Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 10842
TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474361BDBM474361(US10858366, Example 52 | (S)-6-benzhydryl-11-hydro...)
Affinity DataIC50: 8nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474354BDBM474354(US10858366, Example 24 | (S)-6-((S)-(3-fluoropheny...)
Affinity DataIC50: 9nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474346BDBM474346(US10858366, Example 7 | (S)-6-benzhydryl-3-bromo-1...)
Affinity DataIC50: 9nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474343BDBM474343(US10858366, Example 4 | (S)-6-Benzhydryl-11-hydrox...)
Affinity DataIC50: 10nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474357BDBM474357(US10858366, Example 39 | (S)-6-((R)-(2-bromo-4-flu...)
Affinity DataIC50: 10nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474367BDBM474367(US10858366, Example 30 | (S)-6-((S)-(3-bromophenyl...)
Affinity DataIC50: 10nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474355BDBM474355(US10858366, Example 33 | (S)-6-((S)-(4-chloropheny...)
Affinity DataIC50: 20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474358BDBM474358(US10858366, Example 40 | (S)-6-((S)-(4-fluoropheny...)
Affinity DataIC50: 20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474359BDBM474359(US10858366, Example 43 | 3-((S)-(4-fluorophenyl)((...)
Affinity DataIC50: 20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474344BDBM474344(US10858366, Example 5 | (S)-6-Benzhydryl-3-chloro-...)
Affinity DataIC50: 20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474350BDBM474350(US10858366, Example 18 | (S)-6-((S)-(4-fluoropheny...)
Affinity DataIC50: 20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474349BDBM474349(US10858366, Example 17 | (S)-6-((R)-(4-fluoropheny...)
Affinity DataIC50: 20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474356BDBM474356(US10858366, Example 38 | (S)-6-((S)-(4-fluoropheny...)
Affinity DataIC50: 40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474347BDBM474347(US10858366, Example 8 | (S)-6-benzhydryl-3-cyclopr...)
Affinity DataIC50: 40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474345BDBM474345(US10858366, Example 6 | 6-benzhydryl-11-hydroxy-5,...)
Affinity DataIC50: 40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474366BDBM474366(US10858366, Example 78 | 6-benzhydryl-5-ethyl-11-h...)
Affinity DataIC50: 40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474351BDBM474351(US10858366, Example 19 | (S)-6-((R)-(4-fluoropheny...)
Affinity DataIC50: 40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474364BDBM474364(US10858366, Example 57 | (S)-6-benzhydryl-3-(diflu...)
Affinity DataIC50: 40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474353BDBM474353(US10858366, Example 23 | (S)-6-(bis(3-fluorophenyl...)
Affinity DataIC50: 50nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474340BDBM474340(US10858366, Example 1 | 6-Benzhydryl-11-hydroxy-5H...)
Affinity DataIC50: 50nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474360BDBM474360(US10858366, Example 46 | 3-((R)-(3-fluorophenyl)((...)
Affinity DataIC50: 50nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474362BDBM474362(US10858366, Example 53 | (S)-6-benzhydryl-11-hydro...)
Affinity DataIC50: 60nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474341BDBM474341(US10858366, Example 2 | 6-(bis(3-fluorophenyl)meth...)
Affinity DataIC50: 70nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474369BDBM474369(US10858366, Example 54 | (S)-6-benzhydryl-11-hydro...)
Affinity DataIC50: 100nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474363BDBM474363(US10858366, Example 56 | (S)-6-benzhydryl-11-hydro...)
Affinity DataIC50: 100nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474348BDBM474348(US10858366, Example 14 | (S)-6-benzhydryl-11-hydro...)
Affinity DataIC50: 100nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474365BDBM474365(US10858366, Example 75 | 6-benzhydryl-11-hydroxy-5...)
Affinity DataIC50: 100nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474352BDBM474352(US10858366, Example 20 | (S)-6-((R)-(4-fluoropheny...)
Affinity DataIC50: 300nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 474342BDBM474342(US10858366, Example 3 | 6-benzhydryl-11-hydroxy-5,...)
Affinity DataIC50: 400nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent