Report error Found 328 with Last Name = 'lai' and Initial = 'ct'
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 49nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 97nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 100nM ΔG°: -40.0kJ/molepH: 8.0 T: 25°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
Affinity DataKi: 200nM ΔG°: -38.2kJ/molepH: 8.0 T: 25°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 286nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 350nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 460nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Affinity DataKi: 500nM ΔG°: -36.0kJ/molepH: 8.0 T: 25°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 792nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 900nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.63E+3nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 1.90E+3nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nM ΔG°: -31.5kJ/molepH: 8.0 T: 25°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
Affinity DataKi: 4.00E+3nM ΔG°: -30.8kJ/molepH: 8.0 T: 25°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 7.10E+3nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Affinity DataKi: 8.00E+3nM ΔG°: -29.1kJ/molepH: 8.0 T: 25°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 8.00E+3nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Affinity DataKi: 8.00E+3nM ΔG°: -29.1kJ/molepH: 8.0 T: 25°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 8.20E+3nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 1.21E+4nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 1.38E+4nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 1.60E+4nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+4nM ΔG°: -27.4kJ/molepH: 8.0 T: 25°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 2.19E+4nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 3.20E+4nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 4.69E+4nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 6.52E+4nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 6.90E+4nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 7.74E+4nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 9.28E+4nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 1.02E+5nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 1.05E+5nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 1.75E+5nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 3.05E+5nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: 3.57E+5nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Institute For Chemical Biology & Drug Discovery
Institute For Chemical Biology & Drug Discovery
Affinity DataKi: >4.00E+5nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.980nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of GST-tagged human recombinant ALK2 (145 to 509 residues) expressed in baculovirus expression system using casein as substrate in presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of GST-tagged human recombinant ALK1 expressed in baculovirus expression system using casein as substrate in presence of [gamma-32P]ATP in...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human FGFR2 (400 to 821 residues) using biotin-EQEDEPEGDYFEWLE-amide as substrate preincubated for 5 to 10 mins followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant N-terminal His-Avi-tag human FGFR3 (447 to 761 residues) expressed in Sf9 infected baculovirus expression system using biot...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant N-terminal His-Avi-tag human FGFR3 (447 to 761 residues) expressed in Sf9 infected baculovirus expression system using biot...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair