Compile Data Set for Download or QSAR
Report error Found 302 Enz. Inhib. hit(s) with all data for entry = 9673
LigandChemical structure of BindingDB Monomer ID 474194BDBM474194(US10912773, Example 74 | 3-(6-chloro-2,3-dihydro-1...)
Affinity DataIC50: 2nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 480842BDBM480842(US10905688, Example 55, isomer 3 | 7-(4-methoxyben...)
Affinity DataIC50: 3nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474194BDBM474194(US10912773, Example 74 | 3-(6-chloro-2,3-dihydro-1...)
Affinity DataIC50: 3nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474162BDBM474162(US10912773, Example 44 | 6-ethyl-7-(4-methoxybenzy...)
Affinity DataIC50: 5nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474184BDBM474184(US10912773, Example 65 | 7-(cycloheptylmethyl)-6-m...)
Affinity DataIC50: 5nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474194BDBM474194(US10912773, Example 74 | 3-(6-chloro-2,3-dihydro-1...)
Affinity DataIC50: 5nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474110BDBM474110(US10912773, Example 3 | 6-Benzyl-7-(cyclohexylmeth...)
Affinity DataIC50: 6nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474184BDBM474184(US10912773, Example 65 | 7-(cycloheptylmethyl)-6-m...)
Affinity DataIC50: 6nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474150BDBM474150(US10912773, Example 36-isomer-2 | 7-(3-fluorobenzy...)
Affinity DataIC50: 7nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474197BDBM474197(US10912773, Example 77 | 3-isopropyl-7-(4-methoxyb...)
Affinity DataIC50: 7nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474143BDBM474143(US10912773, Example 33 | 7-(3-fluorobenzyl)-6-meth...)
Affinity DataIC50: 7nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474111BDBM474111(US10912773, Example 4 | 7-(Cyclohexylmethyl)-6-met...)
Affinity DataIC50: 7nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474110BDBM474110(US10912773, Example 3 | 6-Benzyl-7-(cyclohexylmeth...)
Affinity DataIC50: 8nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 480842BDBM480842(US10905688, Example 55, isomer 3 | 7-(4-methoxyben...)
Affinity DataIC50: 8nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474189BDBM474189(US10912773, Example 69 | 7-(4-methoxybenzyl)-6-met...)
Affinity DataIC50: 8nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474125BDBM474125(US10912773, Example 18 | 7-(3-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 8nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474147BDBM474147(US10905688, Example 35, isomer 3 | 7-(3-fluorobenz...)
Affinity DataIC50: 8nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474132BDBM474132(US10912773, Example 25 | 6-Methyl-7-(3-methylbenzy...)
Affinity DataIC50: 9nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474161BDBM474161(US10912773, Example 43 | 7-benzyl-6-ethyl-3-(tetra...)
Affinity DataIC50: 9nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474124BDBM474124(US10912773, Example 17 | 7-(2-Fluorobenzyl)-6-meth...)
Affinity DataIC50: 9nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474126BDBM474126(US10912773, Example 19 | 7-(2-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474184BDBM474184(US10912773, Example 65 | 7-(cycloheptylmethyl)-6-m...)
Affinity DataIC50: 10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474172BDBM474172(US10912773, Example 55-isomer-1 | 7-(4-methoxybenz...)
Affinity DataIC50: 10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474109BDBM474109(US10912773, Example 2 | 6-Benzyl-7-(3-fluorobenzyl...)
Affinity DataIC50: 11nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474212BDBM474212(US10912773, Example 92 | 6-(cyclopentylmethyl)-7-(...)
Affinity DataIC50: 11nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474111BDBM474111(US10912773, Example 4 | 7-(Cyclohexylmethyl)-6-met...)
Affinity DataIC50: 11nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474171BDBM474171(US10912773, Example 54 | 6-ethyl-7-(3-fluorobenzyl...)
Affinity DataIC50: 12nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474192BDBM474192(US10912773, Example 72 | (R)-7-(4-methoxybenzyl)-6...)
Affinity DataIC50: 12nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474110BDBM474110(US10912773, Example 3 | 6-Benzyl-7-(cyclohexylmeth...)
Affinity DataIC50: 12nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474123BDBM474123(US10912773, Example 16 | 7-Benzyl-6-methyl-3-(tetr...)
Affinity DataIC50: 12nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474130BDBM474130(US10912773, Example 23 | 7-(4-Methoxybenzyl)-6-met...)
Affinity DataIC50: 12nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474197BDBM474197(US10912773, Example 77 | 3-isopropyl-7-(4-methoxyb...)
Affinity DataIC50: 13nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 480842BDBM480842(US10905688, Example 55, isomer 3 | 7-(4-methoxyben...)
Affinity DataIC50: 13nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474189BDBM474189(US10912773, Example 69 | 7-(4-methoxybenzyl)-6-met...)
Affinity DataIC50: 13nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474109BDBM474109(US10912773, Example 2 | 6-Benzyl-7-(3-fluorobenzyl...)
Affinity DataIC50: 14nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474112BDBM474112(US10912773, Example 5 | 7-(3-Fluorobenzyl)-6-methy...)
Affinity DataIC50: 14nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474130BDBM474130(US10912773, Example 23 | 7-(4-Methoxybenzyl)-6-met...)
Affinity DataIC50: 14nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474122BDBM474122(US10912773, Example 15 | 6-Bromo-7-(3-fluorobenzyl...)
Affinity DataIC50: 15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474149BDBM474149(US10912773, Example 36-isomer-1 | 7-(3-fluorobenzy...)
Affinity DataIC50: 15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474121BDBM474121(US10912773, Example 14 | 7-(4-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474199BDBM474199(US10905688, Example 79 | 6-methyl-3-(tetrahydro-2H...)
Affinity DataIC50: 15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474210BDBM474210(US10912773, Example 90 | 7-(4-methoxybenzyl)-6-met...)
Affinity DataIC50: 15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474162BDBM474162(US10912773, Example 44 | 6-ethyl-7-(4-methoxybenzy...)
Affinity DataIC50: 16nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474167BDBM474167(US10912773, Example 50 | 7-(benzo[d][1,3]dioxol-5-...)
Affinity DataIC50: 16nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474119BDBM474119(US10912773, Example 12 | 7-(Cycloheptylmethyl)-3- ...)
Affinity DataIC50: 16nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474182BDBM474182(US10912773, Example 63 | 7-(cyclopentylmethyl)-6-m...)
Affinity DataIC50: 17nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474190BDBM474190(US10912773, Example 70 | 7-(4-methoxybenzyl)-6-met...)
Affinity DataIC50: 17nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474131BDBM474131(US10912773, Example 24 | 7-(4-Fluorobenzyl)-6-meth...)
Affinity DataIC50: 17nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474172BDBM474172(US10912773, Example 55-isomer-1 | 7-(4-methoxybenz...)
Affinity DataIC50: 17nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 474121BDBM474121(US10912773, Example 14 | 7-(4-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 18nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

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