BDBM22165 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine::CHEMBL153260::CHEMBL281594::CHEMBL542933::CHEMBL543876::GBR 12909::GBR-12909::NCGC00015300::US9944618, Compound ID No. 175::Vanoxerine

SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=NAUWTFJOPJWYOT-UHFFFAOYSA-N

Data  106 KI  92 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 22165   

TargetTransporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataKi:  496nMAssay Description:Displacement of [3H]nisoxetine from NET in Sprague-Dawley rat brain cortex membranes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataIC50:  10.6nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat brain homogenates after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataIC50:  132nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed