Compile Data Set for Download or QSAR
Report error Found 89 Enz. Inhib. hit(s) with Target = '3-hydroxyacyl-[acyl-carrier-protein] dehydratase'
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50070942BDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135169BDBM50135169((2S,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153015BDBM50153015((-)epicatechingallate | (2R,3R)-2-(3,4-dihydroxyph...)
Affinity DataIC50: 400nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50070942BDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 400nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236531BDBM50236531((2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3...)
Affinity DataIC50: 600nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31965BDBM31965(carbohydrazide derivative, 5h)
Affinity DataIC50: 860nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31930BDBM31930(carbohydrazide derivative, 3m)
Affinity DataIC50: 1.42E+3nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7460BDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31927BDBM31927(carbohydrazide derivative, 3j)
Affinity DataIC50: 1.50E+3nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31934BDBM31934(carbohydrazide derivative, 3q)
Affinity DataIC50: 1.52E+3nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31926BDBM31926(carbohydrazide derivative, 3i)
Affinity DataIC50: 1.52E+3nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31964BDBM31964(carbohydrazide derivative, 5g)
Affinity DataIC50: 1.97E+3nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31928BDBM31928(carbohydrazide derivative, 3k)
Affinity DataIC50: 1.98E+3nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15236BDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7457BDBM7457(2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31960BDBM31960(carbohydrazide derivative, 5c)
Affinity DataIC50: 2.13E+3nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135169BDBM50135169((2S,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-...)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31967BDBM31967(carbohydrazide derivative, 5j)
Affinity DataIC50: 3.55E+3nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31963BDBM31963(carbohydrazide derivative, 5f)
Affinity DataIC50: 3.75E+3nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329257BDBM50329257(2-Hexadecynoic acid | CHEMBL1269411)
Affinity DataKi:  4.80E+3nMAssay Description:Competitive inhibition of Plasmodium falciparum FabZ using crotonyl-CoA as substrate by Michaelis-Menten steady state analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7459BDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [1-175](Yersinia pestis)
Brookhaven National Laboratory

LigandChemical structure of BindingDB Monomer ID 24777BDBM24777(5-hydroxy-1,4-dihydronaphthalene-1,4-dione | CHEMB...)
Affinity DataIC50: 5.30E+3nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Francisella tularensis)
Brookhaven National Laboratory

LigandChemical structure of BindingDB Monomer ID 24777BDBM24777(5-hydroxy-1,4-dihydronaphthalene-1,4-dione | CHEMB...)
Affinity DataIC50: 5.40E+3nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [1-175](Yersinia pestis)
Brookhaven National Laboratory

LigandChemical structure of BindingDB Monomer ID 50214969BDBM50214969(Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...)
Affinity DataIC50: 6.10E+3nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31925BDBM31925(carbohydrazide derivative, 3h)
Affinity DataIC50: 6.43E+3nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19459BDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Francisella tularensis)
Brookhaven National Laboratory

LigandChemical structure of BindingDB Monomer ID 50214969BDBM50214969(Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...)
Affinity DataIC50: 7.70E+3nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9461BDBM9461(5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26658BDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31966BDBM31966(carbohydrazide derivative, 5i)
Affinity DataIC50: 8.77E+3nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31931BDBM31931(carbohydrazide derivative, 3n)
Affinity DataIC50: 9.92E+3nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440622BDBM50440622(CHEMBL2426556)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7459BDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataKi:  1.15E+4nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31961BDBM31961(carbohydrazide derivative, 5d)
Affinity DataIC50: 1.28E+4nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [1-175](Yersinia pestis)
Brookhaven National Laboratory

LigandChemical structure of BindingDB Monomer ID 50056922BDBM50056922(cid_73677 | CHEMBL173530 | 1,4-Dihydroxy-10-methox...)
Affinity DataIC50: 1.30E+4nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440621BDBM50440621(CHEMBL2426554)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440620BDBM50440620(CHEMBL2426552)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26664BDBM26664(7-Hydroxy-flavone, 5a | 7-Hydroxyflavone, 11 | 7-h...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Francisella tularensis)
Brookhaven National Laboratory

LigandChemical structure of BindingDB Monomer ID 50056922BDBM50056922(cid_73677 | CHEMBL173530 | 1,4-Dihydroxy-10-methox...)
Affinity DataIC50: 2.78E+4nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440619BDBM50440619(CHEMBL2426555)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [1-175](Yersinia pestis)
Brookhaven National Laboratory

LigandChemical structure of BindingDB Monomer ID 11318BDBM11318(1,3,8-trihydroxy-6-methylanthra-9,10-quinone | CHE...)
Affinity DataIC50: 2.97E+4nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23420BDBM23420(CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50081950BDBM50081950(6-hydroxy-2-phenyl-4H-chromen-4-one | NSC-26744 | ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31917BDBM31917(carbohydrazide derivative, 1)
Affinity DataIC50: 3.98E+4nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187663BDBM50187663(5,7-dimethoxy-8-methyl-flavanone | CHEMBL207954)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandChemical structure of BindingDB Monomer ID 31959BDBM31959(carbohydrazide derivative, 5b)
Affinity DataIC50: 4.27E+4nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Francisella tularensis)
Brookhaven National Laboratory

LigandChemical structure of BindingDB Monomer ID 11318BDBM11318(1,3,8-trihydroxy-6-methylanthra-9,10-quinone | CHE...)
Affinity DataIC50: 4.31E+4nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440627BDBM50440627(CHEMBL2426553)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440624BDBM50440624(CHEMBL2426550)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(malaria parasite P. falciparum)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440623BDBM50440623(CHEMBL2426551)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Displayed 1 to 50 (of 89 total ) | Next | Last >>
Jump to: