BDBM22165 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine::CHEMBL153260::CHEMBL281594::CHEMBL542933::CHEMBL543876::GBR 12909::GBR-12909::NCGC00015300::US9944618, Compound ID No. 175::Vanoxerine
SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1
InChI Key InChIKey=NAUWTFJOPJWYOT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 22165
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Binding affinity Sprague-Dawley rats using [3H]WIN-35428 ligandMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Binding affinity at Dopamine transporter by displacing [3H]WIN-35428 from rat caudate putamenMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Binding affinity against Serotonin transporter in male Sprague-Dawley rats using [3H]paroxetine ligandMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 105nMAssay Description:Binding affinity at Serotonin transporter using [3H]citalopram as radioligand from rat brainMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 116nMAssay Description:Binding affinity of Sigma opioid receptor type 2 in rat liver membranes using [3H]DTG ligandMore data for this Ligand-Target Pair
TargetTransporter(Rattus norvegicus)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 1.27E+3nMAssay Description:Binding affinity at norepinephrine transporter using [3H]nisoxetine as radioligand from rat brainMore data for this Ligand-Target Pair
TargetTransporter(Rattus norvegicus)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 1.27E+3nMAssay Description:The compound was tested for binding affinity nisoxatine ligandMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Dopamine uptake in male Sprague-Dawley rats using [3H]DA ligandMore data for this Ligand-Target Pair