUTED]-5,6-DIHYDRO-[1,2,4]TRIAZOLO[4,3-a]PYRAZINES AS SELECTIVE NK-3 RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR USE IN NK-3 RECEPTOR-MEDIATED DISORDERS
Ogeda SA
09/24/24
-
10
SHP2-Targeting Small Molecules For Use As Anti-Cancer Agents
West Virginia University Board of Governors on behalf of West Virginia University
09/24/24
-
302
SMALL MOLECULAR INHIBITORS OF NF-kB INDUCING KINASE
Janssen Pharmaceutica NV
09/24/24
-
2
TETRAHYDROTHIENO PYRIDINE DERIVATIVES AS DDRS INHIBITORS
CHIESI FARMACEUTICI S.P.A.
09/24/24
-
88
THIOPHENE COMPOUND AND APPLICATION THEREOF
MEDSHINE DISCOVERY INC.
09/24/24
-
17
Alpha-synuclein ligands
Washington University
09/19/24
-
23
Mofezolac derivatives as multi-functions selective COX-1 inhibitors
ITEL Telecomunicazioni S.r.l.
09/19/24
-
1074
N-substituted indole derivatives as PGE2 receptor modulators
IDORSIA PHARMACEUTICALS LTD
09/19/24
-
277
Small molecule DCN1 inhibitors and therapeutic methods using the same
REGENTS OF THE UNIVERSITY OF MICHIGAN
09/19/24
-
1
A Crystal Form of a Fluorine-substituted Pyridopyrazole Compound and a Preparation Method Thereof
JUMBO DRUG BANK CO., LTD
09/18/24
-
27
COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS
UNIVERSITAT DE BARCELONA
09/18/24
-
13
FUSED CYCLIC COMPOUND AS WEE-1 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF
WIGEN BIOMEDICINE TECHNOLOGY (SHANGHAI) CO., LTD.
09/18/24
-
52
INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE
BRISTOL-MYERS SQUIBB COMPANY
09/18/24
-
64
MACROCYCLE COMPLEMENT FACTOR B INHIBITORS
Alexion Pharmaceuticals, Inc.
09/18/24
-
42
MACROCYCLES AND THEIR USE
BLOSSOMHILL THERAPEUTICS, INC.
09/18/24
-
176
NOVEL SUBSTITUTED PYRAZINE-CARBOXAMIDE DERIVATIVES
Boehringer Ingelheim International GmbH
09/18/24
-
53
Pyrazole-containing macrophage migration inhibitory factor inhibitors
YALE UNIVERSITY
09/09/24
-
549
Substituted aminoquinolones as DGKalpha inhibitors for immune activation
BAYER AKTIENGESELLSCHAFT; BAYER PHARMA AKTIENGESELLSCHAFT; DEUTSCHES KREBSFORSCHUNGSZENTRUM
09/09/24
-
141
Vesicular monoamine transporter-2 ligands and their use in the treatment of psychostimulant abuse
University of Kentucky Research Foundation
09/09/24
-
20
1,2,5-Oxadiazoles As Inhibitors Of Indoleamine 2,3- Dioxygenase
Incyte Corporation; Incyte Holdings Corporation
09/05/24
-
182
2,8-DIAZASPIRO[4.5]DECANE COMPOUNDS
Genentech, Inc.
09/05/24
-
19
8-(PICOLINAMIDE) SUBSTITUTED COUMARIN COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF
LONGIVITRON (SUZHOU) BIOTECHNOLOGY CO., LTD
09/05/24
-
240
ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; VANDERBILT UNIVERSITY
09/05/24
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1
CRYSTALLINE FORMS OF (4S)-24-CHLORO-4-ETHYL-73-FLUORO-35-METHOXY-32,5-DIOXO-14-(TRIFLUORO-METHYL)-32H-6-AZA-3(4,1)-PYRIDINA-1(1)-[1,2,3]TRIAZOLA-2(1,2),7(1)-DIBENZENAHEPTAPHANE-74-CARBOXAMIDE
Bayer Aktiengesellschaft
09/05/24
-
17
CULLIN-RING E3 UBIQUITIN LIGASE 4 INHIBITOR COMPOUNDS AND METHODS OF THEIR USE
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
09/05/24
-
170
HETEROAROYL AMIDES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF
Merck Sharp & Dohme LLC
09/05/24
-
4
HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF
Nuclidium AG; University of Basel
09/05/24
-
205
KINASE MODULATORS AND METHODS OF USE THEREOF
NEURON23, INC.
09/05/24
-
5
METHYLQUINAZOLINONE DERIVATIVES
Hoffmann-La Roche Inc.
09/05/24
-
10
Methods and Compositions for Treating Cancer
Ohio Northern University
09/05/24
-
108
NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF
APPLIED PHARMACEUTICAL SCIENCE, INC.
09/05/24
-
15
NOVEL DIOXANE DERIVATIVES
Boehringer Ingelheim International GmbH
09/05/24
-
10
PYRIMIDINE AROMATIC RING COMPOUNDS
Medshine Discovery Inc.
09/05/24
-
486
SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES
Janssen Biotech, Inc.; The Broad Institute, Inc.; The General Hospital Corporation
09/05/24
-
87
Compounds and probes for imaging huntingtin protein
CHDI Foundation, Inc.
08/29/24
-
29
Fused tri-cyclic compound as PDE3/PDE4 dual inhibitor
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
08/29/24
-
28
Preparation for 6-amino-1H-pyrazolo[3,4-d]pyrimidine-based JAK kinase inhibitor and application thereof
INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES & PEKING UNION MEDICAL COLLEGE; CHINA PARMACEUTICAL UNIVERSITY
08/29/24
-
4
Saturated spirocyclics as antiviral agents
Enanta Pharmaceuticals, Inc.
08/29/24
-
22
Use of 2-substituted indazoles for the treatment and prophylaxis of autoimmune diseases
Bayer Pharma Aktiengesellschaft
08/29/24
-
26
Use of JAK1 inhibitors for the treatment of cutaneous lupus erythematosus and Lichen planus (LP)
Incyte Corporation
08/29/24
-
2
COVALENT EGFR INHIBITORS AND METHODS OF USE THEREOF
Dana-Farber Cancer Institute, Inc.
08/27/24
-
2
NUCLEOSIDE ANALOG AND USE THEREOF
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
08/27/24
-
60
1H-PYRROLO[2,3-B]PYRIDINE DERIVATIVES AS BCL-2 INHIBITORS FOR THE TREATMENT OF NEOPLASTIC AND AUTOIMMUNE DISEASES
Newave Pharmaceutical Inc.
08/26/24
-
172
AMINOHETEROARYL KINASE INHIBITORS
Anrui Biomedical Technology (Guangzhou) Co.,Ltd.
08/26/24
-
137
COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THE SAME
Arizona Board of Regents on Behalf of the University of Arizona; The Board of Trustees of the University of Illinois
08/26/24
-
24
FLUORINATED QUINOLINE, QUINOXALINE AND BENZO[B][1,4]OXAZINE DERIVATIVES AS DIHYDROOROTATE DEHYDROGENASE (DHODH) INHIBITORS FOR THE TREATMENT OF CANCER, AUTOIMMUNE AND INFLAMMATORY DISEASES
Janssen Biotech, Inc.
08/26/24
-
16
GALACTOPYRANOSYL-CYCLOHEXYL DERIVATIVES AS E-SELECTIN ANTAGONISTS
GLYCOMIMETICS, INC.
08/26/24
-
10
HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS
CHIESI FARMACEUTICI S.P.A.
08/26/24
-
136
IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND THEIR USE IN THERAPY
Imperial College Innovations Limited; MyricX Pharma Limited
08/26/24
-
44
INHIBITORS OF MYELOPEROXIDASE
ASTRAZENECA AB
08/26/24
-
126
KRAS G12C INHIBITORS
BeiGene Switzerland GmbH
08/26/24
-
98
PHENALKYLAMINES AND METHODS OF MAKING AND USING THE SAME
GILGAMESH PHARMACEUTICALS, INC.
08/26/24
-
17
POTENT AND SELECTIVE COMPOUNDS AS SEROTONIN 1B RECEPTOR MODULATORS
LEUKOS BIOTECH, S.L.; FUNDACIÓ INSTITUT DE RECERCA CONTRA LA LEUCÈMIA JOSEP CARRERAS
08/26/24
-
13
PYRIDOPYRIMIDINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF
Wuhan Humanwell Innovative Drug Research and Development Center Limited Company
08/26/24
-
27
SELECTIVE LIGANDS FOR TAU AGGREGATES
KARIN & STEN MORTSTEDT CBD SOLUTIONS AB
08/26/24
-
6
Dual-functional compounds and methods of use
Biofront Therapeutics (Beijing) Co.
08/22/24
-
592
Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto
Arena Pharmaceuticals
08/22/24
-
75
BET SUBFAMILY INHIBITORS AND METHODS USING SAME
Baylor College of Medicine
08/19/24
-
200
BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS
Janssen Biotech
08/19/24
-
4
FUSED POLYCYCLIC SUBSTITUTED 5-CARBOXYLIC ACID THIENOPYRIMIDINE DIONE COMPOUND AND USE THEREOF
Soter Biopharma
08/19/24
-
94
NEK7 INHIBITORS
Halia Therapeutics
08/19/24
-
25
NOVEL BENZOFURAN, BENZOTHIOPHENE, AND INDOLE ANALOGS THAT INHIBIT THE FORMATION OF TAU OLIGOMERS AND THEIR METHOD OF USE
Oligomerix
08/19/24
-
18
NOVEL QUINAZOLINONES THAT INHIBIT THE FORMATION OF TAU OLIGOMERS AND THEIR METHOD OF USE
Oligomerix
08/19/24
-
162
Nitrogen-Containing Heterocyclic Compound, Pharmaceutical Compositions thereof and Use thereof
280 Bio
08/19/24
-
9
PIPERAZINE DERIVATIVE AND USE THEREOF IN MEDICINE
Chengdu Baiyu Pharmaceutical Co.
08/19/24
-
85
POLYPEPTIDE COMPOUND AND APPLICATION THEREOF
Chengdu Sintanovo Biotechnology Co.
08/19/24
-
157
PYRIMIDINE COMPOUND AS WEE-1 INHIBITOR
Wigen Biomedicine Technology (Shanghai) Co.
08/19/24
-
85
Pyrrolidine Main Protease Inhibitors as Antiviral Agents
Abbvie
08/19/24
-
69
RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF
Boundless Bio
08/19/24
-
10
TRICYCLIC COMPOUND AS HIF2-ALPHA INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Shanghai Jemincare Pharmaceuticals Co.
08/19/24
-
3
β-lactamase inhibitors
Oxford University Innovation
08/13/24
-
11
1,7-naphthyridine derivative and preparation method and use therefor
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang) Co.
08/13/24
-
12
Bicyclic pyrazolyl amines as CDK2 inhibitors
Incyte
08/13/24
-
1
Fluoro-pyridinone phosphates and boronates useful as antibacterial agents
Pfizer
08/13/24
-
3
N-(2-(substituted-naphth-1-yl)ethyl) substituted amide compound, preparation and uses thereof
Beijing Greatway Pharmaceutical Technology Co.
08/13/24
-
20
Substituted cyclopenta[c]pyrroles as ABHD6 antagonists
Ono Pharmaceutical Co.
08/13/24
-
48
Substituted thienopyrroles as PAD4 inhibitors
Bristol-Myers Squibb
08/13/24
-
21
4-AMINOQUINAZOLINE COMPOUND
Astellas Pharma
08/09/24
-
39
BICYCLIC PYRIDINE DERIVATIVE
Sumitomo Pharma Co.
08/09/24
-
31
CYCLIN-DEPENDENT KINASE INHIBITING COMPOUNDS FOR THE TREATMENT OF MEDICAL DISORDERS
G1 Therapeutics
08/09/24
-
20
FUSED RING DERIVATIVES CONTAINING 1,4-OXAZEPANE
Medshine Discovery
08/09/24
-
123
HSD17B13 INHIBITORS AND/OR DEGRADERS
Pfizer
08/09/24
-
2
INHIBITING CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN (CREB) BINDING PROTEIN (CBP)
Formatherapeutics
08/09/24
-
36
INHIBITORS OF CYSTEINE PROTEASES
Texas A&M University
08/09/24
-
36
N-(BENZOYL)-PHENYLALANINE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF
Hangzhou Apeloa Medicine Research Institute Co.
08/09/24
-
67
NITROGEN-CONTAINING SPIRO CYCLIC COMPOUNDS AND PHARMACEUTICAL USE THEREOF
Japan Tobacco
08/09/24
-
15
NOVEL COMPOUNDS COMPRISING A NEW CLASS OF TRANSTHYRETIN LIGANDS FOR TREATMENT OF COMMON AGE-RELATED COMORBIDITIES
Columbia University
08/09/24
-
3
OXA-IBOGAINE ANALOGUES FOR TREATMENT OF SUBSTANCE USE DISORDERS
Columbia University
08/09/24
-
26
PURINES AND METHODS OF THEIR USE
Kineta
08/09/24
-
371
PYRAZOLYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY
Hotspot Therapeutics
08/09/24
-
22
S-CONFIGURATION-CONTAINING AMINO BENZAMIDE PYRIDAZINONE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF
Shanghai Institute Of Materia Medica
08/09/24
-
878
SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS
Les Laboratoires Servier
08/09/24
-
1791
PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND
Chugai Seiyaku Kabushiki Kaisha
08/08/24
-
13
Adenosine receptor activity of methyl/ethyl 3-(substituted benzoyl)-6,8-dimethylindolizine-2-substituted-1-carboxylates
King Faisal University
08/04/24
-
71
Isoindolin-1-on derivative, method for preparing same, and pharmaceutical composition comprising same as effective component for preventing or treating cancer
Korea Research Institute Of Chemical Technology
08/04/24
-
121
Monoacylglycerol lipase modulators for use in autism spectrum disorders
Janssen Pharmaceutica
08/04/24
-
29
HETEROCYCLIC INHIBITORS OF CD73 FOR TREATMENT OF DISEASE
Teon Therapeutics
08/02/24
-
13
INHIBITION OF KDM5A FOR PROMOTING ANTIGEN PRESENTATION, INCREASING CD8+ T CELL INFILTRATION AND BOOSTING ANTI-TUMOR IMMUNE RESPONSE
The Wistar Institute Of Anatomy And Biology
08/02/24
-
16
5,6-DIHYDROTHIENO[3,4-H]QUINAZOLINE COMPOUND
Medshine Discovery
07/25/24
-
8
ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG
Shanghai Institute of Materia Medica, Chinese Academyof Sciences
07/25/24
-
8
HETEROCYCLIC INHIBITORS OF CD73 FOR TREATMENT OF DISEASE
Teon Therapeutics
07/25/24
-
15
INHIBITORS AND DEGRADERS OF JANUS KINASE 2
H. Lee Moffitt Cancer Center and Research Institute
07/25/24
-
1
INHIBITORS OF MENIN-MLL INTERACTION
Biomea Fusion
07/25/24
-
10
METHACRYLAMIDES PROTEIN BINDERS AND USES THEREOF
Yeda Research and Development Co.
07/25/24
-
14
N6-ADENOSINE-METHYLTRANSFERASE INHIBITORS IN CANCER TREATMENT
University of Zurich
07/25/24
-
63
OXOINDOLINE COMPOUND FOR THE TREATMENT OF INFLAMMATORY DISEASES OR CANCER
Hoffmann-La Roche
07/25/24
-
120
PREPARATION OF TETRAHYDROINDAZOLE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS
Merck Sharp & Dohme
07/25/24
-
272
TRICYCLIC COMPOUNDS AND USES THEREOF
Hutchmed
07/25/24
-
35
Compounds and their use
Astrazeneca
07/22/24
-
326
Substituted benzodiazoles and use thereof in therapy
Thomas Helledays Stiftelse FÖR Medicinsk Forskning
07/22/24
-
55
AROMATIC HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF
Gt Apeiron Therapeutics
07/16/24
-
91
BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF
Boehringer Ingelheim Animal Health Usa
07/16/24
-
40
Benzimidazole Derivatives and Their Use As Inhibitors of ITK For The Treatment of Skin Disease
Pfizer
07/16/24
-
7
COMPOSITIONS AND METHODS OF TREATING CONDITIONS
The Uab Research Foundation
07/16/24
-
1
INDOLINE COMPOUND
Medshine Discovery
07/16/24
-
217
INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE
Cornell University
07/16/24
-
4
MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF
Goharmony Therapeutics (Shenzhen) Co.
07/16/24
-
35
NRF2-ACTIVATING COMPOUND
Senju Pharmaceutical Co.
07/16/24
-
2
PHENOL DERIVATIVE AND APPLICATION THEREOF IN MEDICAMENTS
Hinye Pharmaceutical Co.
07/16/24
-
3
PYRIDINE DERIVATIVES AS MODULATORS OF SORTILIN ACTIVITY
Insusense
07/16/24
-
1
SALT FORM AND CRYSTAL FORM OF PYRAZOLE SUBSTITUTED IMIDAZO[1,2- A]QUINOXALINE DERIVATIVE
Ocumension Therapeutics (Suzhou) Co.
07/16/24
-
5
SUBSTITUTED N-(2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-5-YL)ARYLSULFONAMIDE ANALOGS AS MODULATORS OF CEREBLON PROTEIN
St. Jude Children'S Research Hospital
07/16/24
-
40
SULFOXIMIDE SUBSTITUTED INDAZOLE IRAK4 KINASE INHIBITOR, PREPARATION METHOD THEREOF AND USE THEREOF
Shanghai Xunhe Pharmaceutical Technology Co.
07/16/24
-
6
TETRAHYDRO-1H-PYRIDO[3,4-b]INDOLE ANTI-ESTROGENIC DRUGS
Olema Pharmaceuticals
07/16/24
-
50
1,3,4,7-tetrahydro-2H-pyrrolo[3′,2′:5,6]pyrido[2,3-b][1,4]oxazepine bcl-2 inhibitors
Abbvie
07/13/24
-
49
Modulators of STING (stimulator of interferon genes)
Pfizer
07/13/24
-
315
Substituted bicyclic compounds useful as T cell activators
Bristol-Myers Squibb
07/13/24
-
178
Arylamide derivative having antitumor activity
Chugai Seiyaku Kabushiki Kaisha
07/12/24
-
8
Compounds for treating or inhibiting recurrence of acute myeloid leukemia
Flash Therapeutics
07/12/24
-
12
Inhibitors for coronavirus
Southwest Research Institute
07/12/24
-
382
Substituted aminothiazoles as DGKzeta inhibitors for immune activation
Bayer Aktiengesellschaft
07/12/24
-
115
Substituted phenyloxazolidinones for antimicrobial therapy
The Global Alliance For Tb Drug Development
07/12/24
-
17
ATF6 INHIBITORS AND USES THEREOF
Altos Labs
07/09/24
-
32
AZA-ERGOLINE DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Shanghaitech University
07/09/24
-
19
BRANCHED MACROCYCLIC 4-(PYRAZOL-5-YL)-INDOLE DERIVATIVES AS INHIBITORS OF MCL-1
Janssen Pharmaceutica
07/09/24
-
16
COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS
Case Western Reserve University
07/09/24
-
115
HYDROXYHETEROCYCLOALKANE-CARBAMOYL DERIVATIVES
Idorsia Pharmaceuticals
07/09/24
-
3
Methods for the Treatment of Fibrotic Disease
Shy Therapeutics
07/09/24
-
43
Novel SIK Inhibitors
Pfizer
07/09/24
-
28
PIM KINASE INHIBITOR
Hangzhou Biosun Pharmaceutical Co.
07/09/24
-
39
PYRIMIDINE CARBOXAMIDE COMPOUND AND USE THEREOF
Shanghai Meiyue Biotech Development Co.
07/09/24
-
119
Pyrido[2,3-D]Imidazole Derivatives and Their Use As Inhibitors of ITK for the Treatment of Skin Disease
Pfizer
07/09/24
-
54
SPIROCYCLIC-SUBSTITUTED 6,7-DIHYDRO-PYRANO[2,3-d]PYRIMIDINE INHIBITORS OF KRAS G12C MUTANT
Merck Sharp & Dohme
07/09/24
-
9
THERAPY BASED ON SYNTHETIC LETHALITY IN SWI/SNF COMPLEX-DYSFUNCTION CANCER
National Cancer Center
07/09/24
-
82
TRICYCLIC COMPOUND AND USE THEREOF
Nanjing Zaiming Pharmaceutical Co.
07/09/24
-
236
Benzodioxane modulators of leukotriene A4 hydrolase (LTA4H) for prevention and treatment of aging-associated diseases
Alkahest
07/03/24
-
27
Inhibitors of bacterial glutaminyl cyclases for use in the treatment of periodontal and related diseases
Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung
07/03/24
-
26
JAK1 pathway inhibitors for the treatment of vitiligo
Incyte
07/03/24
-
22
Leucine-rich repeat kinase 2 (LRRK2) inhibitors
H. Lundbeck
07/03/24
-
568
Modulators of HSD17B13 and methods of use thereof
Regeneron Pharmaceuticals
07/03/24
-
44
Pyrazole compounds, pharmaceutical compositions thereof and use thereof
Artivila (Shenzhen) Innovation Center
07/03/24
-
8
Urea compounds and compositions as SMARCA2/BRM ATPase inhibitors
Novartis
07/03/24
-
64
BENZOTHIAZOLE AND QUINOLINE DERIVATIVES AND THEIR USE
Shanghai Yao Yuan Biotechnology Co., Ltd.
06/29/24
-
74
COMPOUNDS AND METHODS FOR MODULATING FXR
Terns Pharmaceuticals, Inc.
06/29/24
-
8
Compounds for Disease Treatment
Duke University
06/29/24
-
53
HETEROAROMATIC COMPOUNDS
AstraZeneca AB
06/29/24
-
264
HETEROCYCLIC AMIDE AND UREA COMPOUNDS AS JAK2 INHIBITORS
Ajax Therapeutics, Inc.
06/29/24
-
288
Heterocycles as WIP1 Inhibitors
PMV Pharmaceuticals, Inc.
06/29/24
-
215
IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS IRAK4 INHIBITORS AND THEIR USE IN THE TREATMENT OF DISEASE
BIOGEN MA INC.
06/29/24
-
102
INHIBITION OF nSMase FOR THE TREATMENT OF HUMAN
IMMUNODEFICIENCY VIRUS INFECTION
The Johns Hopkins University
06/29/24
-
224
KIT KINASE INHIBITORS AND METHODS OF USE THEREOF
Deciphera Pharmaceuticals, LLC
06/29/24
-
3
METHODS OF TREATING CANCER USING HETEROARYL-BIPHENYL AMIDE DERIVATIVES
CHEMOCENTRYX, INC.
06/29/24
-
20
NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF
Jacobio Pharmaceuticals Co., Ltd.
06/29/24
-
10
NOVEL GLUTAMINYL CYCLASE INHIBITORS AND THE USE THEREOF IN TREATMENT OF VARIOUS DISEASES
LTD "VALENTA-INTELLEKT"
06/29/24
-
58
PYRIDO OXAZINE DERIVATIVES AS ALK5 INHIBITORS
CHIESI FARMACEUTICI S.P.A.
06/29/24
-
49
PYRIDO OXAZINE DERIVATIVES AS ALK5 INHIBITORS
CHIESI FARMACEUTICI S.P.A.
06/29/24
-
8
QUINOLINE MERCAPTOACETATE SULFONAMIDE DERIVATIVE, INTERMEDIATE, PHARMACEUTICAL DERIVATIVE OR FORMULATION, AND PREPARATION METHOD AND USE THEREFOR
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.
06/29/24
-
1044
SARS-COV2 MAIN PROTEASE INHIBITORS
Gilead Sciences, Inc.
06/29/24
-
25
SMALL MOLECULE REGULATORS OF ALVEOLAR TYPE 2 CELL PROLIFERATION FOR THE TREATMENT OF PULMONARY DISEASES
THE SCRIPPS RESEARCH INSTITUTE
06/29/24
-
3
SUBSTITUTED TRICYCLIC COMPOUND AS PRMT5 INHIBITOR AND USE THEREOF
NANJING SANHOME PHARMACEUTICAL CO., LTD.
06/29/24
-
7
TARGET FOR SCREENING ANTI-TUMOR DRUG, USE THEREOF AND SCREENING METHOD THEREFOR
SHENYANG FUYANG PHARMACEUTICAL TECHNOLOGY CO., LTD.
06/29/24
-
27
Quinolines and azaquinolines as inhibitors of CD38
Boehringer Ingelheim International GmbH
06/27/24
-
3
TRK inhibitors useful as anticancer drugs
TYLIGAND BIOSCIENCE (SHANGHAI) LIMITED
06/27/24
-
448
ALPHA PROTEIN KINASE 1 INHIBITORS AND METHODS OF USE
Shanghai Yao Yuan Biotechnology Co.
06/20/24
-
523
AZABICYCLIC SHP2 INHIBITORS
IRBM
06/20/24
-
10
BENZIMIDAZOLE COMPOUND AND APPLICATION THEREOF
Medshine Discovery
06/20/24
-
6
BRIDGED HETEROCYCLYL-SUBSTITUTED PYRIMIDINE COMPOUNDS, PREPARATION METHOD AND MEDICAL USE THEREOF
The National Institutes Of Pharmaceutical R&D Co.
06/20/24
-
30
COMBINATION OF A T CELL THERAPY AND A DGK INHIBITOR
Juno Therapeutics
06/20/24
-
363
INDAZOLE COMPOUNDS AS KINASE INHIBITORS
Tyra Biosciences
06/20/24
-
69
LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF
Insilico Medicine Ip
06/20/24
-
56
NEW SPIRO[3H-INDOLE-3,2'-PYRROLIDIN]-2(1H)-ONE COMPOUNDS AND DERIVATIVES AS MDM2-P53 INHIBITORS
Boehringer Ingelheim International
06/20/24
-
101
NOVEL ACC INHIBITORS
Pfizer
06/20/24
-
22
PREPARATION AND APPLICATION METHOD OF HETEROCYCLIC COMPOUNDS AS KRAS INHIBITOR
Shanghai Kechow Pharma
06/20/24
-
485
PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS
Actelion Pharmaceuticals
06/20/24
-
19
PYRIMIDINES FOR DEGRADING BRUTON'S TYROSINE KINASE
Abbvie
06/20/24
-
4
SERIES OF PIPERIDINE-SUBSTITUTED BENZOIC ACID COMPOUNDS, AND USE THEREOF
Medshine Discovery
06/20/24
-
84
SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVES, COMPOSITIONS AND PHARMACEUTICAL USES THEREOF
Shanghai Haiyan Pharmaceutical Technology Co.
06/20/24
-
245
TRIAZOLYL-METHYL SUBSTITUTED ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES
Idorsia Pharmaceuticals
06/20/24
-
135
TRICYCLIC PYRIMIDINES AS CYCLIN-DEPENDENT KINASE 7 (CDK7) INHIBITORS
Janssen Pharmaceutica
06/20/24
-
10
Dizocilpine derivatives as peripheral NMDA receptor antagonists
Institut National De La Sante Et De La Recherche Medicale (Inserm
06/17/24
-
65
IRE1 small molecule inhibitors
Cornell University
06/17/24
-
33
Imidazo[4,5-c]pyridine compounds as LSD-1 inhibitors
Regents Of The University Of Michigan
06/17/24
-
40
INHIBITORS OF METTL3
Strom Therapeutics
06/12/24
-
95
CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF
Shanghai Pharmaceuticals Holding Co.
06/11/24
-
217
COMPOUNDS FOR TREATING CERTAIN LEUKEMIAS
Terns Pharmaceuticals
06/11/24
-
1
CRYSTAL FORM AND SALT FORM OF BROMINE DOMAIN PROTEIN INHIBITOR AND PREPARATION METHOD THEREFOR
Chia Tai Tianqing Pharmaceutical Group Co.
06/11/24
-
506
DIHYDROOXADIAZINONE COMPOUND AND PHARMACEUTICAL USE THEREOF
Japan Tobacco
06/11/24
-
60
ERAP INHIBITORS
Universite De Lille
06/11/24
-
20
HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Shenzhen Chipscreen Biosciences Co.
06/11/24
-
133
INHIBITORS OF QPCTL AND QPCT
TBA
06/11/24
-
9
NOVEL TETRAZOLES
Boehringer Ingelheim International
06/11/24
-
10
PROTEIN-PROTEIN INTERACTION MODULATORS OF AURORA KINASE A AND THEIR USE IN THE PREVENTION AND/OR TREATMENT OF CANCER
Eberhard Karls Universitat Tubingen
06/11/24
-
419
PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
Xenon Pharmaceuticals
06/11/24
-
11
TRICYCLIC KINASE INHIBITORS AND USES THEREOF
Dana-Farber Cancer Institute
06/11/24
-
9
TRICYCLIC UBIQUITIN SPECIFIC PROTEASE 1 INHIBITOR AND USE THEREOF
Shandong Xuanzhu Pharma Co.
06/11/24
-
3
Methods and compositions relating to steroid hormone receptor-dependent proliferative disorders
Wayne State University
06/07/24
-
15
BRIDGED COMPOUNDS AS KRAS G12D INHIBITOR AND DEGRADER AND THE USE THEREOF
Beigene Switzerland
06/04/24
-
575
CONDENSED HETEROCYCLIC COMPOUND
Nissan Chemical
06/04/24
-
92
DIHYDRO-CYCLOPENTA-ISOQUINOLINE SULFONAMIDES DERIVATIVES
Ucb Biopharma
06/04/24
-
86
HETEROAROMATIC COMPOUNDS AND USES THEREOF
Hutchison Medipharma
06/04/24
-
131
Heterocycle RMB39 Modulators
Recursion Pharmaceuticals
06/04/24
-
175
Heterocyclic Carboxylate Compounds as Glycolate Oxidase Inhibitors
Lilac Therapeutics
06/04/24
-
392
IMIDAZOLO INDAZOLE COMPOUNDS AS JAK INHIBITORS
Theravance Biopharma R&D Ip
06/04/24
-
169
MNK INHIBITORS
Hepagene Therapeutics (Hk
06/04/24
-
77
MU-OPIOID RECEPTOR AGONISTS AND USES THEREFOR
Kures
06/04/24
-
29
NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR
Sanofi
06/04/24
-
40
Non-Covalent Inhibitors of the Main Protease of SARS-CoV-2 and Methods of Use
Yale University
06/04/24
-
5
PYRIDINE COMPOUNDS AS ALLOSTERIC SHP2 INHIBITORS
Revolution Medicines
06/04/24
-
122
QUINAZOLINE COMPOUNDS AND METHODS OF USE
Iambic Therapeutics
06/04/24
-
4
USE OF 5-[[4-[2-[5-ACETYLPYRIDIN-2-YL]ETHOXY]BENZYL]-1,3-THIAZOLIDINE-2,4-DIONE AND ITS SALTS
Minoryx Therapeutics
06/04/24
-
34
Anti-cancer/anti-fibrosis compounds
The Regents Of The University Of California
06/01/24
-
426
2-Methyl-Quinazolines
Bayer Pharma Aktiengesellschaft
05/30/24
-
13
ANTAGONISTS OF THE ADENOSINE A2A RECEPTOR
Adorx Therapeutics
05/30/24
-
14
BORATE DERIVATIVE AND USES THEREOF
Reistone Biopharma Company
05/30/24
-
37
COMPOSITIONS AND METHODS FOR INHIBITING M PRO PROTEASE ACTIVITY AND FOR PREVENTING AND TREATING SARS-COV-2 INFECTION
Arizona Board Of Regents On Behalf Of The University Of Arizona
05/30/24
-
126
CYCLIC AMINE DERIVATIVES HAVING SEROTONIN RECEPTOR BINDING ACTIVITY
Shionogi & Co.
05/30/24
-
208
GCN2 MODULATING COMPOUNDS AND USES THEREOF
Hibercell
05/30/24
-
31
MACROCYCLIC BRANCHED 3-FLUORO-BUT-3-ENAMIDES AS INHIBITORS OF MCL-1
Janssen Pharmaceutica
05/30/24
-
22
Nitrogen Containing 2,3-Dihydroquinazolinone Compounds as Nav1.8 Inhibitors
Glaxosmithkline Intellectual Property Development
05/30/24
-
24
OXALAMIDE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY
Ifm Due
05/30/24
-
228
PYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS BTK INHIBITORS
Biogen Ma
05/30/24
-
9
PYRIMIDINE CARBOXAMIDE COMPOUND AND APPLICATION THEREOF
Shanghai Meiyue Biotech Development Co.
05/30/24
-
19
Polycyclic Kinase Inhibitor
Shandong Xuanzhu Pharma Co.
05/30/24
-
55
SMALL MOLECULE INHIBITOR FOR CATHEPSIN C AND MEDICINAL USE THEREOF
Reistone Biopharma Company
05/30/24
-
135
TETRAHYDROTHIENOPYRIMIDINESULFONAMIDE COMPOUNDS
Modulus Discovery
05/30/24
-
161
1,2,4-triazole derivatives as tankyrase inhibitors
Oslo Universitetssykehus
05/23/24
-
46
Aminopyrazine diol compounds as PI3K-γ inhibitors
Incyte
05/23/24
-
155
Diacylglyercol kinase modulating compounds
Gilead Sciences
05/23/24
-
41
ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY
Merck Sharp & Dohme
05/22/24
-
26
Combination therapy comprising JAK pathway inhibitor and rock inhibitor
Incyte
05/17/24
-
55
Fused ring compound having urea structure
Sanford Burnham Prebys Medical Discovery Institute
05/17/24
-
256
Inhibitors of the menin-MLL interaction
Syndax Pharmaceuticals
05/17/24
-
106
P2X3 andor P2X2/3 receptor antagonist, pharmaceutical composition comprising same, and use thereof
Beijing Tide Pharmaceutical Co.
05/17/24
-
103
Substituted pyrrolidones and piperidones as small molecule inhibitors of EZH2 and EED protein binding
Northwestern University
05/17/24
-
107
Substituted tetrahydrofurans as modulators of sodium channels
Vertex Pharmaceuticals
05/17/24
-
14
Sulfonylamide compounds as CDK2 inhibitors
Incyte
05/17/24
-
34
[1,2,4]triazolo[1,5-a]pyridine compound as JAK inhibitor and use thereof
Zhuhai United Laboratories Co.
05/17/24
-
186
ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS
Avilar Therapeutics
05/10/24
-
67
HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF
Lg Chem
05/10/24
-
9
KETOHEXOKINASE INHIBITOR AND USE THEREOF
Sichuan Haisco Pharmaceutical Co.
05/10/24
-
36
MACROCYCLIC SPIROCYCLE DERIVATIVES AS MCL-1 INHIBITORS
Janssen Pharmaceutica
05/10/24
-
191
MODIFIED PROTEINS AND PROTEIN DEGRADERS
Cullgen (Shanghai)
05/10/24
-
44
NAPHTHYRIDINE AND PYRIDO[3,4-c]PYRIDAZINE DERIVATIVES AS GABAA ALPHA 5 RECEPTOR MODULATORS
Richter Gedeon
05/10/24
-
145
PYRAZOLE DERIVATIVES USEFUL AS NAMPT MODULATORS
Cytokinetics
05/10/24
-
43
SMALL-MOLECULE MODULATORS OF THE ORPHAN NUCLEAR RECEPTOR TLX
Baylor College Of Medicine
05/10/24
-
47
19-nor neuroactive steroids and methods of use thereof
Sage Therpeutics
05/03/24
-
400
6-azaindole compounds
Bristol-Myers Squibb
05/03/24
-
4
Compound, preparation method and use thereof
Guangxi Jiufu Biotechnology Co.
05/03/24
-
126
Compounds
CTXT PTY
05/03/24
-
639
Compounds for modulating S1P1 activity and methods of using the same
Trevena
05/03/24
-
2
Crystalline and salt forms of PPAR agonist compounds
Mitobridge
05/03/24
-
175
GCN2 and perk kinase inhibitors and methods of use thereof
Deciphera Pharmaceuticals
05/03/24
-
155
Isoindolinone compounds
Monte Rosa Therapeutics
05/03/24
-
331
LPA receptor antagonists and uses thereof
Gilead Sciences
05/03/24
-
10
LRRK2 inhibiting compounds and use thereof for treating neurodegenerative diseases
Consejo Superior De Investigaciones Cientificas
05/03/24
-
16
Multi-targeted tyrosine kinase inhibitors and their pharmaceutical uses
Shanghai AB Pharmatech
05/03/24
-
3
S6K1 protein kinase inhibitors as cancer therapeutics
Xavier University Of Louisiana
05/03/24
-
48
Spiropyrrolidine derived antiviral agents
Enanta Pharmaceuticals
05/03/24
-
30
COMPOUND CONTAINING 1,3-BENZODIOXOL STRUCTURE AND PREPARATION METHOD AND USE THEREOF
Xi'An Xintong Pharmaceutical Research
04/24/24
-
9
Cereblon Ligands and Uses Thereof
Regents Of The University Of Michigan
04/24/24
-
15
Cereblon Ligands and Uses Thereof
Regents Of The University Of Michigan
04/24/24
-
3
DENDRIMER COMPOSITIONS AND METHODS FOR DRUG DELIVERY TO THE EYE
Ashvattha Therapeutics
04/24/24
-
384
ENZYME INHIBITORS
Kalvista Pharmaceuticals
04/24/24
-
69
HETEROCYCLIC G-PROTEIN-COUPLED RECEPTOR 52 (GPR52) AGONISTS
Board Of Regents, The University Of Texas System
04/24/24
-
513
HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE
Amgen
04/24/24
-
103
NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS
Merck Sharp & Dohme
04/24/24
-
6
NOVEL GALACTOSIDE INHIBITOR OF GALECTINS
Galecto Biotech
04/24/24
-
36
PIPERIDINYLPYRIDINYLCARBONITRILE DERIVATIVES AS INHIBITORS OF GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE AND GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE PROTEIN
Boehringer Ingelheim International
04/24/24
-
13
Pyridine and Pyrazine derivative for the Treatment of CF, COPD, and Bronchiectasis
Novartis
04/24/24
-
80
Substituted phenyl ethynyl pyridine carboxamides as potent inhibitors of SARS virus
Southern Research Institute
04/24/24
-
26
THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS
Terns Pharmaceuticals
04/24/24
-
38
THYROID HORMONE RECEPTOR b SELECTIVE AGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF
Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences
04/24/24
-
26
TREATMENT OF URTICARIA USING JAK INHIBITORS
Incyte
04/24/24
-
36
2-aminoaryl-5-aryloxazole analogs for the treatment of neurodegenerative diseases
Southern Research Institute
04/23/24
-
4
3-CYCLIC AMINE-INDOLE DERIVATIVES AS SEROTONERGIC AGENTS FOR THE TREATMENT OF CNS DISORDERS
Mindset Pharma
04/23/24
-
2
4-AMINO-3-(4-PHENOXYPHENYL)-1,3-DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE DERIVATIVES AND SALTS THEREOF
Genzyme
04/23/24
-
13
Anti-malarial agents
The Board Of Regents Of The University Of Texas System
04/23/24
-
2
BENZOPYRAZOLE INHIBITORS OF SARM1
Disarm Therapeutics
04/23/24
-
4
CARBORANE HYDROXAMIC ACID MATRIX METALLOPROTEINASE INHIBITORS AND AGENTS FOR BORON NEUTRON CAPTURE THERAPY
Loyola University Of Chicago
04/23/24
-
120
Chemical modulators of store-operated calcium channels and their therapeutic applications
The Texas A&M University System
04/23/24
-
30
DIACYLGLYCEROL KINASE (DGK) ALPHA INHIBITORS AND USES THEREOF
Insilico Medicine Ip
04/23/24
-
126
HMOX1 INDUCERS
Mitobridge
04/23/24
-
66
ISOINDOLINONE COMPOUNDS
Monte Rosa Therapeutics
04/23/24
-
5
Inhibitors for the B-catenin/B-cell lymphoma 9 (BCL9) protein-protein interaction
H. Lee Moffitt Cancer Center and Research Institute
04/23/24
-
4
Inhibitors of SARM1 NADase activity and uses thereof
Washington University
04/23/24
-
61
METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE
Design Therapeutics
04/23/24
-
32
PEPTIDE MACROCYCLES AGAINST ACINETOBACTER BAUMANNII
Hoffmann-La Roche
04/23/24
-
51
PYRROLO[3,2-B]PYRIDINE DERIVATIVES USEFUL IN TREATING CONDITIONS ASSOCIATED WITH CGAS
Novartis
04/23/24
-
11
Phenoxyacetic acid derivatives, preparation method thereof and use thereof as medicament
China Pharmaceutical University
04/23/24
-
72
Receptor inhibitors, pharmaceutical compositions comprising the same and use thereof
Beijing Tide Pharmaceutical
04/23/24
-
87
SOS1 INHIBITORS AND USES THEREOF
Qilu Regor Therapeutics
04/23/24
-
6
TREATMENTS FOR OBSESSIVE COMPULSIVE DISORDER
Sirgartan Holdings
04/23/24
-
12
2-phenyl-3,4-dihydropyrrolo[2,1 -f] [1,2,4]triazinone derivatives as phosphodiesterase inhibitors and uses thereof
Topadur Pharma
04/18/24
-
20
Isoxazolidines as RIPK1 inhibitors and use thereof
Genzyme
04/18/24
-
35
Pyridine macrocycle compounds as ASK1 inhibiting agents
Biogen Ma
04/18/24
-
83
Tricyclic heterocycles as FGFR inhibitors
Incyte
04/18/24
-
130
6-phenyl-4,5-dihydropyridazin-3(2H)-one derivatives as PDE3A and PDE3B inhibitors for treating cancer
Bayer Aktiengesellschaft
04/17/24
-
98
ErbB/BTK inhibitors
Dizal (Jiangsu) Pharmaceutical
04/17/24
-
183
Heterocyclic GLP-1 agonists
Gasherbrum Bio
04/17/24
-
2
Indazole amine derivative, preparation method therefor and medical use thereof
Zhejiang Hisun Pharmaceutical
04/17/24
-
3
1,3-DIHYDRO-2H-PYRROLO[3,4-C]PYRIDINE DERIVATIVES AS GABAA A5 RECEPTOR MODULATORS
Richter Gedeon
04/12/24
-
16
ANTI-HER2 IMMUNOCONJUGATES, AND USES THEREOF
Bolt Biotherapeutics
04/12/24
-
372
APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
Abbvie
04/12/24
-
658
CD73 COMPOUNDS
Gilead Sciences
04/12/24
-
125
COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY
Case Western Reserve University
04/12/24
-
70
COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING
Neuropore Therapies
04/12/24
-
159
COMPOUNDS AS C5AR INHIBITORS
Kira Pharmaceuticals (Suzhou)
04/12/24
-
25
COMPOUNDS FOR THE TREATMENT OF SARS
Purdue Research Foundation
04/12/24
-
120
HETEROARYL CARBOXAMIDE COMPOUND
Astellas Pharma
04/12/24
-
160
MACROCYCLIC COMPOUNDS AS PROTEASOME INHIBITORS
Cornell University
04/12/24
-
22
NOVEL BIPHENYL DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF
Xi'An Xinton Pharmaceutcal Research
04/12/24
-
21
POTENT AND SELECTIVE IRREVERSIBLE INHIBITORS OF IRAK1
Dana-Farber Cancer Institute
04/12/24
-
50
SELECTIVE ESTROGEN RECEPTOR DEGRADERS AND USES THEREOF
Inventisbio
04/12/24
-
93
Small Molecule Inhibitors of KRAS G12C Mutant
Merck Sharp & Dohme
04/12/24
-
29
TRIAZOLONE COMPOUNDS AND USES THEREOF
Tempest Therapeutics
04/12/24
-
18
HDAC6 inhibitors and imaging agents
The General Hospital
04/08/24
-
23
Indole compounds and their use
Ariagen
04/08/24
-
108
Monoacylglycerol lipase modulators
Janssen Pharmaceutica
04/08/24
-
76
Pyrazolopyridine compounds and uses thereof
Incyte
04/08/24
-
18
Quinolines that modulate SERCA and their use for treating disease
Neurodon
04/08/24
-
10
Small molecule modulators of pantothenate kinases
St. Jude Children'S Research Hospital
04/08/24
-
3
Sulfonamide or sulfinamide compound having effect of inducing BRD4 protein degradation and pharmaceutical use thereof
Mitsubishi Tanabe Pharma
04/08/24
-
24
Tetrazole derivatives as TRPA1 inhibitors
Boehringer Ingelheim International
04/08/24
-
60
ANTI-PD-L1 IMMUNOCONJUGATES, AND USES THEREOF
Bolt Biotherapeutics
04/04/24
-
99
AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE
Iambic Therapeutics
04/04/24
-
4
CDK INHIBITORS
Qilu Regor Therapeutics
04/04/24
-
194
HETEROCYCLIC COMPOUND, INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Wuhan Ll Science and Technology Development
04/04/24
-
293
HSD17B13 INHIBITORS AND USES THEREOF
Fl2022-001
04/04/24
-
103
Heterocyclic Derivatives as P2X7 Receptor Antagonists
Breye Therapeutics
04/04/24
-
35
IMIDAZOLE COMPOUNDS AS INHIBITORS OF ENPP1
Stingray Therapeutics
04/04/24
-
8
INHIBITORS OF POSITIVE STRAND RNA VIRUSES
National Health Research Institutes
04/04/24
-
82
NOVEL POTASSIUM CHANNEL INHIBITORS
Saniona
04/04/24
-
47
PYRAZOLO DERIVATIVES AS HUMAN DIHYDROOROTATE DEHYDROGENASE (HDHODH) INHIBITORS FOR USE AS ANTIVIRALS
Drug Discovery and Clinic
04/04/24
-
137
TRICYCLIC COMPOUNDS AS EGFR INHIBITORS
Qilu Pharmaceutical
04/04/24
-
45
IRAK degraders and uses thereof
Kymera Therapeutics
04/03/24
-
86
Compounds and their uses as MIF inhibitors
Nanjing Immunophage Biotech Co.
