Affinity DataKi: 4.27E+3nMAssay Description:Competitive inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using 250 uM ATP and vary...More data for this Ligand-Target Pair
Affinity DataKi: 4.79E+3nMAssay Description:Uncompetitive inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using varying concentra...More data for this Ligand-Target Pair
Affinity DataKi: 9.59E+3nMAssay Description:Competitive inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using 250 uM ATP and vary...More data for this Ligand-Target Pair
Affinity DataKi: 1.03E+4nMAssay Description:Uncompetitive inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using varying concentra...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of RET (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of RET (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of RET (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of RET (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of RET (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of RET (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of RET (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
TargetEndoplasmic reticulum chaperone BiP(Homo sapiens (Human))
University of Arizona
Curated by ChEMBL
University of Arizona
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...More data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 870nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Inhibition of EphB2 (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Affinity DataIC50: 890nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
Affinity DataIC50: 930nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of KDR (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KDR (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed ...More data for this Ligand-Target Pair
Target60 kDa heat shock protein, mitochondrial(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Roset...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of KDR (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed a...More data for this Ligand-Target Pair
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