Found 65 Enz. Inhib. hit(s) with all data for entry = 11497 
Affinity DataIC50: 8nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Affinity DataIC50: 9nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 14nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Affinity DataIC50: 14nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Affinity DataIC50: 15nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Affinity DataIC50: 16nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Affinity DataIC50: 27nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Affinity DataIC50: 35nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Affinity DataIC50: 39nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Affinity DataIC50: 85nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 104nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Affinity DataIC50: 106nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Affinity DataIC50: 111nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 116nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 127nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 129nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 139nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 142nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 144nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 169nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 175nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Affinity DataIC50: 197nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Affinity DataIC50: 201nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 244nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 254nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Affinity DataIC50: 263nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Affinity DataIC50: 268nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 272nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Affinity DataIC50: 290nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Affinity DataIC50: 443nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: 464nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