03/25/24
-
51
Purinone compounds and their use in treating cancer
Astrazeneca
03/21/24
-
2
Substituted oxopyridine derivative
Bayer Pharma Aktiengesellschaft
03/21/24
-
258
AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF
Genentech
03/19/24
-
29
COMPOUND USED AS KINASE INHIBITOR AND USE THEREOF
Tyk Medicines
03/19/24
-
503
COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
Dong-A St Co.
03/19/24
-
3
Compositions and Methods for Managing Weight
Unigen
03/19/24
-
289
PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES
Hoffmann-La Roche
03/19/24
-
248
PYRIMIDINE-AND NITROGEN-CONTAINING BICYCLIC COMPOUND
Asahi Kasei Pharma
03/19/24
-
108
RIPK1 INHIBITORS AND METHODS OF USE
Merck Sharp & Dohme
03/19/24
-
66
SALT INDUCIBLE KINASE INHIBITORS
The General Hospital
03/19/24
-
9
TETRACYCLIC COMPOUNDS AS DGK INHIBITORS
Incyte
03/19/24
-
187
TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS
Merck Patent
03/19/24
-
11
TRIHETEROCYCLIC DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF
Shanghai De Novo Pharmatech Co.
03/19/24
-
148
Bicyclic compounds and their uses
Novartis
03/14/24
-
320
Inhibitors of peptidylarginine deiminases
Gilead Sciences
03/14/24
-
35
BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF
2692372 Ontario
03/13/24
-
5
BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE
Prelude Therapeutics
03/13/24
-
26
COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL DISORDERS
Kineta
03/13/24
-
46
COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF
Medifron Dbt
03/13/24
-
210
CYCLIC COMPOUNDS AND METHODS OF USING SAME
SchröDinger
03/13/24
-
83
MODIFIED IMIDAZOPYRIDINES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
Merck Sharp & Dohme
03/13/24
-
24
MODULATORS OF FPR1 AND METHODS OF USING THE SAME
Biofront
03/13/24
-
18
NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME
Tme Therapeutics
03/13/24
-
188
PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS
Chiesi Farmaceutici
03/13/24
-
24
PYRIDO[4,3-b]INDOLE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS
Ventus Therapeutics U.S.
03/13/24
-
1
SALT OF COMPOUND FOR DEGRADING BTK, CRYSTAL FORM THEREOF, AND USE THEREOF IN MEDICINE
Haisco Pharmaceuticals
03/13/24
-
4
BROMODOMAIN INHIBITORS FOR ANDROGEN RECEPTOR-DRIVEN CANCERS
Forma Therapeutics
03/12/24
-
11
COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS
Beth Israel Deaconess Medical Center
03/12/24
-
34
Fused pyrimidine derivatives as A2A/A2B inhibitors
Incyte
03/07/24
-
49
Indanes as PD-L1 inhibitors
Chemocentryx
03/07/24
-
178
Pyridazinone compounds and uses thereof
Edgewise Therapeutics
03/07/24
-
42
Trans-indoline cyclopropylamine chemical compound, and method for preparation, pharmaceutical composition, and use thereof
Shanghai Institute of Materia Medica
03/07/24
-
20
ABHD6 ANTAGONIST
Ono Pharmaceutical Co.
03/04/24
-
89
MASP INHIBITORY COMPOUNDS AND USES THEREOF
Bayer Aktiengesellschaft
03/04/24
-
18
MODULATORS OF PROGRAMMED DEATH-LIGAND-1
Southern Research Institute
03/04/24
-
32
PYRIMIDINYL SULFONAMIDES AS INHIBITORS OF ACK1/TNK2 TYROSINE KINASE
H. Lee Moffitt Cancer Center and Research Institute
03/04/24
-
51
TETRAZOLE DERIVATIVES
Merck Patent
03/04/24
-
16
TRIAZINE DIONE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE
Jiangsu Hengrui Pharmaceuticals Co.
03/04/24
-
181
Benzo[c][2,6]naphthyridine derivatives, compositions and therapeutic uses thereof
Cambridge Enterprise
03/02/24
-
83
Heteroaryl-biphenyl amines for the treatment of PD-L1 diseases
Chemocentryx
03/02/24
-
210
Modulators of Cystic Fibrosis Transmembrane Conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulators
Vertex Pharmaceuticals
03/02/24
-
288
Naphthyridinone compounds useful as T cell activators
Bristol-Myers Squibb
03/02/24
-
136
Streptococcus mutans glucosyl transferase inhibitors for dental caries therapy
Uab Research Foundation
03/02/24
-
107
Substituted indazoles as IRAK4 inhibitors
Astrazeneca
03/02/24
-
421
4-ALKOXYPYRROLO[2,1-F][1,2,4]TRIAZINES AND PREPARATION AND USES THEREOF
Biosplice Therapeutics
02/28/24
-
11
ANTICHOLINERGIC AGENTS
Rezubio Pharmaceuticals Co.
02/28/24
-
126
COMBINATION OF AN ALPHA2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONIST WITH A TASK1/3 CHANNEL BLOCKER FOR THE TREATMENT OF SLEEP APNEA
Bayer Aktiengesellschaft
02/28/24
-
12
COMPOUNDS AND USE THEREOF IN METHODS OF TREATMENT
University of Queensland
02/28/24
-
1
DEUTERIUM-MODIFIED THIENOPYRIDONE COMPOUND
Chia Tai Tianqing Pharmaceutical Group Co.
02/28/24
-
1
METHOD FOR PREPARING BTK DEGRADING AGENT
Haisco Pharmaceuticals
02/28/24
-
3
PYRIDAZINE AND 1,2,4-TRIAZINE DERIVATIVES AS FGFR KINASE INHIBITORS
Beta Pharma
02/28/24
-
78
PYRIMIDINONE COMPOUNDS AND USES THEREOF
Hutchison Medipharma
02/28/24
-
5
PYRROLOPYRIDINE COMPOUND AND APPLICATION THEREOF
Medshine Discovery
02/28/24
-
26
REV-ERB AGONISTS
Saint Louis University
02/28/24
-
1
SALT OF PYRROLOPYRIMIDINE COMPOUND, CRYSTALLINE FORM THEREOF, AND APPLICATION THEREOF
Guangzhou Joyo Pharmatech Co.
02/28/24
-
44
SUBSTITUTED BENZO[f][l ,2,4JTRIAZOL0[4,3-a][l ,4JDIAZEPINES AS GABA A GAMMA! POSITIVE ALLOSTERIC MODULATORS
Hoffmann-La Roche
02/28/24
-
93
THERAPEUTIC COMPOUNDS AND METHODS
University of Minnesota
02/28/24
-
5
4-[[(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)amino]methyl]piperidin-3-ol compounds as CDK inhibitors
Carrick Therapeutics
02/22/24
-
21
Alkyne-containing antiviral agents
Enanta Pharmaceuticals
02/22/24
-
48
Cathepsin L inhibitors
Biofront Therapeutics (Beijing) Co.
02/22/24
-
46
Glycyrrhetinic acid derivatives for use in treating hyperkalemia
Ardelyx
02/22/24
-
144
Inhibiting agents for bruton's tyrosine kinase
Biogen Ma
02/22/24
-
15
Peptidomimetics for the treatment of Norovirus infection
Emory University
02/22/24
-
11
Pharmaceutical compositions comprising substituted nucleotides and nucleosides for treating viral infections
Emory University
02/22/24
-
24
ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE
Biointervene
02/19/24
-
37
AMIDE COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF
Artivila (Shenzhen) Innovation Center
02/19/24
-
3
BENZODIAZEPINE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF
China Pharmaceutical University
02/19/24
-
35
DIHYDROISOQUINOLINONE AND ISOINDOLINONE DERIVATIVES AND USES THEREOF
Hefei Institutes of Physical Science, Chinese Academy of Sciences
02/19/24
-
51
HETEROARYLQUINAZOLINE COMPOUNDS AS PROTEIN KINASE INHIBITORS
Chengdu Cynogen Bio-Pharmaceutical Technology
02/19/24
-
88
PYRIMIDINONE-CONTAINING 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS
Enanta Pharmaceuticals
02/19/24
-
8
INHIBITION OF THE HIV-1 REPLICATION BY COMPOUNDS DIRECTED AGAINST A NEW TARGET OF THE VIRAL CYCLE
Centre National De La Recherche Scientifique
02/18/24
-
7
PSMA INHIBITOR, COMPOUND AND APPLICATION
Peking University First Hospital
02/18/24
-
14
SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF IN NEURODEGENERATIVE DISEASES
Artivila Biopharma
02/18/24
-
3
USE OF PRIDOPIDINE AND ANALOGS FOR TREATING RETT SYNDROME
Prilenia Neurotherapeutics
02/18/24
-
137
Bicyclic amines as CDK2 inhibitors
Incyte
02/15/24
-
13
Fused bicyclic pyrimidine derivatives and uses thereof
The Regents of The University of Colorado, A Body Corporate
02/15/24
-
114
Substituted pyrazolo[1,5-A]pyrazine compounds as ret kinase inhibitors
Array Biopharma
02/15/24
-
118
Arginase inhibitors
Rijksuniversiteit Groningen
02/12/24
-
22
COMBINATIONS OF DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITORS AND ACETYL-COA CARBOXYLASE INHIBITOR
Pfizer
02/12/24
-
48
N-(2-(3-CYANO-2-AZABICYCLO[3.1.0]HEXAN-2-YL)-2-OXOETHYL)QUINOLINE-4-CARBOXAMIDES
Astrazeneca
02/12/24
-
2
SUBSTITUTED PYRROLO [2, 3-b] PYRIDINE AND PYRAZOLO [3, 4-b] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
Fochon Biosciences
02/12/24
-
118
1,3-substituted cyclobutyl derivatives and uses thereof
Novartis
02/08/24
-
818
Diacylglycerol kinase modulating compounds
Gilead Sciences
02/08/24
-
10
Glutaminyl cyclase inhibitors and the use thereof in treatment of various diseases
Ltd “Valenta-Intellekt”
02/08/24
-
8
Opioid compounds and uses thereof
Rhodes Technologies
02/08/24
-
1
Oral compositions of MK2 pathway inhibitor for treatment of immune conditions
Aclaris Therapeutics
02/08/24
-
140
USP30 inhibitors and uses thereof
Vincere Biosciences
02/08/24
-
7
ANTIBODIES FOR OPIOID TREATMENTS
The Scripps Research Institute
02/03/24
-
413
Acylsulfamide Compound and Pharmaceutical Use Therefor
Japan Tobacco
02/03/24
-
20
CD73 INHIBITOR AND USE THEREOF
Wuhan Humanwell Innovative Drug Research and Development Center
02/03/24
-
99
HIGH ACTIVITY HPK1 KINASE INHIBITOR
Adlai Nortye Biopharma Co.
02/03/24
-
27
IMIDAZO[1,2-a]PYRAZINE OR PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVE AND USE THEREOF
TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
02/03/24
-
7
RNA VIRUS INHIBITOR COMPOUNDS WITH IMPROVED METABOLIC STABILITY AND USES THEREOF
The Governors of The University of Alberta
02/03/24
-
136
TRICYCLIC TRIAZOLO COMPOUNDS AS DGK INHIBITORS
Incyte
02/03/24
-
25
Alkynyl(hetero)aromatic compound for inhibiting protein kinase activity
Shenzhen Targetrx
02/02/24
-
15
CDK8/19 inhibitors
Joint Stock Company “Biocad”
02/02/24
-
4
IRE1α inhibitors and uses thereof
The Regents of The University of California
02/02/24
-
4
Imidazopyridazine compounds and uses thereof
Incyte
02/02/24
-
6
Pyridinone-based epigenetic modifiers and uses thereof
The Board of Trustees of The University of Illinois
02/02/24
-
1
Radiolabelled MGL pet ligands
Janssen Pharmaceutica
02/02/24
-
62
Substituted nicotinimide inhibitors of BTK for treating cancer
Guangzhou Innocare Pharma Tech Co.
02/02/24
-
456
Pyrimidine derivatives as PGE2 receptor modulators
Idorsia Pharmaceuticals
02/01/24
-
25
3-TETRAZOLYLMETHYL-1,3,5-TRIAZIN-2,4-DIONE COMPOUND INHIBITING CORONAVIRUS 3CL PROTEASE ACTIVITY AND PREPARATION METHOD AND USE THEREOF
Shaanxi Panlong Pharmaceutical Co.
01/28/24
-
120
BICYCLIC INHIBITORS OF IRAK
Rigel Pharmaceuticals
01/28/24
-
12
BIPHENYL PYRROLIDINE AND BIPHENYL DIHYDROIMIDAZOLE DERIVATIVES FOR INHIBITING ACTIVITY OF 5-HT7 SEROTONIN RECEPTOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT
Korea Institute of Science and Technology
01/28/24
-
27
IMIDAZOPYRIDINE DERIVATIVES AND AZA-IMIDAZOPYRIDINE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF
Dana-Farber Cancer Institute
01/28/24
-
331
INHALED FORMULATIONS OF PGDH INHIBITORS AND METHODS OF USE THEREOF
Epirium Bio
01/28/24
-
123
INHIBITORS OF THE INTERACTION BETWEEN TRIP8B AND HCN CHANNELS AND USES THEREOF FOR TREATING NEUROLOGICAL DISEASES AND DISORDERS
Northwestern University
01/28/24
-
65
MALT1 MODULATORS AND USES THEREOF
Rheos Medicines
01/28/24
-
49
METTL3 INHIBITORY COMPOUNDS
Storm Therapeutics
01/28/24
-
39
MODIFIED BENZOFURAN-CARBOXAMIDES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
Merck Sharp & Dohme
01/28/24
-
12
MODULATORS OF PD-L1/PD-1 INTERACTION AND USES THEREOF
Ramot at Tel-Aviv University
01/28/24
-
22
SUBSTITUTED DIARYLAMINE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF
Suzhou Yabao Pharmaceutical R&D Co.
01/28/24
-
17
SUBSTITUTED S-ALANINATE DERIVATIVES
Bayer Aktiengesellschaft
01/28/24
-
3
USE OF PRIDOPIDINE AND ANALOGS FOR THE TREATMENT OF ANXIETY AND DEPRESSION
Prilenia Neurotherapeutics
01/28/24
-
322
cGAS INHIBITORS
Eli Lilly
01/28/24
-
304
Substituted indazoles as hematopoietic progenitor kinase 1 (HPK1) inhibitors
1St Biotherapeutics
01/24/24
-
15
1-methyl-4-[(4-phenylphenyl)sulfonylmethyl]cyclohexyanol and 1-methyl-4-[[4-(2-pyridyl)phenyl]sulfonylmethyl]cyclohexanol compounds and their therapeutic use
Modern Biosciences
01/23/24
-
16
Anti-cancer nuclear hormone receptor-targeting compounds
Nuvation Bio
01/23/24
-
101
Beta-lactam derivatives for the treatment of diseases
Insilico Medicine Ip
01/23/24
-
119
Compounds useful as inhibitors of isoprenylcysteine carboxyl methyltransferase
Agency For Science, Technology and Research
01/23/24
-
23
Heterocyclic compounds as pad inhibitors
Jubilant Epipad
01/23/24
-
1
SSTR4 agonist salts
Eli Lilly
01/23/24
-
23
Substituted amino six-membered nitric heterocyclic ring compound and preparation and use thereof
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
01/23/24
-
483
Substituted pyrimido[5,4-d]pyrimidines as HER2 inhibitors
Array Biopharma
01/23/24
-
152
COMPOUNDS FOR INHIBITING KIF18A
Volastra Therapeutics
01/19/24
-
2
CSF1R KINASE INHIBITOR AND USE THEREOF
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
01/19/24
-
55
FUSED TETRACYCLIC QUINAZOLINE DERIVATIVES AS INHIBITORS OF ERBB2
Enliven Therapeutics
01/19/24
-
30
GCN2 AND PERK KINASE INHIBITORS AND METHODS OF USE THEREOF
Deciphera Pharmaceuticals
01/19/24
-
316
HDAC6 INHIBITORS FOR TREATMENT OF METABOLIC DISEASE AND HFPEF
Tenaya Therapeutics
01/19/24
-
6
HETEROARYL HETEROCYCLIC COMPOUNDS AND USES THEREOF
Hutchison Medipharma
01/19/24
-
45
MEK INHIBITORS AND USES THEREOF
Ikena Oncology
01/19/24
-
31
N-AROMATIC AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF
Shenzhen Edk Pharmaceutical Technology
01/19/24
-
4
OXA- IBOGAINE INSPIRED ANALOGUES FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS
The Trustees of Columbia University In The City of New York
01/19/24
-
78
PYRAZOLEAMIDE DERIVATIVES
Hoffmann-La Roche
01/19/24
-
7
Phenyl-3,4-dihydroisoquinolin-2(1h)-yl-ethan-1-one derivatives as dopamine d1receptor positive allosteric modulators
Eli Lilly
01/19/24
-
390
SUBSTITUTED 4-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)THIOPHENE-2-CARBOXAMIDE DERIVATIVES AND USE THEREOF
The Johns Hopkins University
01/19/24
-
16
Anti-cancer nuclear hormone receptor-targeting compounds
Nuvation Bio
01/17/24
-
6
Conduritol aziridine derivatives and uses thereof
University of Saskatchewan
01/17/24
-
43
Pyrazine derivative and application thereof in inhibiting SHP2
Suzhou Genhouse Pharmaceutical
01/17/24
-
39
MACROCYCLIC PEPTIDE BORONATE IMMUNOMODULATORS
Bristol-Myers Squibb
01/16/24
-
212
5-SUBSTITUTED INDOLE 3-AMIDE DERIVATIVES, PREPARATION METHOD AND USE THEREOF
Origiant Pharmaceutical
01/12/24
-
13
BIPHENYL COMPOUND AS IMMUNOMODULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Shenzhen Chipscreen Biosciences
01/12/24
-
49
FUSED TRICYCLIC PYRIMIDINE-THIENO-PYRIDINE SMALL MOLECULE INHIBITORS OF UBIQUITIN-SPECIFIC PROTEASE 28
Dana-Farber Cancer Institute
01/12/24
-
84
HETEROCYCLIC PERICONDENSED CDC7 KINASE INHIBITORS FOR THE TREATMENT OF CANCER
SchrÖDinger
01/12/24
-
64
INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF
Haisco Pharmaceuticals
01/12/24
-
23
N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE
Pliant Therapeutics
01/12/24
-
135
PLK1 POLO BOX DOMAIN INHIBITORS AND METHOD OF TREATING CANCER
The United States of America,As Represented By The Secretary,Department of Health and Human Services
01/12/24
-
38
SUBSTITUTED PYRROLO-PYRIDINONE DERIVATIVES AND THERAPEUTIC USES THEREOF
The Broad Institute
01/12/24
-
20
TETRAHYDROISOQUINOLINE DERIVATIVE AND USE THEREOF
Medshine Discovery
01/12/24
-
79
BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF
The Florida International University Board of Trustees
01/11/24
-
154
COMPOUND AS BRAIN-PERMEABLE BTK OR HER2 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF
Chengdu Hyperway Pharmaceuticals
01/11/24
-
271
POLO LIKE KINASE 4 INHIBITORS
Oric Pharmaceuticals
01/11/24
-
88
QUINAZOLINE-2,4-DIAMINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT
The Asean Foundation
01/11/24
-
47
TRUXILLIC ACID MONOESTER-DERIVATIVES AS SELECTIVE FABP5 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
The Research Foundation For The State University of New York
01/11/24
-
22
Fused pyrrolines which act as ubiquitin-specific protease 30 (USP30) inhibitors
Forma Therapeutics
01/08/24
-
784
Inhibitors of glycogen synthase 1 (GYS1) and methods of use thereof
Maze Therapeutics
01/08/24
-
92
Inhibtors of Raf kinases
Kinnate Biopharma
01/08/24
-
54
Macrocyclic compounds for the treatment of medical disorders
Achillion Pharmaceuticals
01/08/24
-
8
Substituted pyrrolo[2,3-d]pyrimidines and pyrazolo[3,4-d]pyrimidines as inhibitors for multi-resistant cancers
Ferris State University
01/08/24
-
6
1H-PYRROLO[2,3-C]PYRIDINE COMPOUNDS AND APPLICATION THEREOF
Medshine Discovery
01/04/24
-
192
AGONISTS OF STIMULATOR OF INTERFERON GENES STING
The Scripps Research Institute
01/04/24
-
64
MACROCYCLIC COMPOUND
Asahi Kasei Pharma
01/04/24
-
169
NEW MACROCYCLIC LRRK2 KINASE INHIBITORS
Les Laboratoires Servier
01/04/24
-
10
PREPARATION OF BIARYL RING-LINKED AROMATIC HETEROCYCLIC DERIVATIVE AS IMMUNOMODULATOR AND USE THEREOF
Shanghai Longwood Biopharmaceuticals
01/04/24
-
69
PYRIDO[2,3-D]PYRIMIDIN-4-AMINES AS SOS1 INHIBITORS
Bayer Aktiengesellschaft
01/04/24
-
11
PYRROLOPYRIMIDINE COMPOUND AS BTK INHIBITOR AND USE THEREOF
Medshine Discovery
01/04/24
-
42
SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS
Artizan Biosciences
01/04/24
-
334
4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin specific protease 19 (USP19)
Almac Discovery
12/29/23
-
57
Fused tetracyclic quinazoline derivatives as inhibitors of ErbB2
Enliven Therapeutics
12/29/23
-
12
Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof
Haisco Pharmaceuticals
12/29/23
-
31
Prevention and/or treatment of CNS disorders
Ildong Pharmaceutical
12/29/23
-
1
Site specific homogeneous with KSP inhibitors
Bayer Pharma Aktiengesellschaft
12/29/23
-
13
Substituted pyrimidinones as agonists of the APJ receptor
Amgen
12/29/23
-
44
Sulfonamide derivatives for protein degradation
Dana-Farber Cancer Institute
12/29/23
-
100
INHIBITORS OF TYROSINE KINASE 2 MEDIATED SIGNALING
Abbvie
12/25/23
-
127
NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLOEOTIDE PYROPHOSPHATASE/PHOSPHODIESTE RASE INHIBITORY ACTIVITY, AND USE THEREOF
Txinno Bioscience
12/25/23
-
8
Toll-like receptor ligands
Inimmune
12/24/23
-
46
2-AMINOPYRIMIDINE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF
Guangzhou Salustier Biosciences
12/20/23
-
53
5-HT2A RECEPTOR INHIBITOR OR INVERSE AGONIST, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
Geneora Pharma (Shijiazhuang) Co.
