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Found 116 with Last Name = 'suckow' and Initial = 'ma'
TargetCollagenase 3(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268316(CHEMBL4080186)
Affinity DataKi:  0.470nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268309(CHEMBL4088060)
Affinity DataKi:  0.590nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268309(CHEMBL4088060)
Affinity DataKi:  0.710nMAssay Description:Inhibition of human recombinant MMP-8 catalytic domain (99 to 269 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50265157((6S,7S)-N-hydroxy-5-methyl-6-(4-(5-(trifluoromethy...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of APMA activated recombinant human full length MMP2 expressed in mouse cells using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50265157((6S,7S)-N-hydroxy-5-methyl-6-(4-(5-(trifluoromethy...)
Affinity DataKi:  3nMAssay Description:Inhibition of recombinant human MMP8 catalytic domain (Phe99 to Gln269 residues) expressed in Escherichia coli using McaKPLGL-Dpa-AR-NH2 as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268317(CHEMBL4076356)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human recombinant MMP-8 catalytic domain (99 to 269 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50388914(CHEMBL2063274 | US10357546, p-OH SB-3CT)
Affinity DataKi:  6nMAssay Description:Inhibition of recombinant human MMP2 expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50388914(CHEMBL2063274 | US10357546, p-OH SB-3CT)
Affinity DataKi:  6nMAssay Description:Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50265157((6S,7S)-N-hydroxy-5-methyl-6-(4-(5-(trifluoromethy...)
Affinity DataKi:  10nMAssay Description:Inhibition of recombinant human MMP9 catalytic domain (Phe107 to Pro449 residues) expressed in Escherichia coli using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50459505(CHEMBL4215451)
Affinity DataKi:  19nMAssay Description:Slow binding inhibition of human recombinant MMP9 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268316(CHEMBL4080186)
Affinity DataKi:  19nMAssay Description:Inhibition of human recombinant MMP-8 catalytic domain (99 to 269 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354624(CHEMBL1834422 | US10357546, ND-322 | US9951035, ND...)
Affinity DataKi:  24nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268317(CHEMBL4076356)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  28nMAssay Description:Inhibition of recombinant human MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50265157((6S,7S)-N-hydroxy-5-methyl-6-(4-(5-(trifluoromethy...)
Affinity DataKi:  30nMAssay Description:Inhibition of recombinant human MMP12 catalytic domain using Mca-PLGL-DpaAR-NH2 as substrate by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268310(CHEMBL4069479)
Affinity DataKi:  36nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50459506(CHEMBL4214929)
Affinity DataKi:  37nMAssay Description:Slow binding inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50442356(CHEMBL2442885 | US10357546, ND-380 | US9951035, ND...)
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50459506(CHEMBL4214929)
Affinity DataKi:  53nMAssay Description:Slow binding inhibition of human recombinant MMP14 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50265157((6S,7S)-N-hydroxy-5-methyl-6-(4-(5-(trifluoromethy...)
Affinity DataKi:  61nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged ADAM17 (Arg215 to Asn671 residues) expressed in baculovirus infected Sf21 cells using Mca-PLAQ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354622(CHEMBL1834418)
Affinity DataKi:  62nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50265157((6S,7S)-N-hydroxy-5-methyl-6-(4-(5-(trifluoromethy...)
Affinity DataKi:  68nMAssay Description:Inhibition of recombinant human MMP14 catalytic domain (89 to 265 residues) expressed in Escherichia coli using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354628(CHEMBL1834419)
Affinity DataKi:  69nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50367253(CHEMBL4167357)
Affinity DataKi:  73nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged ADAM10 (Thr214 to Glu672 residues) expressed in baculovirus infected Sf21 cells using McaKPLG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50265157((6S,7S)-N-hydroxy-5-methyl-6-(4-(5-(trifluoromethy...)
Affinity DataKi:  75nMAssay Description:Inhibition of recombinant human MMP7 expressed in Escherichia coli using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as substrate by fluorescence spe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM389618(US10357546, ND-336 | US9951035, ND-336 (5))
Affinity DataKi:  85nMAssay Description:Slow binding inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50459505(CHEMBL4215451)
Affinity DataKi:  119nMAssay Description:Slow binding inhibition of human recombinant MMP14 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM389618(US10357546, ND-336 | US9951035, ND-336 (5))
Affinity DataKi:  120nMAssay Description:Slow binding inhibition of human recombinant MMP14 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50459505(CHEMBL4215451)
Affinity DataKi:  127nMAssay Description:Slow binding inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)
Affinity DataKi:  130nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)
Affinity DataKi:  130nMAssay Description:Inhibition of human recombinant MMP9 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM389618(US10357546, ND-336 | US9951035, ND-336 (5))
Affinity DataKi:  150nMAssay Description:Slow binding inhibition of human recombinant MMP9 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50442364(CHEMBL2442889)
Affinity DataKi:  160nMAssay Description:Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50388914(CHEMBL2063274 | US10357546, p-OH SB-3CT)
Affinity DataKi:  160nMAssay Description:Inhibition of recombinant human MMP9 expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50442356(CHEMBL2442885 | US10357546, ND-380 | US9951035, ND...)
Affinity DataKi:  180nMAssay Description:Inhibition of human recombinant MMP-9 catalytic domain using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268311(CHEMBL4104422)
Affinity DataKi:  190nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50459506(CHEMBL4214929)
Affinity DataKi:  190nMAssay Description:Slow binding inhibition of human recombinant MMP9 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354624(CHEMBL1834422 | US10357546, ND-322 | US9951035, ND...)
Affinity DataKi:  210nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50442363(CHEMBL2442890 | US10357546, ND-395)
Affinity DataKi:  230nMAssay Description:Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50442364(CHEMBL2442889)
Affinity DataKi:  230nMAssay Description:Inhibition of human recombinant MMP-9 catalytic domain using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50442357(CHEMBL2442881)
Affinity DataKi:  240nMAssay Description:Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354625(CHEMBL1834423)
Affinity DataKi:  260nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50367253(CHEMBL4167357)
Affinity DataKi:  270nMAssay Description:Inhibition of recombinant human MMP12 catalytic domain using Mca-PLGL-DpaAR-NH2 as substrate by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50442355(CHEMBL2442886 | US10357546, ND-394)
Affinity DataKi:  290nMAssay Description:Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50442362(CHEMBL2442891)
Affinity DataKi:  310nMAssay Description:Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50265157((6S,7S)-N-hydroxy-5-methyl-6-(4-(5-(trifluoromethy...)
Affinity DataKi:  348nMAssay Description:Inhibition of recombinant human MMP1 catalytic domain (Phe100 to Gln268 residues) expressed in Escherichia coli using McaKPLGL-Dpa-AR-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50442360(CHEMBL2442893)
Affinity DataKi:  390nMAssay Description:Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  400nMAssay Description:Inhibition of recombinant human MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354626(CHEMBL1834421)
Affinity DataKi:  420nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50005100(CHEMBL2442884)
Affinity DataKi:  420nMAssay Description:Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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