Compile Data Set for Download or QSAR
maximum 50k data
Found 65 Enz. Inhib. hit(s) with all data for entry = 11497
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621042((6-((4-(2-(diethylamino)benzothiazole-6-yl)-5-fluo...)
Affinity DataIC50:  8nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621035((6-((4-(2-(dimethylamino)benzothiazole-6-yl)-5-flu...)
Affinity DataIC50:  9nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621015((6-((4-(2-(diethylamino)benzothiazole-6-yl)-5-fluo...)
Affinity DataIC50:  14nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621015((6-((4-(2-(diethylamino)benzothiazole-6-yl)-5-fluo...)
Affinity DataIC50:  14nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621018(N,N-diethyl-6-(2-((5-((4-ethylpiperazine-1-yl)meth...)
Affinity DataIC50:  15nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621042((6-((4-(2-(diethylamino)benzothiazole-6-yl)-5-fluo...)
Affinity DataIC50:  15nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621006((6-((4-(2-(dimethylamino)benzothiazole-6-yl)-5-flu...)
Affinity DataIC50:  16nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621035((6-((4-(2-(dimethylamino)benzothiazole-6-yl)-5-flu...)
Affinity DataIC50:  18nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621048(N,N-diethyl-6-(5-fluoro-2-((5-(piperazine-1 -yl)py...)
Affinity DataIC50:  23nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621046((6-((5-fluoro-4-(2-methylbenzothiazole-6-yl)pyrimi...)
Affinity DataIC50:  27nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621039(N,N-diethyl-6-5-fluoro-2-((5-((4-isopropylpiperazi...)
Affinity DataIC50:  31nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM620995((6-((4-(benzothiazole-6-yl)-5-fluoropyrimidine-2-y...)
Affinity DataIC50:  35nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621030((6-((4-(2-(diethylamino)benzothiazole-6-yl)-5-fluo...)
Affinity DataIC50:  39nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621030((6-((4-(2-(diethylamino)benzothiazole-6-yl)-5-fluo...)
Affinity DataIC50:  39nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621047((6-((4-(2-(dimethylamino)benzothiazole-6-yl)-5-flu...)
Affinity DataIC50:  41nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621024(N,N-diethyl-6-(5-fluoro-2-((5-(piperazine-1 -ylmet...)
Affinity DataIC50:  45nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621006((6-((4-(2-(dimethylamino)benzothiazole-6-yl)-5-flu...)
Affinity DataIC50:  57nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621041(6-(5-fluoro-2-((5-(piperazine-1-ylmethyl)pyridine-...)
Affinity DataIC50:  59nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621012(6-(5-fluoro-2-((5-(piperazine-1-yl)pyridine-2-yl)a...)
Affinity DataIC50:  61nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621029((6-((4-(2-(cyclopentylamino)benzothiazole-6-yl)-5-...)
Affinity DataIC50:  74nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621019(4-(benzothiazole-6-yl)-5-fluoro-N-(5-(piperazine-1...)
Affinity DataIC50:  85nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621043(US20230303553, Example 16 | tert-butyl 4-(6-((5-fl...)
Affinity DataIC50:  86nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621049((6-((4-(2-(cyclopentylamino)benzothiazole-6-yl)-5-...)
Affinity DataIC50:  90nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621046((6-((5-fluoro-4-(2-methylbenzothiazole-6-yl)pyrimi...)
Affinity DataIC50:  93nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM620998(N-cyclopentyl-6-(2-((5-((4-ethylpiperazine-1-yl)me...)
Affinity DataIC50:  96nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621013(6-((4-(benzothiazole-6-yl)-5-fluoropyrimidine-2-yl...)
Affinity DataIC50:  104nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621029((6-((4-(2-(cyclopentylamino)benzothiazole-6-yl)-5-...)
Affinity DataIC50:  106nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621010(US20230303553, Example 5 | tert-butyl 4-(6-((4-(be...)
Affinity DataIC50:  111nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621011((6-((4-(2-(cyclopentylamino)benzothiazole-6-yl)-5-...)
Affinity DataIC50:  116nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621031((4-ethylpiperazine-1-yl)(6-((5-fluoro-4-(2-methylb...)
Affinity DataIC50:  127nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621019(4-(benzothiazole-6-yl)-5-fluoro-N-(5-(piperazine-1...)
Affinity DataIC50:  129nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621026(N-cyclopentyl-6-(5-fluoro-2-((5-((4-isopropylpiper...)
Affinity DataIC50:  132nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621023(N-cyclopentyl-6-(5-fluoro-2-((5-(piperazine-1 -yl)...)
Affinity DataIC50:  139nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621050(6-(5-fluoro-2-((5-((4-isopropylpiperazine-1 -yl)me...)
Affinity DataIC50:  142nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM620995((6-((4-(benzothiazole-6-yl)-5-fluoropyrimidine-2-y...)
Affinity DataIC50:  144nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621025(US20230303553, Example 10 | ethyl 4-((6-((4-(benzo...)
Affinity DataIC50:  169nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621028(4-(benzothiazole-6-yl)-5-fluoro-N-(5-((4-isopropyl...)
Affinity DataIC50:  175nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621018(N,N-diethyl-6-(2-((5-((4-ethylpiperazine-1-yl)meth...)
Affinity DataIC50:  197nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621005(N-cyclopentyl-6-(5-fluoro-2-((5-(piperazine-1 -ylm...)
Affinity DataIC50:  201nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621034(N-(5-((4-ethylpiperazine-1-yl)methyl)pyridine-2-yl...)
Affinity DataIC50:  210nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621001(4-(benzothiazole-6-yl)-N-(5-((4-ethylpiperazine-1-...)
Affinity DataIC50:  244nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621032(6-(2-((5-((4-ethylpiperazine-1-yl)methyl)pyridine-...)
Affinity DataIC50:  254nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621028(4-(benzothiazole-6-yl)-5-fluoro-N-(5-((4-isopropyl...)
Affinity DataIC50:  263nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621007(4-(benzothiazole-6-yl)-5-fluoro-N-(5-(piperazine-1...)
Affinity DataIC50:  268nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621004(US20230303553, Example 3 | tert-butyl 4-((6-((4-(b...)
Affinity DataIC50:  272nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621024(N,N-diethyl-6-(5-fluoro-2-((5-(piperazine-1 -ylmet...)
Affinity DataIC50:  290nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621027(US20230303553, Example 46 | tert-butyl 4-(6-((4-(2...)
Affinity DataIC50:  443nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621040(5-fluoro-4-(2-methylbenzothiazole-6-yl)-N-(5-(pipe...)
Affinity DataIC50:  464nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621009(US20230303553, Example 40 | tert-butyl 4-(6-((4-(2...)
Affinity DataIC50: >1.00E+3nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621021(US20230303553, Example 44 | tert-butyl 4-((6-((4-(...)
Affinity DataIC50: >1.00E+3nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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