12/20/23
-
37
A COMPOUND HAVING INHIBITORY ACTIVITY AGAINST KRAS G12D MUTATION
Taiho Pharmaceutical
12/20/23
-
16
BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF
Pharmaxis
12/20/23
-
33
BISPECIFIC ANTAGONISTS OF RETINOL-BINDING PROTEIN 4 THAT STABILIZE TRANSTHYRETIN TETRAMERS, THEIR PREPARATION, AND USE IN THE TREATMENT OF COMMON AGE-RELATED COMORBIDITIES
The Trustees of Columbia University In The City of New York
12/20/23
-
32
Benzimidazole derivatives
Hoffmann-La Roche
12/20/23
-
319
CARBOXYLIC ACID-CONTAINING COMPOUNDS AS MODULATORS OF BIS-PHOSPHOGLYCERATE MUTASE FOR THE TREATMENT OF SICKLE CELL DISEASE
Genzyme
12/20/23
-
176
GALECTIN-3 INHIBITING 2-HYDROXYCYCLOALKANE-1-CARBAMOYL DERIVATIVES
Idorsia Pharmaceuticals
12/20/23
-
29
HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF
Iomx Therapeutics
12/20/23
-
262
HETEROCYCLIC COMPOUNDS AND METHODS OF USE
SchröDinger
12/20/23
-
23
Heteroaryl Derivative, Preparation Method Therefor, And Use Thereof
Zhejiang Hisun Pharmaceutical
12/20/23
-
27
IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND THEIR USE AS ATM KINASE INHIBITORS
Deutsches Krebsforschungszentrum
12/20/23
-
623
OXOPYRROLIDINE FPR2 AGONISTS
Bristol-Myers Squibb
12/20/23
-
3
PYRROLIDINE COMPOUND AND USE THEREOF
Simcere Pharmaceutical
12/20/23
-
163
QUINAZOLINONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME
Repare Therapeutics
12/20/23
-
30
SUBSTITUTED PYRIDINES AS PARP1 INHIBITORS
Xinthera
12/20/23
-
7
SULFONYLUREA DERIVATIVE AND MEDICAL USES THEREOF
Shanghai Senhui Medicine
12/20/23
-
24
2-amino-N-(arylsulfinyl)-acetamide compounds as inhibitors of bacterial aminoacyl-tRNA synthetase
Oxford Drug Design
12/13/23
-
105
2-oxoimidazolidine-4-carboxamides as NAv1.8 inhibitors
Merck Sharp & Dohme
12/13/23
-
64
Azetidine and pyrrolidine PARP1 inhibitors and uses thereof
Xinthera
12/13/23
-
21
Compounds for the modulation of cyclophilins function
The University Court of The University of Edinburgh
12/13/23
-
481
Cyclobutyl amide monoacylglycerol lipase modulators
Janssen Pharmaceutica
12/13/23
-
76
Glutarimides for medical treatment
C4 Therapeutics
12/13/23
-
188
Heterocyclic compounds as monoacylglycerol lipase inhibitors
Hoffmann-La Roche
12/13/23
-
131
AMINO ALCOHOL COMPOUNDS AND USES THEREOF
Kineta
12/10/23
-
264
BIOMARKERS FOR CANCER THERAPY USING MDM2 ANTAGONISTS
Otsuka Pharmaceutical
12/10/23
-
153
CASEIN KINASE 1 DELTA MODULATORS
Janssen Pharmaceutica
12/10/23
-
29
COMPOUNDS FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISORDERS
1St Biotherapeutics
12/10/23
-
9
HPK1 INHIBITORS AND USES THEREOF
Qilu Regor Therapeutics
12/10/23
-
4
INDAZOLE DERIVATIVES AS CANNABINOID RECEPTOR PARTIAL AGONISTS
Research Triangle Institute
12/10/23
-
197
KRAS G12D MODULATING COMPOUNDS
Gilead Sciences
12/10/23
-
187
MACROCYCLIC HETEROCYCLES AND USES THEREOF
Kumquat Biosciences
12/10/23
-
59
MODULATORS OF ALPHA-1 ANTITRYPSIN
Vertex Pharmaceuticals
12/10/23
-
19
NOVEL PHARMACOLOGICAL CHAPERONE COMPOUNDS OF HUMAN ACID ALPHA-GLUCOSIDASE AND THE THERAPEUTIC USE THEREOF
UniversitÉ
12/10/23
-
60
SHP2 INHIBITOR AND COMPOSITION AND APPLICATION THEREOF
Betta Pharmaceuticals
12/10/23
-
555
STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS
Asteroid Therapeutics
12/10/23
-
54
SUBSTITUTED 1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS AND METHODS OF USE THEREOF
Bayer Aktiengesellschaft
12/10/23
-
128
URACIL DERIVATIVES AS MER-AXL INHIBITORS
Bristol-Myers Squibb
12/10/23
-
37
Compounds and pharmaceutical uses thereof
SyneuRx International (Taiwan)
12/05/23
-
9
Compounds for the treatment of SARS
Purdue Research Foundation
12/05/23
-
97
MAP4K4 inhibitors
Imperial College Innovations
12/05/23
-
122
Pyrrolotriazinones and imidazotriazinones as ubiquitin-specific protease 7 inhibitors
Valo Health
12/05/23
-
30
Substituted pyridines as PARP1 inhibitors
Xinthera
12/05/23
-
51
Tetrahydro-benzoazepine glycosidase inhibitors
Asceneuron
12/05/23
-
3
Uses of a lysyl oxidase-like 2 inhibitor
Pharmakea
12/05/23
-
78
AROMATIC ETHYLENE COMPOUND AND PREPARATION METHOD THEREFOR, AND INTERMEDIATE, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF
Guangzhou Maxinovel Pharmaceuticals
12/01/23
-
1
INDOLO HEPTAMYL OXIME ANALOG CRYSTAL AS PARP INHIBITOR AND METHOD FOR PREPARING SAME
Chia Tai Tianqing Pharmaceutical Group
12/01/23
-
73
INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY
University of Virginia Patent Foundation
12/01/23
-
1
N-((1-BENZYLPIPERIDIN-3-YL)METHYL)-N-(2-METHOXYETHYL)NAPHTHALENE-2-SULFONAMIDE FOR THE TREATMENT OF CANINE COGNITIVE DYSFUNCTION AND OTHER FORMS OF DEMENTIA IN DOGS
Univerza V Ljubljani
12/01/23
-
7
NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS
Enanta Pharmaceuticals
12/01/23
-
15
Pyrazolopyridine Compounds and Methods of Inhibiting IRE1 Using Same
Optikira
12/01/23
-
18
5-[[4-[[morpholin-2-yl]methylamino]-5-(trifluoromethyl)-2 Pyridyl]Amino]Pyrazine-2-carbonitrile and therapeutic uses thereof
Cancer Research Technology
11/29/23
-
165
Aryl piperidines as monoacylglycerol lipase modulators
Janssen Pharmaceutica
11/29/23
-
79
Compound having PD-L1 inhibitory activity, preparation method therefor and use thereof
Shanghai Ennovabio Pharmaceuticals
11/29/23
-
142
Diacylglyceride O-acyltransferase 2 inhibitors
Merck Sharp & Dohme
11/29/23
-
157
Dihydrobenzimidazolones for medical treatment
C4 Therapeutics
11/29/23
-
7
Inhibiting ataxia telangiectasia and RAD3-related protein (ATR)
Celator Pharmaceuticals
11/29/23
-
94
Inhibitors of VAP-1
Acucela
11/29/23
-
2
Isoquinolinyl triazolone complexes
Takeda Pharmaceutical
11/29/23
-
8
Methods of inhibiting cyclooxygenase
King Faisal University
11/29/23
-
150
Plasma Kallikrein inhibitors and uses thereof
Takeda Pharmaceutical
11/29/23
-
46
Pyrazolopyrimidine compounds as adenosine receptor antagonists
Exscientia
11/29/23
-
255
Quaternary indazole glucocorticoid receptor antagonists
Corcept Therapeutics
11/29/23
-
2
Solid forms of an HPK1 inhibitor
Incyte
11/29/23
-
34
Substituted pyrazolo[4,3-d]pyrimidines and imidazo[5,1 -f][1,2,4]triazines as androgen receptor and phosphodiesterase dual inhibitors
Ildong Pharmaceutical
11/29/23
-
46
Therapeutic compounds and methods of use
Genentech
11/29/23
-
27
ARYL PHOSPHOROUS OXIDE COMPOUNDS AND USE THEREOF
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
11/22/23
-
137
ARYL SUBSTITUTED PYRROLO-PYRIDINONES AND THERAPEUTIC USES THEREOF
Bayer Aktiengesellschaft
11/22/23
-
85
BROAD SPECTRUM ANTI-CANCER COMPOUNDS
The Regents of The University of California
11/22/23
-
14
CDK9 INHIBITORS
Biolexis Therapeutics
11/22/23
-
3
COMBINATION THERAPY
Pfizer
11/22/23
-
5
FUSED IMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF
Jiangsu Hengrui Medicine
11/22/23
-
37
FUSED TRICYCLIC DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF
Chia Tai Tianqing Pharmaceutical Group
11/22/23
-
32
HETEROAROMATIC RING COMPOUND AS RET KINASE INHIBITOR, AND PREPARATION AND USE THEREOF
Jiangsu Chia Tai Fenghai Pharmaceutical
11/22/23
-
29
IMIDAZOTRIAZINE AND PYRROLOPYRIMIDINE DERIVATIVES AS KRAS G12C INHIBITORS
Beigene
11/22/23
-
326
NEUROACTIVE STEROIDS AND THEIR METHODS OF USE
Sage Therapeutics
11/22/23
-
32
NOVEL BIARYL DERIVATIVE USEFUL AS DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR, AND USE THEREOF
Lg Chem
11/22/23
-
178
OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF
Eikonizo Therapeutics
11/22/23
-
174
PYRAZOLOPYRIDAZINONE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
Broadenbio
11/22/23
-
16
TRIAZOLE DERIVATIVES AND THEIR USE AS TANKYRASE INHIBITORS
Oslo Universitetssykehus
11/22/23
-
9
UNIT DOSAGE COMPOSITION OF AKT INHIBITOR
Nanjing Chia Tai Tianqing Pharmaceutical
11/22/23
-
1441
FGFR inhibitors and methods of use thereof
Relay Therapeutics
11/17/23
-
253
Imino sulfanone inhibitors of ENPP1
Volastra Therapeutics
11/17/23
-
56
LRRK2 inhibitors
H. Lundbeck
11/17/23
-
281
Methods for treating Crohn's disease using 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile
Theravance Biopharma R&D Ip
11/17/23
-
57
Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors
Orsobio
11/17/23
-
15
Prolyl hydroxylase domain-containing protein (PHD) inhibitors and uses thereof
Insilico Medicine Ip
11/17/23
-
20
Pyridinamine-pyridone and pyrimidinamine-pyridone compounds
Sprint Bioscience
11/17/23
-
46
Substituted 3-phenoxyazetidin-1-yl-pyrazines
Boehringer Ingelheim International
11/17/23
-
93
Substituted N-pyrimidin-4-yl-3-aminopyrrolo[3,4-C]pyrazoles as protein kinase C inhibitors
Pfizer
11/17/23
-
34
TYK2 pseudokinase ligands
Ventyx Biosciences
11/17/23
-
9
1-(5-(2-CYANOPYRIDIN-4-YL)OXAZOLE-2-CARBONYL)-4-METHYLHEXAHYDROPYRROLO[3,4-B]PYR ROLE-5(1H)-CARBONITRILE AS USP30 INHIBITOR FOR USE IN THE TREATMENT OF MITOCHONDRIAL DYSFUNCTION, CANCER AND FIBROSIS
Mission Therapeutics
11/13/23
-
21
1H-IMIDAZO [4,5-H] QUINAZOLINE COMPOUND AS NOVEL SELECTIVE FLT3 INHIBITORS
Shengke Pharmaceuticals (Jiangsu)
11/13/23
-
176
2-OXO-IMIDAZOLIDINE-4-CARBOXAMIDES AS NAV1.8 INHIBITORS
Merck Sharp & Dohme
11/13/23
-
118
4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-3,6-DIHYDROPYRIDINE-1-(2H)-CARBOXAMIDE DERIVATIVES AS LIMK AND/OR ROCK KINASES INHIBITORS FOR USE IN THE TREATMENT OF CANCER
Centre National De La Recherche Scientifique
11/13/23
-
87
ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Sichuan Kelun-Biotech Biopharmaceutical
11/13/23
-
27
COMPOUNDS WITH SEMIOCHEMICAL PROPERTIES AND BIOSENSORS
Rothamsted Research
11/13/23
-
51
CYP46A1 INHIBITORS AND METHODS OF USE THEREOF
Sage Therapeutics
11/13/23
-
67
HYDROXYPYRROLIDINE DERIVATIVE AND MEDICINAL APPLICATION THEREOF
Mitsubishi Tanabe Pharma
11/13/23
-
229
N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)-QUINOLINE-4-CARBOXAMIDES
Astrazeneca
11/13/23
-
46
PTERIDINONE COMPOUNDS AND USES THEREOF
Vertex Pharmaceuticals
11/13/23
-
13
PYRIMIDINE SMALL-MOLECULE COMPOUND AND APPLICATION THEREOF
Wenzhou Medical University
11/13/23
-
236
PYRROLO[2,1-F][1,2,4]TRIAZINES AND PREPARATION AND USES THEREOF
Biosplice Therapeutics
11/13/23
-
1
QUINOLINE COMPOUNDS
Guangzhou Baiyunshan Pharmaceutical Holdings Co., Ltd. Baiyunshan Pharmaceutical General Factory
11/13/23
-
12
RING-MODIFIED PROLINE SHORT PEPTIDE COMPOUND AND USE THEREOF
Fujian Akeylink Biotechnology
11/13/23
-
2
Salts Of Nitrogen-Containing Heterocyclic Compound, And Solid Forms Of Salts, Pharmaceutical Composition And Use Thereof
Wuhan Humanwell Innovative Drug Research and Development Center
11/13/23
-
39
THIAZOLO[5,4-B]PYRIDINE MALT-1 INHIBITORS
Abbvie
11/13/23
-
396
Furin inhibitors
Glaxosmithkline Intellectual Property Development
11/07/23
-
84
Methods and compounds for treating disorders
Foghorn Therapeutics
11/07/23
-
8
Substituted pyridines as DNMT1 inhibitors
Glaxosmithkline Intellectual Property Development
11/07/23
-
258
2-AMINOQUINAZOLINES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF
Merck Sharp & Dohme
11/06/23
-
59
4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE SUMO INHIBITORS AND USES THEREOF
Suvalent Therapeutics
11/06/23
-
39
BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF
Academy of Military Medical Sciences
11/06/23
-
9
BENZYLAMINE OR BENZYL ALCOHOL DERIVATIVE AND USES THEREOF
Chengdu Hyperway Pharmaceuticals
11/06/23
-
53
CDK6/DYRK2 DUAL-TARGET INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Jiangsu Tasly Diyi Pharmaceutical
11/06/23
-
5
COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF MITOCHONDRIAL DISEASE, INCLUDING FRIEDREICH'S ATAXIA
Stealth Biotherapeutics
11/06/23
-
1
CRYSTALLINE FORM OF TLR8 AGONIST
Chia Tai Tianqing Pharmaceutical Group
11/06/23
-
91
MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF
Children'S Hospital Medical Center
11/06/23
-
12
N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS
Mission Therapeutics
11/06/23
-
2
ORALLY BIOAVAILABLE, BRAIN-PENETRANT COMPOUND WITH SELECTIVITY FOR THE CANNABINOID TYPE 2 RECEPTOR WITH POTENTIAL USE TOWARDS VISCERAL PAIN MANAGEMENT AND NEURODEGENERATIVE DISORDERS
University of Mississippi
11/06/23
-
73
OXOPYRROLIDINE UREA FPR2 AGONISTS
Bristol-Myers Squibb
11/06/23
-
13
PIPERAZINE SUBSTITUTED INDAZOLE COMPOUNDS AS INHIBITORS OF PARG
Ideaya Biosciences
11/06/23
-
11
PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF
Sichuan Kelun-Biotech Biopharmaceutical
11/06/23
-
13
PYRIMIDINE RING COMPOUND
