BDBM50166066 CHEMBL362991::H-Tyr-Pro-Phe-Pro-NH2::MORPHICEPTIN::Tyr-Pro-Phe-Pro-NH2::[D-Pro4]morphiceptin
SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(N)=O
InChI Key InChIKey=LSQXZIUREIDSHZ-ZJZGAYNASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50166066
Affinity DataKi: 36nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Inhibition of DAMGO (Tyr-[D-Ala]-Gly-[NMe-Phe]-Gly-ol) binding to rat brain mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 135nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 135nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
TargetNeuropeptides B/W receptor type 1(Homo sapiens (Human))
Addiction Research Foundation
Curated by PDSP Ki Database
Addiction Research Foundation
Curated by PDSP Ki Database
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of North Carolina At Wilmington
Curated by ChEMBL
University Of North Carolina At Wilmington
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Binding affinity towards non-selective opiate receptorMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin 2 from delta opioid receptor in Wistar rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 56.6nMAssay Description:Displacement of [3H]DAMGO from Wistar rat mu opioid receptor by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of North Carolina At Wilmington
Curated by ChEMBL
University Of North Carolina At Wilmington
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibitory activity against non-selective opiate receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 552nMAssay Description:In vitro inhibitory activity against mu opioid receptor using guinea pig ileum (GPI) assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.69E+3nMAssay Description:In vitro inhibitory activity against delta opioid receptor using mouse vas deferens (MVD) assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of North Carolina At Wilmington
Curated by ChEMBL
University Of North Carolina At Wilmington
Curated by ChEMBL
Affinity DataEC50: 741nMAssay Description:Agonist activity at human recombinant MOR expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair