BDBM22165 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine::CHEMBL153260::CHEMBL281594::CHEMBL542933::CHEMBL543876::GBR 12909::GBR-12909::NCGC00015300::US9944618, Compound ID No. 175::Vanoxerine
SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1
InChI Key InChIKey=NAUWTFJOPJWYOT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 22165
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University
Curated by ChEMBL
Wayne State University
Curated by ChEMBL
Affinity DataKi: 10.6nMAssay Description:Inhibition of rat brain dopamine transporter as accumulation of [3H]-DAMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University
Curated by ChEMBL
Wayne State University
Curated by ChEMBL
Affinity DataKi: 91.1nMAssay Description:Inhibition of rat brain Serotonin transporter as accumulation of [3H]-5-HTMore data for this Ligand-Target Pair
Affinity DataKi: 102nMAssay Description:Inhibition of rat brain Norepinephrin transporter as accumulation of [3H]-NEMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University
Curated by ChEMBL
Wayne State University
Curated by ChEMBL
Affinity DataIC50: 10.6nMAssay Description:Inhibition of [3H]-WIN- 35,428 binding to rat brain dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University
Curated by ChEMBL
Wayne State University
Curated by ChEMBL
Affinity DataIC50: 101nMAssay Description:Inhibition of rat brain Serotonin transporter uptake as [3H]-5-HT accumulationMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University
Curated by ChEMBL
Wayne State University
Curated by ChEMBL
Affinity DataIC50: 14.2nMAssay Description:Inhibition of rat brain Dopamine transporter uptake as [3H]-DA accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:Inhibition of rat brain Norepinephrin transporter as accumulation of [3H]-NEMore data for this Ligand-Target Pair