TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universidad De Talca
Curated by ChEMBL
Universidad De Talca
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Competitive inhibition of recombinant GST-tagged VEGFR2 cytoplasmic domain in presence of ATPMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 151nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 217nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 460nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 3.80E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 4.50E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 6.70E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 1.05E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 2.93E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 2.95E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 4.87E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 2.32E+5nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Antagonist activity at (alpha4beta2)2alpha5 nAChR (unknown origin) expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced curre...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonist activity at (alpha4beta2)2alpha4 nAChR (unknown origin) expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced curre...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 166nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Antagonist activity at (alpha4beta2)2beta2 nAChR (unknown origin) expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced curren...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 528nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
Affinity DataIC50: 540nMpH: 7.6 T: 2°CAssay Description:In a 96-well plate, 50 uL of the sample dissolved in phosphate buffer (8 mmol/L K2HPO4, 2.3 mmol/L NaH2PO4, 150 mmol/L NaCl, and 0.05% Tween 20 at pH...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 759nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 1.02E+3nMAssay Description:Antagonist activity at (alpha4beta2)2alpha4 nAChR (unknown origin) expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced curre...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 1.61E+3nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at (alpha4beta2)2beta2 nAChR (unknown origin) expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced curren...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Antagonist activity at (alpha4beta2)2beta2 nAChR (unknown origin) expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced curren...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Antagonist activity at (alpha4beta2)2alpha4 nAChR (unknown origin) expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced curre...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at (alpha4beta2)2beta2 nAChR (unknown origin) expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced curren...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Antagonist activity at (alpha4beta2)2alpha5 nAChR (unknown origin) expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced curre...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 7.60E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
Affinity DataIC50: 8.80E+3nMpH: 7.6 T: 2°CAssay Description:In a 96-well plate, 50 uL of the sample dissolved in phosphate buffer (8 mmol/L K2HPO4, 2.3 mmol/L NaH2PO4, 150 mmol/L NaCl, and 0.05% Tween 20 at pH...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 8.90E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 1.34E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 1.78E+4nMAssay Description:Antagonist activity at (alpha4beta2)2alpha5 nAChR (unknown origin) expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced curre...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 2.11E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
Affinity DataIC50: 2.56E+4nMpH: 7.6 T: 2°CAssay Description:In a 96-well plate, 50 uL of the sample dissolved in phosphate buffer (8 mmol/L K2HPO4, 2.3 mmol/L NaH2PO4, 150 mmol/L NaCl, and 0.05% Tween 20 at pH...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 2.58E+4nMAssay Description:Antagonist activity at (alpha4beta2)2beta2 nAChR (unknown origin) expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced curren...More data for this Ligand-Target Pair
Affinity DataIC50: 2.91E+4nMpH: 7.6 T: 2°CAssay Description:In a 96-well plate, 50 uL of the sample dissolved in phosphate buffer (8 mmol/L K2HPO4, 2.3 mmol/L NaH2PO4, 150 mmol/L NaCl, and 0.05% Tween 20 at pH...More data for this Ligand-Target Pair