Medshine Discovery
11/06/23
-
13
Advantageous benzofuran compositions for mental disorders or enhancement
Tactogen
11/02/23
-
43
Glucose-sensitive albumin-binding derivatives
Novo Nordisk
11/02/23
-
18
Nicotinamide RIPK1 inhibitors
Abbvie
11/02/23
-
44
Tricyclic pyridone compounds as JAK2 V617F inhibitors
Incyte
11/02/23
-
357
3-(1H-IMIDAZOL-2-YL)-2,3,8,8A-TETRAHYDROINDOLIZIN-5(1H)-ONE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS
Janssen Pharmaceutica
10/30/23
-
258
ANTAGONIST COMPOUNDS
Adorx Therapeutics
10/30/23
-
47
ATR INHIBITORS AND USES THEREOF
Antengene Discovery
10/30/23
-
29
ATX INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Suzhou Ark Biopharmaceutical
10/30/23
-
32
CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF
Risen (Suzhou) Pharma Tech
10/30/23
-
170
COMPOUND USEFUL AS CDK7 KINASE INHIBITOR AND USE THEREOF
Tyk Medicines
10/30/23
-
128
FUSED HETEROAROMATIC PYRROLIDINONES
Calithera Biosciences
10/30/23
-
6
INHIBITOR OF APOPTOSIS (IAP) PROTEIN ANTAGONISTS
Sanford Burnham Prebys Medical Discovery Institute
10/30/23
-
94
INHIBITORS OF VAP-1
Acucela
10/30/23
-
137
INTEGRIN INHIBITORS AND USES THEREOF IN COMBINATION WITH OTHER AGENTS
Pliant Therapeutics
10/30/23
-
36
NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
Chong Kun Dang Pharmaceutical
10/30/23
-
67
PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE
Akebia Therapeutics
10/30/23
-
115
SPIRO DERIVATIVES OF ALPHA-D-GALACTOPYRANOSIDES
Idorsia Pharmaceuticals
10/30/23
-
329
SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATORY DISEASES
Gossamer Bio Services
10/30/23
-
44
Carboxylic acid, acyl sulfonamide and acyl sulfamide-derivatized bicyclic aza-heteroaromatics as selective Mcl-1 inhibitors and as dual Mcl-1/Bcl-2 inhibitors
University of Maryland, Baltimore
10/29/23
-
75
Methods and compositions for targeting PD-L1
Aligos Therapeutics
10/29/23
-
9
Steroids and protein-conjugates thereof
Regeneron Pharmaceuticals
10/29/23
-
11
TKI permeability enhancers
City of Hope
10/29/23
-
59
1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDINE-4-ON AND DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR PREVENTING, ALLEVIATING OR TREATING NEURODEGENERATIVE DISEASES
Duksung Women''S University Industry-Academic Cooperation Foundation
10/23/23
-
96
ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE
Petra Pharma
10/23/23
-
120
BCL6 INHIBITORS
Cancer Research Technology
10/23/23
-
56
HALOALKYLPYRIDYL TRIAZOLE MLL1-WDR5 PROTEIN-PROTEIN INTERACTION INHIBITOR
Huyabio International
10/23/23
-
139
IL-17A MODULATORS
Sanofi
10/23/23
-
13
INDAZOLE DERIVATIVES AS INHIBITORS OF SARM1
Disarm Therapeutics
10/23/23
-
238
ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF
Biosplice Therapeutics
10/23/23
-
47
KCNT1 INHIBITORS AND METHODS OF USE
Praxis Precision Medicines
10/23/23
-
10
METHOD FOR TREATING GRAFT VERSUS HOST DISEASE CAUSED BY HEMATOPOIETIC STEM CELL TRANSPLANTATION
Beijing Tide Pharmaceutical
10/23/23
-
58
NEPRILYSIN INHIBITORS
Theravance Biopharma R&D Ip
10/23/23
-
417
NOVEL OXADIAZOLE-BASED SELECTIVE HDAC6 INHIBITORS
Italfarmaco
10/23/23
-
33
PHENYL TRIAZOLE MLL1-WDR5 PROTEIN-PROTEIN INTERACTION INHIBITOR
Huyabio International
10/23/23
-
185
PLASMA KALLIKREIN INHIBITORS
Merck Sharp & Dohme
10/23/23
-
32
QUINAZOLINONE HSD17B13 INHIBITORS AND USES THEREOF
Inipharm
10/23/23
-
3
SALT OF DIHYDROPYRIDO[2,3-D]PYRIMIDINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF
Nanjing Chia Tai Tianqing Pharmaceutical
10/23/23
-
30
Disulfiram derivatives as ALDH1A1 and MAGL inhibitors
Batterjee Medical College
10/20/23
-
295
EIF4E inhibitors and uses thereof
Pic Therapeutics
10/20/23
-
34
Muscarinic acetylcholine M1 receptor antagonists
Pipeline Therapeutics
10/20/23
-
55
Protease inhibitors as antivirals
Acea Therapeutics
10/20/23
-
137
Treating primary or idiopathic hyperoxaluria with small molecule inhibitors of lactate dehydrogenase
Vanderbilt University
10/20/23
-
57
Treatment of autism spectrum disorders, obsessive-compulsive disorder and anxiety disorders
Rugen Holdings (Cayman)
10/20/23
-
187
DICHLOROPHENOL HSD17B13 INHIBITORS AND USES THEREOF
Inipharm
10/18/23
-
54
Benzimidazole Derivative Compounds and Uses Thereof
Pfizer
10/17/23
-
1030
CARM1 INHIBITORS AND USES THEREOF
Epizyme
10/17/23
-
37
CERTAIN (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS
Astrazeneca
10/17/23
-
207
COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR
Plexxikon
10/17/23
-
143
Compound containing structure of a five-membered heteroaromatic ring, pharmaceutical compositions thereof and applications thereof
280 Bio
10/17/23
-
5
DIARYL AND ARYLHETEROARYL UREA DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO
Arena Pharmaceuticals
10/17/23
-
34
ENPP1 Inhibitors and Their Use for the Treatment of Cancer
The Board of Trustees of The Leland Stanford Junior University
10/17/23
-
4
IMIDAZO[1,2-A]PYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE
Hoffmann-La Roche
10/17/23
-
90
INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER
Universite Claude Bernard Lyon 1
10/17/23
-
461
KRAS G12D INHIBITORS
Mirati Therapeutics
10/17/23
-
160
N/O-Linked Degrons and Degronimers for Protein Degradation
C4 Therapeutics
10/17/23
-
7
NOVEL TRICYCLIC AROMATIC HETEROCYCLIC COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF
Shanghai Longwood Biopharmaceuticals
10/17/23
-
26
PTGR2 INHIBITORS AND THEIR USE
National Health Research Institutes
10/17/23
-
20
ROR-GAMMA MODULATORS
Escalier Biosciences
10/17/23
-
29
TRIAZINE COMPOUND AND COMPOSITION AND USE THEREOF
Beijing Findcure Biosciences
10/17/23
-
188
YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS
Molecure
10/17/23
-
98
5-AMINO-8-(4-PYRIDYL)-[1,2,4]TRIAZOLO[4,3-C]PYRIMIDIN-3-ONE COMPOUNDS FOR USE AGAINST CANCER
Astrazeneca
10/16/23
-
100
AMIDE DERIVATIVES
Merck Patent
10/16/23
-
144
AMINO ACID COMPOUNDS AND METHODS OF USE
Pliant Therapeutics
10/16/23
-
44
COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF
Ono Pharmaceutical
10/16/23
-
549
COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE
Vertex Pharmaceuticals
10/16/23
-
250
COMPOUNDS USEFUL AS T CELL ACTIVATORS
Gossamer Bio Services
10/16/23
-
20
CONDENSED PYRAZOLE DERIVATIVES AS INHIBITORS OF SARM1
Disarm Therapeutics
10/16/23
-
5
PRPK INHIBITORS
Dana-Farber Cancer Institute
10/16/23
-
24
PYRAZOLOPYRIMIDINE COMPOUND USED AS ATR KINASE INHIBITOR
Beijing Tide Pharmaceutical
10/16/23
-
3
SALT AND CRYSTAL FORM OF DIHYDROPYRIDO[2,3-d]PYRIMIDINE DERIVATE
Nanjing Chia Tai Tianqing Pharmaceutical
10/16/23
-
42
4-ETHYNYLPYRIDINE DERIVATIVES USEFUL AS GCN2 INHIBITORS
Ip2Ipo Innovations
10/15/23
-
210
BENZODIAZEPINE DERIVATIVES USEFUL IN TREATING A RESPIRATORY SYNCYTIAL VIRUS INFECTION
Reviral
10/15/23
-
164
CARBOXYLIC ACID AROMATIC AMIDES AS ANTAGONISTS OF BRADYKININ B1 RECEPTOR
Bayer Pharma Aktiengesellschaft
10/15/23
-
176
COMPOSITION CONTAINING ARYLAMIDE DERIVATIVE
Chugai Seiyaku Kabushiki Kaisha
10/15/23
-
124
COMPOUNDS ACTIVE TOWARDS NUCLEAR RECEPTORS
Nuevolution
10/15/23
-
76
COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY
Ifm Due
10/15/23
-
412
GLP-1R MODULATING COMPOUNDS
Ascletis Bioscience
10/15/23
-
129
INHIBITORS OF APOL1 AND METHODS OF USING SAME
Vertex Pharmaceuticals
10/15/23
-
135
SUBSTITUTED PYRROLIZINE COMPOUNDS AND USES THEREOF
Gilead Sciences
10/15/23
-
162
2-amino-3-carbonyl imidazopyridine and pyrazolopyridine compounds
1St Biotherapeutics
10/06/23
-
56
ALK-5 inhibitors and uses thereof
Sumitomo Pharma Oncology
10/06/23
-
16
Alkynyl (hetero) aromatic ring compounds used for inhibiting protein kinase activity
Shenzhen Targetrx
10/06/23
-
43
Labelled cannabinergic ligands and related analogs
Individual
10/06/23
-
10
Method of increasing platelet counts of a subject
Korea Basic Science Institute
10/06/23
-
31
Acetamido-phenyltetrazole derivatives and methods of using the same
Athenex
10/01/23
-
125
Methods of inhibiting kinases
Insilico Medicine Ip
10/01/23
-
22
Small molecule inhibitors of ubiquitin specific protease 1 (USP1) and uses thereof
Insilico Medicine Ip
10/01/23
-
10
Substituted pyrazlo[3,4-c]pyridines as selective BTK kinase inhibitors
Jumbo Drug Bank
10/01/23
-
5
Substituted pyrazolopyrazines, imidazopyrazines and [1,2,4]triazolopyrazines as allosteric SHP2 inhibitors
Revolution Medicines
10/01/23
-
105
Carboxamide compounds and uses thereof
Incyte
09/26/23
-
36
Histone demethylase inhibitors
Celgene Quanticel Research
09/26/23
-
47
N-acyl-(3-substituted)-(8-substituted)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists
Ogeda
09/26/23
-
93
SARS-CoV-2 inhibitors for treating coronavirus infections
Insilico Medicine Ip
09/26/23
-
58
Spiro compounds as glycosidase inhibitors
Asceneuron
09/26/23
-
106
Substituted 1,2,4-triazoles as intermediates in the synthesis of TYK2 inhibitors
Alumis
09/26/23
-
31
Substituted pyrazolo[3,4-d]pyrimidines as mTOR inhibitors
Galderma Research & Development
09/26/23
-
41
HDAC inhibitor compounds and methods of treatment
University of Florida Research Foundation
09/25/23
-
298
Therapeutic compounds, compositions and methods of use thereof
Genentech
09/25/23
-
20
(Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles
Centrexion Therapeutics
09/23/23
-
253
Bicyclic compound and use thereof
Sk Biopharmaceuticals
09/23/23
-
3
Bicyclic urea kinase inhibitors and uses thereof
The General Hospital
09/23/23
-
43
Compositions and methods for inhibiting kinases
Inhibikase Therapeutics
09/23/23
-
151
Polyheterocyclic compounds as METTL3 inhibitors
Storm Therapeutics
09/23/23
-
415
Apoptosis inhibitors
National Institute of Biological Sciences, Beijing
09/21/23
-
176
Compounds and compositions for treating conditions associated with NLRP activity
Novartis
09/21/23
-
80
MCT4 inhibitors for treating disease
Vettore
09/21/23
-
49
Methods of improving cell-based therapy
The Regents of The University of California
09/21/23
-
52
Quinazoline derivatives as antitumor agents
Suzhou Zanrong Pharma
09/21/23
-
222
Heterocyclic adenosine receptor antagonists
Exelixis
09/17/23
-
63
Isoxazolyl-carbonyloxy azabicyclo[3.2.1]octanyl compounds as FXR activators
Ardelyx
09/17/23
-
27
JAK kinase inhibitor compounds for treatment of respiratory disease
Theravance Biopharma R&D Ip
09/17/23
-
19
N-(phenylsulfonyl)benzamides and related compounds as Bcl-2 inhibitors
The Regents of The University of Michigan
09/17/23
-
106
Substituted pyrido[2,1-a]isoquinolines as VMAT2 inhibitors
Neurocrine Biosciences
09/17/23
-
1
Benzenesulfonylbenazamide compound for inhibiting BCL-2 protein and composition and use thereof
Shenzhen Targetrx
09/15/23
-
570
CDK2 inhibitors
Pfizer
09/15/23
-
164
Compositions and methods of modulating short-chain dehydrogenase
Case Western Reserve University
09/15/23
-
25
Heparanase inhibitors and use thereof
Beta Therapeutics
09/15/23
-
13
Heterocyclic compounds as immunomodulators
Incyte
09/15/23
-
70
Inhibitors of receptor interacting protein kinase I for the treatment of disease
Board of Regents, The University of Texas System
09/15/23
-
3
Treatment of spondyloarthritis
Pharmacyl
09/15/23
-
107
Azole derivatives as apelin receptor agonist
Sanford Burnham Prebys Medical Discovery Institute
09/08/23
-
5
Bismuth(III) compounds and methods thereof
The University of Hong Kong
09/08/23
-
3
Crystal form, salt type of substituted 2-hydro-pyrazole derivative and preparation method therefor
Chia Tai Tianqing Pharmaceutical Group
09/08/23
-
187
Cyanotriazole compounds
Otsuka Pharmaceutical
09/08/23
-
9
Heterocyclic indoles for use in influenza virus infection
Janssen Sciences Ireland Uc
09/08/23
-
420
Heterocyclic sulfonamide derivative and medicine comprising same
Ea Pharma
09/08/23
-
117
Inhibitor of lysine specific demethylase-1
Celgene Quanticel Research
09/08/23
-
332
Inhibitors of low molecular weight protein tyrosine phosphatase and uses thereof
Sanford Burnham Prebys Medical Discovery Institute
09/08/23
-
42
Peptide derivatives and uses thereof
Nosopharm
09/08/23
-
14
Phosphodiesterase inhibitors and uses thereof
The Trustees of Columbia University In The City of New York
09/08/23
-
216
2,4,5-trisubstituted 1,2,4-triazolones useful as inhibitors of DHODH
Bayer Aktiengesellschaft
09/04/23
-
12
5 to 7 membered heterocyclic amides as JAK inhibitors
Theravance Biopharma R&D Ip
09/04/23
-
143
