BDBM7460 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one::2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one::2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;hydrate::CHEMBL50::Quercetin::Quercetin (10)::Quercetin (21)::Quercetin (Qur)::US11021454, Compound Quercetin::US9180183, Quercetin::med.21724, Compound 4
SMILES Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O
InChI Key InChIKey=REFJWTPEDVJJIY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 7460
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center
Curated by PubChem BioAssay
Southern Research Specialized Biocontainment Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: >5.00E+4nMAssay Description:Southern Research's Specialized Biocontainment Screening Center (SRSBSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Librarie...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Broad Institute
Curated by PubChem BioAssay
Broad Institute
Curated by PubChem BioAssay
Affinity DataEC50: 1.01E+4nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 33(Homo sapiens (Human))
Broad Institute
Curated by PubChem BioAssay
Broad Institute
Curated by PubChem BioAssay
Affinity DataEC50: 1.24E+4nMAssay Description:Keywords: STK33 Kinase, Non-ATP Competitive Inhibitor Assay Overview: Purified STK33 Kinase is preincubated with potential inhibitors and allowed to ...More data for this Ligand-Target Pair
TargetOxytocin receptor(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: >2.99E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
Affinity DataEC50: 6.34E+4nMAssay Description:Inhibition of rat fetal brain CDK5 assessed as phosphorylated histone H1 levels by immuno-precipitationMore data for this Ligand-Target Pair
Affinity DataEC50: 3.50E+4nMAssay Description:Inhibition of SYK in human mast cells assessed as reduction in mast cell degranulationMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
WestfÄLische Wilhelms-UniversitÄ
Curated by PDSP Ki Database
WestfÄLische Wilhelms-UniversitÄ
Curated by PDSP Ki Database
Affinity DataEC50: >1.00E+5nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 8.02E+3nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.93E+3nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactmas...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Tahitian Noni International
Curated by ChEMBL
Tahitian Noni International
Curated by ChEMBL
Affinity DataEC50: >3.30E+5nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn
Curated by ChEMBL
University Of Bonn
Curated by ChEMBL
Affinity DataEC50: 278nMAssay Description:Activation of ABCG2 (unknown origin) ATPase activity expressed in baculovirus infected high five cell membranes by ascorbic acid/ammonia molybdate re...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn
Curated by ChEMBL
University Of Bonn
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Activation of recombinant human ABCG2 ATPase activity expressed in baculovirus infected High five insect cell membranes after 20 mins by ascorbic aci...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn
Curated by ChEMBL
University Of Bonn
Curated by ChEMBL
Affinity DataEC50: 278nMAssay Description:Activation of ABCG2 ATPase activity (unknown origin) expressed in baculovirus infected high5 cell membranes after 20 mins by ascorbic acid ammonia mo...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+3nMAssay Description:Inhibition of human CYP1B1 expressed in MDA-MB-468 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin EC50 at 6....More data for this Ligand-Target Pair
Affinity DataEC50: 8.80E+3nMAssay Description:Inhibition of human CYP1A1 transfected in HEK293 cells assessed as protection against CYP1A1 mediated B[a]P toxicity by measuring B[a]P EC50 at 20 uM...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Konkuk University
Curated by ChEMBL
Konkuk University
Curated by ChEMBL
Affinity DataEC50: 8.34E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataEC50: 8.34E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataEC50: 9.90E+5nMAssay Description:Antagonist activity at histamine H3 receptor in electrically-stimulated guinea pig ileumMore data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 4 hits for monomerid = 7460
ITC DataΔG°: -9.78kcal/mole −TΔS°: -0.257kcal/mole ΔH°: -9.58kcal/mole logk: 3.93E+7
pH: 7.5 T: 10.00°C
pH: 7.5 T: 10.00°C
ITC DataΔG°: -8.08kcal/mole −TΔS°: 0.840kcal/mole ΔH°: -8.92kcal/mole logk: 6.82E+5
pH: 7.0 T: 30.00°C
pH: 7.0 T: 30.00°C
ITC DataΔG°: -7.40kcal/mole −TΔS°: -2.66kcal/mole ΔH°: -4.74kcal/mole logk: 2.20E+5
pH: 7.0 T: 30.00°C
pH: 7.0 T: 30.00°C
ITC DataΔG°: -7.94kcal/mole −TΔS°: -2.82kcal/mole ΔH°: -5.12kcal/mole logk: 5.42E+5
pH: 7.0 T: 30.00°C
pH: 7.0 T: 30.00°C