Compile Data Set for Download or QSAR
maximum 50k data
Found 90 Enz. Inhib. hit(s) with all data for entry = 10700
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560649(1-(3-chloro-2-fluorobenzyl)- 4-((3-fluoro-4-methyl...)
Affinity DataIC50:  0.220nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560627((2R,4R)-1-(3-chloro-2,6- difluorobenzyl)-4-((3- fl...)
Affinity DataIC50:  0.330nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560660(US11384066, Example 78)
Affinity DataIC50:  0.370nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560652(1-(2,3-dichlorobenzyl)-4-((3- fluoro-4-methyl-6-((...)
Affinity DataIC50:  0.430nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560648((2R,4R)-1-(3-chloro-2,6-di- fluorobenzyl)-4-((3-fl...)
Affinity DataIC50:  0.520nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560664(US11384066, Example 90)
Affinity DataIC50:  0.540nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560632((2R,4R)-1-(2,3- difluorobenzyl)-4-((3- fluoro-6-((...)
Affinity DataIC50:  0.550nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560651((2R,4R)-1-(2,3-dichloro- benzyl)-4-((3-fluoro-4- m...)
Affinity DataIC50:  0.550nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560654(1-(3-chloro-2-fluorobenzyl)- 4-((4-ethyl-3-fluoro-...)
Affinity DataIC50:  0.570nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560644(US11384066, Example 39)
Affinity DataIC50:  0.570nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560626(US11384066, Example 5)
Affinity DataIC50:  0.590nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560661(1-(3-chloro-2-fluorobenzyl)- 4-((5-fluoro-4-methyl...)
Affinity DataIC50:  0.610nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560657(US11384066, Example 72)
Affinity DataIC50:  0.640nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560630((2R,4R)-1-(3-chloro-2- fluorobenzyl)-4-((3- chlor...)
Affinity DataIC50:  0.640nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560659((2R,4R)-1-(3-chloro-2-fluoro benzyl)-4-((4-chloro-...)
Affinity DataIC50:  0.670nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560647(US11384066, Example 49)
Affinity DataIC50:  0.700nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560666(1-(3-chloro-2-fluorobenzyl)- 4-((3,5-difluoro-6-((...)
Affinity DataIC50:  0.740nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560658((2R,4R)-1-(3-chloro-2-fluoro benzyl)-4-((4-chloro-...)
Affinity DataIC50:  0.760nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560662((2R,4R)-1-(3-chloro-2-fluorobenzyl)-4-((3-fluoro-6...)
Affinity DataIC50:  0.770nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560638((2R,4R)-1-(3-chloro-2,4- difluorobenzyl)-4-((3- fl...)
Affinity DataIC50:  0.810nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560643((2R,4R)-1-(2-(3-chloro-2- fluorophenyl)acetyl)-4-(...)
Affinity DataIC50:  0.850nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560646(US11384066, Example 45)
Affinity DataIC50:  0.880nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560653(1-(3-chloro-2,6-difluoro- benzyl)-4-((3-fluoro-4- ...)
Affinity DataIC50:  0.880nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560636((2R,4R)-1-(3,5-dichloro- 4-fluorobenzyl)-4-((3- fl...)
Affinity DataIC50:  0.910nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560656(4-((4-acetyl-3-fluoro-6-((5- methyl-1H-pyrazol-3-y...)
Affinity DataIC50:  0.910nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560667(US11384066, Example 102)
Affinity DataIC50:  0.930nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560668(US11384066, Example LY3295668)
Affinity DataIC50:  1nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560629((2R,4R)-1-(3-chloro-2- fluorobenzyl)-2-methyl-4- ...)
Affinity DataIC50:  1nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560640((2R,4R)-1-(3-chloro-2- fluorobenzyl)-4-((4-fluoro-...)
Affinity DataIC50:  1.10nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560665(US11384066, Example 91)
Affinity DataIC50:  1.10nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560628((2R,4R)-1-(3-chloro-2- fluorobenzyl)-2-ethyl-4- ((...)
Affinity DataIC50:  1.20nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560624(US11384066, Example 1)
Affinity DataIC50:  1.30nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560650(1-(2,3-difluorobenzyl)-4-((3- fluoro-4-methyl-6-((...)
Affinity DataIC50:  1.30nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560639((2R,4R)-1-(3-chloro-2- fluorobenzyl)-2-methyl-4- ...)
Affinity DataIC50:  1.40nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560663(US11384066, Example 84)
Affinity DataIC50:  1.40nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560641((2R,4R)-1-(3-chloro-2- fluorobenzyl)-2-methyl-4- (...)
Affinity DataIC50:  1.5nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560655(US11384066, Example 67)
Affinity DataIC50:  1.60nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560633((2R,4R)-1-(2-fluoro-3- methylbenzyl)-4-((3- fluor...)
Affinity DataIC50:  1.70nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560642((2R,4R)-1-(3-chloro-2- fluorobenzyl)-4-((3-fluoro-...)
Affinity DataIC50:  1.90nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560631((2R,4R)-1-(2,6- difluorobenzyl)-4-((3- fluoro-6-((...)
Affinity DataIC50:  2.40nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560645(US11384066, Example 41)
Affinity DataIC50:  2.70nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560637((2R,4R)-1-(3-chloro-2- fluorobenzyl)-4-((5-fluoro-...)
Affinity DataIC50:  2.90nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560625(US11384066, Example 2)
Affinity DataIC50:  2.90nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560635((2R,4R)-4-((3-fluoro-6- ((5-methyl-1H-pyrazol-3- y...)
Affinity DataIC50:  3.10nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560634((2R,4R)-1-(2,6- dichlorobenzyl)-4- ((3-fluoro-6-((...)
Affinity DataIC50:  3.20nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560651((2R,4R)-1-(2,3-dichloro- benzyl)-4-((3-fluoro-4- m...)
Affinity DataIC50:  309nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560647(US11384066, Example 49)
Affinity DataIC50:  310nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560657(US11384066, Example 72)
Affinity DataIC50:  372nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560654(1-(3-chloro-2-fluorobenzyl)- 4-((4-ethyl-3-fluoro-...)
Affinity DataIC50:  408nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560648((2R,4R)-1-(3-chloro-2,6-di- fluorobenzyl)-4-((3-fl...)
Affinity DataIC50:  439nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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