Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50039189
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321043(1-(5-Chloro-2-trifluoromethyl-benzyl)-7-[6-(4-meth...)
Affinity DataIC50:  10nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321054(1-(5-Chloro-2-trifluoromethyl-benzyl)-7-(2-piperaz...)
Affinity DataIC50:  10nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321053(CHEMBL1163559 | {4-[1-(5-Chloro-2-trifluoromethyl-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321046(1-(2-Chloro-3,6-difluoro-benzyl)-7-[6-(4-methylpip...)
Affinity DataIC50:  11nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321045(1-(2,5-Dichloro-benzyl)-7-[6-(4-methyl-piperazin-1...)
Affinity DataIC50:  11nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321040(CHEMBL1165318 | {4-[1-(2,5-Difluoro-benzyl)-1,2,3,...)
Affinity DataIC50:  15nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321055(1-[4-(4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,...)
Affinity DataIC50:  17nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321038(CHEMBL1165334 | {4-[1-(2,6-Dichloro-benzyl)-1,2,3,...)
Affinity DataIC50:  27nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321042(1-(2,5-Difluoro-benzyl)-7-[6-(4-methyl-piperazin-1...)
Affinity DataIC50:  33nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321052(CHEMBL1163567 | {1-[(5-Chloro-2-trifluoromethyl)be...)
Affinity DataIC50:  40nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321058(CHEMBL1163518 | {1-[(5-Chloro-2-trifluoromethyl)be...)
Affinity DataIC50:  121nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321041((S)-1-(2,5-difluorobenzyl)-7-(4-(2-(pyrrolidin-1-y...)
Affinity DataIC50:  145nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321054(1-(5-Chloro-2-trifluoromethyl-benzyl)-7-(2-piperaz...)
Affinity DataIC50:  150nMAssay Description:Inhibition of ALK phosphorylation in human Karpas-299 cells by immunoblotting and ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321042(1-(2,5-Difluoro-benzyl)-7-[6-(4-methyl-piperazin-1...)
Affinity DataIC50:  200nMAssay Description:Inhibition of ALK phosphorylation in human Karpas-299 cells by immunoblotting and ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321055(1-[4-(4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,...)
Affinity DataIC50:  250nMAssay Description:Inhibition of ALK phosphorylation in human Karpas-299 cells by immunoblotting and ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321053(CHEMBL1163559 | {4-[1-(5-Chloro-2-trifluoromethyl-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of ALK phosphorylation in human Karpas-299 cells by immunoblotting and ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50378787(CHEMBL1202141)
Affinity DataIC50:  256nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321039((S)-1-(2,6-dichlorobenzyl)-7-(4-(2-(pyrrolidin-1-y...)
Affinity DataIC50:  278nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321052(CHEMBL1163567 | {1-[(5-Chloro-2-trifluoromethyl)be...)
Affinity DataIC50:  450nMAssay Description:Inhibition of ALK phosphorylation in human Karpas-299 cells by immunoblotting and ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321047(1-(2,5-Difluoro-benzenesulfonyl)-7-[6-(4-methylpip...)
Affinity DataIC50:  465nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321044(1-(2-Chloro-5-trifluoromethyl-benzyl)-7-[6-(4-meth...)
Affinity DataIC50:  506nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321057(4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321050(4-(2,5-Difluoro-benzyl)-6-[6-(4-methyl-piperazin-1...)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321051(1-(2,5-Dichloro-benzyl)-4-methyl-7-[6-(4-methyl-pi...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321056(4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321049(4-(2-Chloro-3,6-difluoro-phenoxy)-6-[6-(4-methylpi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321037((S)-1-benzyl-7-(4-(2-(pyrrolidin-1-ylmethyl)pyrrol...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321048((2,5-Difluoro-phenyl)-{7-[4-((S)-2-pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed