Compile Data Set for Download or QSAR
maximum 50k data
Found 70 Enz. Inhib. hit(s) with all data for entry = 10806
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477990(6-(cyclopropyl(hydroxy)methyl)-4-(4-methoxy-4-meth...)
Affinity DataIC50:  3nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477987(US10889591, Compound 108 | US11434248, Compound 10...)
Affinity DataIC50:  4nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477954(6-(3-hydroxyazetidin-1-yl)-2-oxo-4-(7-azaspiro[3.5...)
Affinity DataIC50:  5nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM570495(US11434248, Compound 160)
Affinity DataIC50:  5nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM478017(US10889591, Compound 154 | US11434248, Compound 15...)
Affinity DataIC50:  8nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477974(3-cyano-2-oxo-4-(6-azaspiro[2.5]octane-6-yl)-1,2-d...)
Affinity DataIC50:  8nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477944(US10889591, Compound 30 | US11434248, Compound 30)
Affinity DataIC50:  8nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477976(US10889591, Compound 85 | US11434248, Compound 85)
Affinity DataIC50:  8nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477962(6-methyl-2-oxo-4-(6-azaspiro[2.5]octane-6-yl)-1,2-...)
Affinity DataIC50:  9nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477952(6-(azetidin-1-yl)-2-oxo-4-(6-azaspiro[2.5]octane-6...)
Affinity DataIC50:  9nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM478019(4-(4-methoxy-4-methylpiperidin-1-yl)-6-methyl-2-ox...)
Affinity DataIC50:  9nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477942(4-(4-ethylphenyl)-2-oxo-1,2-dihydro-1,7-naphthyrid...)
Affinity DataIC50:  10nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477946(US10889591, Compound 33 | US11434248, Compound 33)
Affinity DataIC50:  10nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477991(US10889591, Compound 131 | US11434248, Compound 13...)
Affinity DataIC50:  11nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477984(3-cyano-N-methyl-2-oxo-4-(6-azaspiro[2.5]octane-6-...)
Affinity DataIC50:  11nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477989(US10889591, Compound 129 | US11434248, Compound 12...)
Affinity DataIC50:  11nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477951(6-isopropyl-2-oxo-4-(7-azaspiro[3.5]nonane-7-yl)-1...)
Affinity DataIC50:  12nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477943(US10889591, Compound 27 | US11434248, Compound 27)
Affinity DataIC50:  12nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477969(US10889591, Compound 79 | US11434248, Compound 79)
Affinity DataIC50:  12nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477982(6-(1-hydroxyethyl)-2-oxo-4-(7-azaspiro[3.5]nonane-...)
Affinity DataIC50:  12nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477964(6-methyl-2-oxo-4-(7-azaspiro[3.5]nonane-7-yl)-1,2-...)
Affinity DataIC50:  13nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477939(US10889591, Compound 23 | US11434248, Compound 23)
Affinity DataIC50:  13nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477977(US10889591, Compound 87 | US11434248, Compound 87)
Affinity DataIC50:  13nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477963(6-methoxy-2-oxo-4-(6-azaspiro[2.5]octane-6-yl)-1,2...)
Affinity DataIC50:  14nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477940(US10889591, Compound 24 | US11434248, Compound 24)
Affinity DataIC50:  14nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM478003(US10889591, Compound 138 | US11434248, Compound 13...)
Affinity DataIC50:  14nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477986(US10889591, Compound 107 | US11434248, Compound 10...)
Affinity DataIC50:  15nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477956(US10889591, Compound 53 | US11434248, Compound 53)
Affinity DataIC50:  15nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477966(6-ethyl-2-oxo-4-(6-azaspiro[2.5]octane-6-yl)-1,2-d...)
Affinity DataIC50:  16nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477978(6-(cyclopropyl (hydroxy)methyl)-2-oxo-4-(6-azaspir...)
Affinity DataIC50:  17nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477950(6-dimethylamino-2-oxo-4-(6-azaspiro[2.5]octane-6-y...)
Affinity DataIC50:  18nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477961(6-(hydroxymethyl)-2-oxo-4-(6-azaspiro[2.5]octane-6...)
Affinity DataIC50:  19nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477953(6-(3-hydroxyazetidin-1-yl)-2-oxo-4-(6-azaspiro[2.5...)
Affinity DataIC50:  19nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM478020(3-cyano-4-(4-methoxy-4-methylpiperidin-1-yl)-N,N-d...)
Affinity DataIC50:  20nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477970(US10889591, Compound 80 | US11434248, Compound 80)
Affinity DataIC50:  20nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM478002(US10889591, Compound 134 | US11434248, Compound 13...)
Affinity DataIC50:  21nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477965(US10889591, Compound 66 | US11434248, Compound 66)
Affinity DataIC50:  21nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477945(6-(1,2-dihydroxyethyl)-2-oxo-4-(6-azaspiro[2.5]oct...)
Affinity DataIC50:  22nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM478018(US10889591, Compound 156 | US11434248, Compound 15...)
Affinity DataIC50:  22nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477957(6-(azetidin-1-yl)-2-oxo-4-(7-azaspiro[3.5]nonane-7...)
Affinity DataIC50:  22nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477992(4-(4-methoxy-4-methylpiperidin-1-yl)-2-oxo-6-vinyl...)
Affinity DataIC50:  24nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477947((R)-4-(3-(1H-pyrazol-1-yl)pyrrolidin-1-yl)-6-morph...)
Affinity DataIC50:  25nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM478012(3-cyano-N-(2,3-dihydroxypropyl)-4-(4-methoxy-4-met...)
Affinity DataIC50:  25nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477985(3-cyano-N-(2-hydroxyethyl)-2-oxo-4-(6-aza-spiro[2....)
Affinity DataIC50:  27nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477938(US10889591, Compound 19 | US11434248, Compound 19)
Affinity DataIC50:  28nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477941(2-oxo-4-(6-azaspiro[2.5]octane-6-yl)-1,2-dihydro-1...)
Affinity DataIC50:  29nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477973(US10889591, Compound 82 | US11434248, Compound 82)
Affinity DataIC50:  29nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM478013(US10889591, Compound 145 | US11434248, Compound 14...)
Affinity DataIC50:  31nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM570444(US11434248, Compound 78)
Affinity DataIC50:  33nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477967(US10889591, Compound 77 | US11434248, Compound 77)
Affinity DataIC50:  33nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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