Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with all data for entry = 10517
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543469(US11279702, Compound A1)
Affinity DataEC50:  200nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543470(2-((6-chloro-5-(2'-hydroxy-[1,1'-biphenyl]-4- yl)-...)
Affinity DataEC50:  1.40nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543471((((6-chloro-5-(2'-hydroxy-[1,1'-biphenyl]-4- yl)-1...)
Affinity DataEC50:  0.970nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543472(US11279702, Compound 3 | ethyl hydrogen (((6-chlor...)
Affinity DataEC50:  2.38nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543477(2-((6-chloro-5-(2'-hydroxy-4'-(1H-1,2,4- triazol-1...)
Affinity DataEC50:  1.10nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543474(2-((6-chloro-5-(4'-(3,3-dimethylbutyl)-2'- hydroxy...)
Affinity DataEC50:  1.12E+3nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543475((S)-2-((6-chloro-5-(4-(3-hydroxypyrrolidin- 1-yl)p...)
Affinity DataEC50:  43nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543476(2-((5-(4'-(1H-1,2,4-triazol-1-yl)-[1,1'- biphenyl]...)
Affinity DataEC50:  20nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543473((((6-chloro-5-(2'-hydroxy-[1,1'-biphenyl]-4- yl)-1...)
Affinity DataEC50:  0.550nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent