Compile Data Set for Download or QSAR
Report error Found 693 Enz. Inhib. hit(s) with all data for entry = 9478
TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469350BDBM469350(cis-5-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  0.300nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469376BDBM469376(cis-1-(Cyclobutyl-methyl)-8-dimethylamino-8-phenyl...)
Affinity DataKi:  0.400nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469352BDBM469352(cis-5-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  0.400nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469357BDBM469357(cis-2-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  0.600nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469437BDBM469437(cis-5-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  0.600nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469382BDBM469382(cis-4-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  0.600nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469435BDBM469435(cis-1-(Cyclobutyl-methyl)-8-dimethylamino-3-(2-met...)
Affinity DataKi:  0.600nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469419BDBM469419(cis-5-[1-[(1-Cyano-cyclobutyl)-methyl]-8-dimethyla...)
Affinity DataKi:  0.700nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469354BDBM469354(cis-5-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  0.700nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469365BDBM469365(cis-2-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  0.800nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469398BDBM469398(cis-5-[1-[(1-Cyano-cyclobutyl)-methyl]-8-dimethyla...)
Affinity DataKi:  0.900nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469458BDBM469458(cis-8-Dimethylamino-1-[(1-hydroxy-cyclobutyl)-meth...)
Affinity DataKi:  1nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469378BDBM469378(cis-5-[8-Dimethylamino-1-(2-methyl-propy1)-2-oxo-8...)
Affinity DataKi:  1nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469405BDBM469405(cis-4-[1-(Cyclobuty1-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  1nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469432BDBM469432(cis-1-(Cyclobutyl-methyl)-8-dimethylamino-8-phenyl...)
Affinity DataKi:  1nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469461BDBM469461(cis-1-(Cyclobutyl-methyl)-8-dimethylamino-3-[4-met...)
Affinity DataKi:  1nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469395BDBM469395(cis-1-(Cyclobutyl-methyl)-8-methylamino-8-phenyl-3...)
Affinity DataKi:  1nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469460BDBM469460(cis-1-[(1-Hydroxy-cyclobutyl)-methyl]-8-methylamin...)
Affinity DataKi:  1nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469458BDBM469458(cis-8-Dimethylamino-1-[(1-hydroxy-cyclobutyl)-meth...)
Affinity DataKi:  1nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469708BDBM469708(US10807988, Example SC_3344 | cis-8-Dimethylamino-...)
Affinity DataKi:  1nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469764BDBM469764(US10807988, Example SC_3401 | cis-1-(Cyclobutyl-me...)
Affinity DataKi:  1nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469459BDBM469459(cis-1-[(1-Hydroxy-cyclobutyl1)-methyl]-8-methylami...)
Affinity DataKi:  1nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469358BDBM469358(cis-2-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  1.10nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469355BDBM469355(cis-5-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  1.10nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469445BDBM469445(cis-1-(Cyclobutyl-methyl)-3-(2,4-dimethoxy-phenyl)...)
Affinity DataKi:  1.10nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469452BDBM469452(cis-2-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  1.10nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469351BDBM469351(cis-5-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  1.30nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469449BDBM469449(cis-2-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  1.30nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469364BDBM469364(cis-5-[8-Dimethylamino-1-[(1-hydroxy-cyclobutyl)-m...)
Affinity DataKi:  1.40nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469392BDBM469392(cis-5-[8-Dimethylamino-1-](1-methyl-cyclobutyl)-me...)
Affinity DataKi:  1.40nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469433BDBM469433(cis-5-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  1.60nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469439BDBM469439(cis-4-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  1.60nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469438BDBM469438(cis-1-(Cyclobutyl-methyl)-8-dimethylamino-3-(5-flu...)
Affinity DataKi:  1.60nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469444BDBM469444(cis-1-(Cyclobutyl-methyl)-8-dimethylamino-8-phenyl...)
Affinity DataKi:  1.60nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469374BDBM469374(cis-4-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  1.80nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469383BDBM469383(cis-4-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  1.80nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469443BDBM469443(cis-1-(Cyclobutyl-methyl)-8-dimethylamino-3-[2-met...)
Affinity DataKi:  1.80nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469370BDBM469370(cis-4-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  2nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469673BDBM469673(US10807988, Example SC_3308 | cis-8-Dimethylamino-...)
Affinity DataKi:  2nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469729BDBM469729(US10807988, Example SC_3365 | cis-8-Dimethylamino-...)
Affinity DataKi:  2nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469456BDBM469456(cis-8-Dimethylamino-1-[(1-hydroxy-cyclobutyl)-meth...)
Affinity DataKi:  2nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469469BDBM469469(cis-1-(Cyclopropyl-methyl)-8-dimethylamino-3-(2-fl...)
Affinity DataKi:  2nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469752BDBM469752(US10807988, Example SC_3389 | cis-3-[6-(Azetidin-1...)
Affinity DataKi:  2nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469695BDBM469695(US10807988, Example SC_3331 | cis-8-Dimethylamino-...)
Affinity DataKi:  2nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469465BDBM469465(cis-1-(Cyclopropyl-methyl)-8-dimethylamino-3-(4-me...)
Affinity DataKi:  2nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469718BDBM469718(US10807988, Example SC_3354 | cis-4-[5-(8-Dimethyl...)
Affinity DataKi:  2nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469750BDBM469750(US10807988, Example SC_3387 | cis-8-Dimethylamino-...)
Affinity DataKi:  2nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469460BDBM469460(cis-1-[(1-Hydroxy-cyclobutyl)-methyl]-8-methylamin...)
Affinity DataKi:  2nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469577BDBM469577(cis-3-(1,3-Benzodioxol-4-yl)-8-dimethylamino-8-phe...)
Affinity DataKi:  2nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrüNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 469422BDBM469422(cis-4-[1-(Cyclobutyl-methyl)-8-methylamino-2-oxo-8...)
Affinity DataKi:  2.20nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

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