Compile Data Set for Download or QSAR
Report error Found 154 Enz. Inhib. hit(s) with all data for entry = 8031
LigandPNGBDBM230228(US9340500, I-072)
Affinity DataKi:  21nM ΔG°:  -45.6kJ/mole IC50: 45nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
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Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230164(US9340500, I-008)
Affinity DataIC50: 82nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
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Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230231(US9340500, I-075)
Affinity DataKi:  130nM ΔG°:  -40.9kJ/mole IC50: 270nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230172(US9340500, I-016)
Affinity DataIC50: 130nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230252(US9340500, I-096)
Affinity DataKi:  130nM ΔG°:  -40.9kJ/mole IC50: 420nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230253(US9340500, I-097)
Affinity DataKi:  130nM ΔG°:  -40.9kJ/mole IC50: 430nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230229(US9340500, I-073)
Affinity DataKi:  160nM ΔG°:  -40.3kJ/mole IC50: 340nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230187(US9340500, I-031)
Affinity DataKi:  160nM ΔG°:  -40.3kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230174(US9340500, I-018)
Affinity DataKi:  169nM ΔG°:  -40.2kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230264(US9340500, I-108)
Affinity DataKi:  170nM ΔG°:  -40.2kJ/mole IC50: 540nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230172(US9340500, I-016)
Affinity DataKi:  191nM ΔG°:  -39.9kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230227(US9340500, I-071)
Affinity DataKi:  196nM ΔG°:  -39.8kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230158(US9340500, I-002)
Affinity DataKi:  197nM ΔG°:  -39.8kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230278(US9340500, I-122)
Affinity DataKi:  240nM ΔG°:  -39.3kJ/mole IC50: 780nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230205(US9340500, I-049)
Affinity DataIC50: 240nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230219(US9340500, I-063)
Affinity DataKi:  251nM ΔG°:  -39.2kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230280(US9340500, I-124)
Affinity DataIC50: 260nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230227(US9340500, I-071)
Affinity DataIC50: 260nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230195(US9340500, I-039)
Affinity DataKi:  282nM ΔG°:  -38.9kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230256(US9340500, I-100)
Affinity DataKi:  290nM ΔG°:  -38.8kJ/mole IC50: 830nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230243(US9340500, I-087)
Affinity DataKi:  320nM ΔG°:  -38.6kJ/mole IC50: 710nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230203(US9340500, I-047)
Affinity DataKi:  320nM ΔG°:  -38.6kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230164(US9340500, I-008)
Affinity DataKi:  327nM ΔG°:  -38.5kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230174(US9340500, I-018)
Affinity DataIC50: 330nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230180(US9340500, I-024)
Affinity DataIC50: 340nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230194(US9340500, I-038)
Affinity DataKi:  352nM ΔG°:  -38.3kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230170(US9340500, I-014)
Affinity DataKi:  355nM ΔG°:  -38.3kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230158(US9340500, I-002)
Affinity DataIC50: 360nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230177(US9340500, I-021)
Affinity DataKi:  379nM ΔG°:  -38.1kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230246(US9340500, I-090)
Affinity DataKi:  380nM ΔG°:  -38.1kJ/mole IC50: 1.10E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230251(US9340500, I-095)
Affinity DataKi:  380nM ΔG°:  -38.1kJ/mole IC50: 970nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230239(US9340500, I-083)
Affinity DataIC50: 400nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230205(US9340500, I-049)
Affinity DataKi:  418nM ΔG°:  -37.9kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230182(US9340500, I-026)
Affinity DataKi:  427nM ΔG°:  -37.8kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230239(US9340500, I-083)
Affinity DataKi:  443nM ΔG°:  -37.7kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230279(US9340500, I-123)
Affinity DataKi:  450nM ΔG°:  -37.7kJ/mole IC50: 1.40E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230277(US9340500, I-121)
Affinity DataKi:  450nM ΔG°:  -37.7kJ/mole IC50: 1.40E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230169(US9340500, I-013)
Affinity DataKi:  453nM ΔG°:  -37.7kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230215(US9340500, I-059)
Affinity DataKi:  472nM ΔG°:  -37.6kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230219(US9340500, I-063)
Affinity DataIC50: 510nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230185(US9340500, I-029)
Affinity DataKi:  519nM ΔG°:  -37.3kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230249(US9340500, I-093)
Affinity DataKi:  530nM ΔG°:  -37.3kJ/mole IC50: 1.40E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230212(US9340500, I-056)
Affinity DataKi:  560nM ΔG°:  -37.1kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230247(US9340500, I-091)
Affinity DataKi:  560nM ΔG°:  -37.1kJ/mole IC50: 1.50E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230226(US9340500, I-070)
Affinity DataIC50: 590nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230207(US9340500, I-051)
Affinity DataKi:  590nM ΔG°:  -37.0kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230241(US9340500, I-085)
Affinity DataKi:  590nM ΔG°:  -37.0kJ/mole IC50: 1.30E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230254(US9340500, I-098)
Affinity DataKi:  590nM ΔG°:  -37.0kJ/mole IC50: 1.90E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230179(US9340500, I-023)
Affinity DataKi:  605nM ΔG°:  -36.9kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

LigandPNGBDBM230177(US9340500, I-021)
Affinity DataIC50: 610nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

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