Compile Data Set for Download or QSAR
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Report error Found 130 Enz. Inhib. hit(s) with all data for entry = 50017937
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188749(1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)...)
Affinity DataIC50:  11nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188753(3-(3-chlorophenyl)-1-methyl-1-((5-(7-((4-methylpip...)
Affinity DataIC50:  12nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188731(1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)
Affinity DataIC50:  13nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188749(1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)...)
Affinity DataIC50:  14nMAssay Description:Inhibition of FLT1 at 1mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188764(3-(4-fluorophenyl)-1-methyl-1-((5-(7-((4-methylpip...)
Affinity DataIC50:  16nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188748(1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)
Affinity DataIC50:  17nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188754(3-(4-bromophenyl)-1-methyl-1-((5-(7-((4-methylpipe...)
Affinity DataIC50:  17nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188759(1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)...)
Affinity DataIC50:  17nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188769(3-(3,4-dichlorophenyl)-1-methyl-1-((5-(7-((4-methy...)
Affinity DataIC50:  18nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188749(1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)...)
Affinity DataIC50:  18nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188759(1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)...)
Affinity DataIC50:  19nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188727(1-methyl-1-((5-(6-((4-methylpiperazin-1-yl)methyl)...)
Affinity DataIC50:  19nMAssay Description:Inhibition of FLT1 at 1mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188754(3-(4-bromophenyl)-1-methyl-1-((5-(7-((4-methylpipe...)
Affinity DataIC50:  19nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188753(3-(3-chlorophenyl)-1-methyl-1-((5-(7-((4-methylpip...)
Affinity DataIC50:  20nMAssay Description:Inhibition of FLT1 at 1mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188736(3-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-1-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188732(1-cyclopropyl-1-((5-(6-((4-methylpiperazin-1-yl)me...)
Affinity DataIC50:  21nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188752(3-(4-chlorophenyl)-1-methyl-1-((5-(7-((4-methylpip...)
Affinity DataIC50:  21nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188761(1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)
Affinity DataIC50:  24nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188759(1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)...)
Affinity DataIC50:  25nMAssay Description:Inhibition of FLT1 at 1mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188736(3-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-1-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188727(1-methyl-1-((5-(6-((4-methylpiperazin-1-yl)methyl)...)
Affinity DataIC50:  27nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188737(1-(3,5-dimethylphenyl)-3-((5-(6-((4-methylpiperazi...)
Affinity DataIC50:  27nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188769(3-(3,4-dichlorophenyl)-1-methyl-1-((5-(7-((4-methy...)
Affinity DataIC50:  28nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188736(3-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-1-...)
Affinity DataIC50:  33nMAssay Description:Inhibition of FLT1 at 1mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188748(1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)
Affinity DataIC50:  34nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188733(1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)
Affinity DataIC50:  35nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188752(3-(4-chlorophenyl)-1-methyl-1-((5-(7-((4-methylpip...)
Affinity DataIC50:  36nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188769(3-(3,4-dichlorophenyl)-1-methyl-1-((5-(7-((4-methy...)
Affinity DataIC50:  36nMAssay Description:Inhibition of FLT1 at 1mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188754(3-(4-bromophenyl)-1-methyl-1-((5-(7-((4-methylpipe...)
Affinity DataIC50:  38nMAssay Description:Inhibition of FLT1 at 1mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188735(1-(3,5-dichlorophenyl)-3-((5-(6-((4-methylpiperazi...)
Affinity DataIC50:  38nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188732(1-cyclopropyl-1-((5-(6-((4-methylpiperazin-1-yl)me...)
Affinity DataIC50:  38nMAssay Description:Inhibition of FLT1 at 1mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188753(3-(3-chlorophenyl)-1-methyl-1-((5-(7-((4-methylpip...)
Affinity DataIC50:  38nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188751((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydro...)
Affinity DataIC50:  42nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210283(1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)...)
Affinity DataIC50:  44nMAssay Description:Inhibition of FLT1 at 1mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188756(1-ethyl-1-((5-(6-((4-methylpiperazin-1-yl)methyl)-...)
Affinity DataIC50:  45nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188757(1-((5-(7-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)
Affinity DataIC50:  48nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210283(1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)...)
Affinity DataIC50:  51nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188727(1-methyl-1-((5-(6-((4-methylpiperazin-1-yl)methyl)...)
Affinity DataIC50:  56nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188764(3-(4-fluorophenyl)-1-methyl-1-((5-(7-((4-methylpip...)
Affinity DataIC50:  59nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188733(1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)
Affinity DataIC50:  59nMAssay Description:Inhibition of FLT1 at 1mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188739(1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)
Affinity DataIC50:  61nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188737(1-(3,5-dimethylphenyl)-3-((5-(6-((4-methylpiperazi...)
Affinity DataIC50:  63nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188752(3-(4-chlorophenyl)-1-methyl-1-((5-(7-((4-methylpip...)
Affinity DataIC50:  64nMAssay Description:Inhibition of FLT1 at 1mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188757(1-((5-(7-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)
Affinity DataIC50:  69nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188733(1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)
Affinity DataIC50:  75nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188735(1-(3,5-dichlorophenyl)-3-((5-(6-((4-methylpiperazi...)
Affinity DataIC50:  79nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188764(3-(4-fluorophenyl)-1-methyl-1-((5-(7-((4-methylpip...)
Affinity DataIC50:  83nMAssay Description:Inhibition of FLT1 at 1mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188739(1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)
Affinity DataIC50:  86nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210283(1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)...)
Affinity DataIC50:  96nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188728(1-((5-(7-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)
Affinity DataIC50:  101nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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