5-heteroaryl substituted indazole-3-carboxamides and preparation and use thereof
Biosplice Therapeutics
09/04/23
-
39
5-substituted difluoropiperidine compounds with blood-brain barrier penetrable capability
Wayshine Biopharm Holding
09/04/23
-
44
GSK-3 inhibitors
Bristol-Myers Squibb
09/04/23
-
26
Heteroaryl heterocyclyl compounds for the treatment of autoimmune disease
Hoffmann-La Roche
09/04/23
-
102
Heteroaryl-biphenyl amides for the treatment of PD-L1 diseases
Chemocentryx
09/04/23
-
44
Inhibitors of NEK7 kinase
Halia Therapeutics
09/04/23
-
218
Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1
Cancer Research Technology
08/31/23
-
44
Hydroxyalkyl-piperazine derivatives as CXCR3 receptor modulators
Idorsia Pharmaceuticals
08/31/23
-
267
Protein kinase modulators
Cylene Pharmaceuticals
08/31/23
-
563
Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders
Achillion Pharmaceuticals
08/27/23
-
92
Azaindole derivatives and their use as ERK kinase inhibitors
Agv Discovery
08/27/23
-
30
Compounds for the treatment of kinase-dependent disorders
Exelixis
08/27/23
-
34
ENPP1 inhibitors and their use for the treatment of cancer
The Board of Trustees of The Leland Stanford Junior University
08/27/23
-
89
FAP-targeted radiopharmaceuticals and imaging agents, and uses related thereto
Trustees of Tufts College
08/27/23
-
34
Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof
Novartis
08/27/23
-
250
Human plasma kallikrein inhibitors
Biocryst Pharmaceuticals
08/27/23
-
410
Immunomodulator compounds
Chemocentryx
08/27/23
-
122
Monoacylglycerol lipase modulators
Janssen Pharmaceutica
08/27/23
-
536
Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors
Biocryst Pharmaceuticals
08/27/23
-
98
1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins
Incyte
08/18/23
-
364
Bicyclic-fused heteroaryl or aryl compounds
Pfizer
08/18/23
-
8
Composition for inducing differentiation and protection of neural stem cells and method for inducing neuro-regeneration using the same composition
Genuv
08/18/23
-
36
Compounds and methods of use
Medivation Technologies
08/18/23
-
2
Crystalline hydrate of a JAK inhibitor compound
Theravance Biopharma R&D Ip
08/18/23
-
34
ENPP1 inhibitors and their use for the treatment of cancer
The Board of Trustees of The Leland Stanford Junior University
08/18/23
-
42
Pyrazolo[3,4-b]pyrazine derivatives as SHP2 phosphatase inhibitors
D. E. Shaw Research
08/18/23
-
94
Pyrazolyl derivatives useful as anti-cancer agents
Novartis
08/18/23
-
34
Pyridine, pyrazine, and triazine compounds as allosteric SHP2 inhibitors
Revolution Medicines
08/18/23
-
143
Pyrimidinone derivatives as SHP2 antagonists
Merck Patent
08/18/23
-
365
SOS1 inhibitors
Mirati Therapeutics
08/18/23
-
9
Substituted bicyclic compounds
Bristol-Myers Squibb
08/18/23
-
303
Thiadiazole IRAK4 inhibitors
Gilead Sciences
08/18/23
-
79
Agent enhancing antitumor effect using pyrazolo[3,4-d]pyrimidine compound
Taiho Pharmaceutical
08/11/23
-
100
Carboxamide-pyrimidine derivatives as SHP2 antagonists
Merck Patent
08/11/23
-
42
Compounds having tetrahydroindolizine-1-carboxamide as BCL-2 inhibitors
Eil Therapeutics
08/11/23
-
264
Fused pyrimidine pyridinone compounds as JAK inhibitors
Theravance Biopharma R&D Ip
08/11/23
-
318
Substituted benzamides
Hoffmann-La Roche
08/11/23
-
15
2-[thiophen-2-yl)formamido]-N-(phenyl)-2-methylpropanamide derivatives and the use thereof as medicament
Boehringer Ingelheim International
08/06/23
-
234
6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors
Ajax Therapeutics
08/06/23
-
44
Compound having KDM5 inhibitory activity and pharmaceutical use thereof
Ono Pharmaceutical
08/06/23
-
82
Cyclic ether derivatives of pyrazolo[1,5-A]pyrimidine-3-carboxyamide
Boehringer Ingelheim International
08/06/23
-
80
Heterocyclic compounds, preparation methods therefor, and methods of uses thereof
Inventisbio
08/06/23
-
101
Inhibitors of receptor interacting protein kinase I for the treatment of disease
Board of Regents, The University of Texas System
08/06/23
-
93
Isoindoline compositions and methods for treating neurodegenerative disease
Cognition Therapeutics
08/06/23
-
21
Isoquinoline-steroid conjugates and uses thereof
Aerie Pharmaceuticals
08/06/23
-
25
MAGL inhibitors
H. Lundbeck
08/06/23
-
25
Macrocyclic immunomodulators
Chemocentryx
08/06/23
-
51
Macrocyclic indoles as Mcl-1 inhibitors
Ascentage Pharma (Suzhou)
08/06/23
-
1
Method for preparing pyrrolidinyl urea derivative
Zhangzhou Pien Tze Huang Pharmaceutical
08/06/23
-
24
Naphthyridinone compounds as JAK2 V617F inhibitors
Incyte
08/06/23
-
96
Pyridazinones as PARP7 inhibtors
Ribon Therapeutics
08/06/23
-
217
Therapeutic compounds and compositions
Exithera Pharmaceuticals
08/06/23
-
121
ATM kinase inhibitors and compositions and methods of use thereof
Chdi Foundation
07/31/23
-
106
Azalactam compounds as HPK1 inhibitors
Pfizer
07/31/23
-
82
C5a receptor modulators
Idorsia Pharmaceuticals
07/31/23
-
123
CDK inhibitors and their use as pharmaceuticals
Prelude Therapeutics
07/31/23
-
14
Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof
Ocuterra Therapeutics
07/31/23
-
245
Human plasma kallikrein inhibitors
Biocryst Pharmaceuticals
07/31/23
-
491
MYST family histone acetyltransferase inhibitors
Epizyme
07/31/23
-
24
Pyridinone MK2 inhibitors and uses thereof
Xinthera
07/31/23
-
385
Substituted benzoxazole and benzofuran compounds as PDE7 inhibitors
Dart Neuroscience
07/31/23
-
138
Bicycloheptane pyrrolidine orexin receptor agonists
Merck Sharp & Dohme
07/25/23
-
37
Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides as dipeptidyl peptidase 1 inhibitors
Astrazeneca
07/25/23
-
22
Compounds and compositions as protein kinase inhibitors
Array Biopharma
07/25/23
-
55
Compounds useful as RET inhibitors
Cancer Research Technology
07/25/23
-
82
MK2 inhibitors and uses thereof
Xinthera
07/25/23
-
2
Methods of treating disorders using CSF1R inhibitors
Deciphera Pharmaceuticals
07/25/23
-
16
Substituted aminobenzyl heteroaryl compounds as EGFR and/or PI3K inhibitors
Mekanistic Therapeutics
07/19/23
-
155
5-membered and bicyclic heterocyclic amides as inhibitors of ROCK
Bristol-Myers Squibb
07/16/23
-
40
Amino pyrimidine derivatives
Novartis
07/16/23
-
17
Bicyclic compounds as ATX inhibitors
Hoffmann-La Roche
07/16/23
-
88
CDK inhibitors and their use as pharmaceuticals
Prelude Therapeutics
07/16/23
-
35
Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides as dipeptidyl peptidase 1 inhibitors
Astrazeneca
07/16/23
-
11
Compounds for the treatment of kinase-dependent disorders
Exelixis
07/16/23
-
51
Heterocyclic compounds as immunomodulators
Incyte
07/16/23
-
13
Histone deacetylase inhibitors for immunomodulation in tumor microenvironment
Great Novel Therapeutics Biotech & Medicals
07/16/23
-
96
Imidazopyrimidines and triazolopyrimidines as A2A / A2B inhibitors
Incyte
07/16/23
-
303
Isoquinolin-3-yl carboxamides and preparation and use thereof
Biosplice Therapeutics
07/16/23
-
12
Matrix metalloproteinase (MMP) inhibitors and methods of use thereof
Foresee Pharmaceuticals
07/16/23
-
21
Pharmaceutical compounds
Sareum
07/16/23
-
82
Polycyclic compounds as allosteric SHP2 inhibitors
Revolution Medicines
07/16/23
-
159
Pyridone amides as modulators of sodium channels
Vertex Pharmaceuticals
07/16/23
-
7
Tetrahydro-1H-pyrido [3,4-b]indole anti-estrogenic drugs
Olema Pharmaceuticals
07/16/23
-
50
4-substitued cytisine analogues
University of Bristol
07/09/23
-
7
Antibody-drug conjugates comprising a cyclic dinucleotide
Takeda Pharmaceutical
07/09/23
-
37
Bicyclic heterocycles as FGFR4 inhibitors
Incyte
07/09/23
-
36
Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides as dipeptidyl peptidase 1 inhibitors
Astrazeneca
07/09/23
-
378
Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators
Janssen Pharmaceutica
07/09/23
-
56
FGFR4 inhibitor, preparation method therefor, and applications thereof
Jiangsu Hansoh Pharmaceutical Group
07/09/23
-
11
Fused imidazo-piperidine JAK inhibitors
Theravance Biopharma R&D Ip
07/09/23
-
148
Granzyme B directed imaging and therapy
Cytosite Biopharma
07/09/23
-
65
Inhibitors of RAF kinases
Kinnate Biopharma
07/09/23
-
204
MCL1 inhibitors
Gilead Sciences
07/09/23
-
97
Methods of treating intraocular pressure with activators of Tie-2
Eyepoint Pharmaceuticals
07/09/23
-
80
RIP1K inhibitors
Rigel Pharmaceuticals
07/09/23
-
206
Therapeutically active compounds and their methods of use
Servier Pharmaceuticals
07/09/23
-
86
Heterocyclic compounds as RET kinase inhibitors
Cancer Research Technology
07/03/23
-
496
Imidazole-containing inhibitors of ALK2 kinase
Biocryst Pharmaceuticals
07/03/23
-
18
Tetrazole derivatives as TRPA1 inhibitors
Boehringer Ingelheim International
07/03/23
-
8
Thienopyrrole compounds
Gilead Sciences
07/03/23
-
26
Tricyclic urea compounds as JAK2 V617F inhibitors
Incyte
07/03/23
-
54
Benzimidazole derivative compounds and uses thereof
Pfizer
07/02/23
-
13
MASP-2 inhibitors and methods of use
Omeros
07/02/23
-
129
Substituted 2-azabicyclo[3.1.1]heptane and 2-azabicyclo[3.2.1]octane derivatives as orexin receptor antagonists
Chronos Therapeutics
07/02/23
-
28
Treatment of Rett syndrome
Cold Spring Harbor Laboratory
07/02/23
-
87
Tricyclic compounds as histone methyltransferase inhibitors
Global Blood Therapeutics
07/02/23
-
170
ALK2 inhibitors and methods for inhibiting BMP signaling
The Brigham and Women'S Hospital
06/26/23
-
4
Aminopyrimidinyl derivatives
Pfizer
06/26/23
-
37
Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides as dipeptidyl peptidase 1 inhibitors
Astrazeneca
06/26/23
-
32
Fused ring pyrimidine amino compound and preparation method, pharmaceutical composition, and use thereof
Shanghai Institute of Material Medica, Chinese Academy of Sciences
06/26/23
-
4
Glucagon-like peptide1 receptor agonists
Eli Lilly
06/26/23
-
23
Indolizine derivatives and their application in medicine
Kind Pharmaceutical
06/26/23
-
252
Pyrazole MAGL inhibitors
H. Lundbeck
06/26/23
-
32
Pyridine and pyrazine derivatives as preferential cannabinoid 2 agonists
Hoffmann-La Roche
06/26/23
-
6
Substituted piperazines as BTK inhibitors
Hutchison Medipharma
06/26/23
-
8
7-phenylethylamino-4H-pyrimido[4,5-d][1,3]oxazin-2-one compounds as mutant IDH1 and IDH2 inhibitors
Eli Lilly
06/19/23
-
98
Allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) for the treatment of disease
Petra Pharma
06/19/23
-
8
Amide compounds for treatment of immune and inflammatory disorders
Achillion Pharmaceuticals
06/19/23
-
81
C-Abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same
The United States of America, As Represented By The Secretary, Department of Health and Human Services
06/19/23
-
18
Compound as mTOR inhibitor and use thereof
Medicinal Bioconvergence Research Center
06/19/23
-
18
Halo-allylamine SSAO/VAP-1 inhibitor and use thereof
Nanjing Transthera Biosciences
06/19/23
-
663
Indazoles as hematopoietic progenitor kinase 1 (HPK1) inhibitors and methods using same
1St Biotherapeutics
06/19/23
-
113
Oxadiazaspiro compounds for the treatment of drug abuse and addiction
Esteve Pharmaceuticals
06/19/23
-
2
Pan-tropic entry inhibitors
Emory University
06/19/23
-
14
Pyrazolochlorophenyl compounds, compositions and methods of use thereof
Genentech
06/19/23
-
50
Selective androgen receptor degrader (SARD) ligands and methods of use
University of Tennessee Research Foundation
06/19/23
-
111
Substituted 4-phenylpiperidines, their preparation and use
The Trustees of Columbia University In The City of New York
06/19/23
-
228
Substituted imidazo[1,5-a]pyrazines for IRE1 inhibition
Optikira
06/19/23
-
814
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors
Array Biopharma
06/19/23
-
320
Substituted pyrido[2,3-d]pyrimidines as inhibitors of Ras pathway signaling
Kumquat Biosciences
06/19/23
-
2
5-HT2A agonists for use in treatment of depression
Lophora
06/11/23
-
156
BRD4-kinase inhibitors as cancer therapeutics
H. Lee Moffitt Cancer Center and Research Institute
06/11/23
-
8
Compounds for degrading Tau protein aggregates and uses thereof
Aprinoia Therapeutics
06/11/23
-
9
Derivatives of 4-aminoantipyrine as anti-Alzheimers butyrylcholinesterase inhibitors
Individual
06/11/23
-
11
GLP-1 receptor agonist and use thereof
Ildong Pharmaceutical
06/11/23
-
443
MCL-1 inhibitors
Gilead Sciences
06/11/23
-
10