Report error Found 272 Enz. Inhib. hit(s) with Target = 'Hypoxanthine-guanine phosphoribosyltransferase'
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of human HGPRT using fixed concentration of guanine and variable concentrations of PRib-PP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of human HGPRT using PRib-PP as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based methodMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Inhibition of human HGPRT assessed as inhibitor constant for enzyme-inhibitor-substrate complex formation using [5'-14C]IMP as substrate by scintilla...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based methodMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of recombinant human HGPRT using fixed concentration of guanine and variable concentrations of PRib-PP as substrate by Hanes plot analysisMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 4.60nMAssay Description:Inhibition of human HGPRT assessed as inhibitor constant for enzyme-inhibitor-substrate complex formation using [5'-14C]IMP as substrate by scintilla...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Inhibition of human HGPRT using PRib-PP as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Inhibition of human HGPRT using PRib-PP as the substrate by spectrophotometric methodMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of human HGPRT using fixed concentration of guanine and variable concentrations of PRib-PP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of recombinant human HGPRT using fixed concentration of guanine and variable concentrations of PRib-PP as substrate by Hanes plot analysisMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of human HGPRT using PRib-PP as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of human HGPRT using PRib-PP as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of human N-terminal hexahistidine-tagged HGPRTMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of human HGPRT using fixed concentration of guanine and variable concentrations of PRib-PP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant N-terminal 6His-tagged HGPRT expressed in Escherichia coli BL21 (DE3) using fixed concentration ...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Inhibition of human HGPRT assessed as inhibitor constant for enzyme-inhibitor complex formation using [5'-14C]IMP as substrate by scintillation count...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant N-terminal 6His-tagged HGPRT expressed in Escherichia coli BL21 (DE3) using fixed concentration ...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant N-terminal 6His-tagged HGPRT expressed in Escherichia coli BL21 (DE3) using fixed concentration ...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 70nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 70nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by spectrophotometric assay in presence of guanineMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by spectrophotometric assay in presence of guanineMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Inhibition of human HGPRT using PRib-PP as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Inhibition of human HGPRT using PRib-PP as substrate by Hanes-plot based methodMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 100nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 100nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of recombinant human HGPRT expressed in Escherichia coli Sphi606 cells by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based methodMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by spectrophotometric assay in presence of guanineMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 100nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysisMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of human recombinant HGPRT expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of human HGPRT using PRib-PP as the substrate by spectrophotometric methodMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of human HGPRT using PRib-PP as the substrate by spectrophotometric methodMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by spectrophotometric assay in presence of guanineMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of human HGPRT using PRib-PP as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by spectrophotometric assay in presence of guanineMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of human HGPRT using PRib-PP as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant N-terminal 6His-tagged HGPRT expressed in Escherichia coli BL21 (DE3) using fixed concentration ...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by spectrophotometric assay in presence of guanineMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 150nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
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