Affinity DataIC50: 11nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of EGFR in human MCF7 cell lysates after 24 to 48 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of EGFR in human MCF7 cell lysates after 24 to 48 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of EGFR in human MCF7 cell lysates after 24 to 48 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of EGFR in human MCF7 cell lysates after 24 to 48 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of EGFR in human MCF7 cell lysates after 24 to 48 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of EGFR in human MCF7 cell lysates after 24 to 48 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of EGFR in human MCF7 cell lysates after 24 to 48 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of EGFR in human MCF7 cell lysates after 24 to 48 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of EGFR in human MCF7 cell lysates after 24 to 48 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of EGFR in human MCF7 cell lysates after 24 to 48 hrs by ELISAMore data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research
Curated by ChEMBL
National Organization For Drug Control & Research
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of CDK2/cyclin A expressed in baculovirus infected insect Sf21 cells using [gamma-P32]ATP and histone H1 as substrate after 10 mins by rad...More data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of EGFR in human MCF7 cell lysates after 24 to 48 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of EGFR in human MCF7 cell lysates after 24 to 48 hrs by ELISAMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universiti Putra Malaysia
Curated by ChEMBL
Universiti Putra Malaysia
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human 5-LOX in human peripheral blood mononuclear leukocytes assessed as inhibition of calymycin A23187-stimulated LTB4 production prei...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research
Curated by ChEMBL
National Organization For Drug Control & Research
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of CDK2/cyclin A expressed in baculovirus infected insect Sf21 cells using [gamma-P32]ATP and histone H1 as substrate after 10 mins by rad...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Universiti Putra Malaysia
Curated by ChEMBL
Universiti Putra Malaysia
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of 5-LOX in calcium ionophore A23187-stimulated NMRI mouse macrophage assessed as inhibition of LTC4 production preincubated for 60 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant COX2 expressed in insect Sf21 cells assessed as inhibition of conversion of arachidonic acid to PGE2 preincubated for...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universiti Putra Malaysia
Curated by ChEMBL
Universiti Putra Malaysia
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of human 5-LOX in human peripheral blood mononuclear leukocytes assessed as inhibition of calymycin A23187-stimulated LTB4 production prei...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research
Curated by ChEMBL
National Organization For Drug Control & Research
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK2/cyclin A expressed in baculovirus infected insect Sf21 cells using [gamma-P32]ATP and histone H1 as substrate after 10 mins by rad...More data for this Ligand-Target Pair
Affinity DataIC50: 752nMAssay Description:Inhibition of recombinant human C-terminal His/N-terminal GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus infected Sf9 cells using bi...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research
Curated by ChEMBL
National Organization For Drug Control & Research
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of CDK2/cyclin A expressed in baculovirus infected insect Sf21 cells using [gamma-P32]ATP and histone H1 as substrate after 10 mins by rad...More data for this Ligand-Target Pair
Affinity DataIC50: 901nMAssay Description:Inhibition of recombinant human C-terminal His/N-terminal GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus infected Sf9 cells using bi...More data for this Ligand-Target Pair
Affinity DataIC50: 951nMAssay Description:Inhibition of recombinant human C-terminal His/N-terminal GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus infected Sf9 cells using bi...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Egyptian Russian University
Curated by ChEMBL
Egyptian Russian University
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GST-tagged recombinant human CDK2/cyclin E expressed in insect SF-9 cells after 10 mins by scintillation counting analysis in presence ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Egyptian Russian University
Curated by ChEMBL
Egyptian Russian University
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GST-tagged recombinant human CDK2/cyclin E expressed in insect SF-9 cells after 10 mins by scintillation counting analysis in presence ...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Universiti Putra Malaysia
Curated by ChEMBL
Universiti Putra Malaysia
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of 5-LOX in calcium ionophore A23187-stimulated NMRI mouse macrophage assessed as inhibition of LTC4 production preincubated for 60 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human C-terminal His/N-terminal GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus infected Sf9 cells using bi...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research
Curated by ChEMBL
National Organization For Drug Control & Research
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of CDK2/cyclin A expressed in baculovirus infected insect Sf21 cells using [gamma-P32]ATP and histone H1 as substrate after 10 mins by rad...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research
Curated by ChEMBL
National Organization For Drug Control & Research
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of CDK2/cyclin A expressed in baculovirus infected insect Sf21 cells using [gamma-P32]ATP and histone H1 as substrate after 10 mins by rad...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research
Curated by ChEMBL
National Organization For Drug Control & Research
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of CDK2/cyclin A expressed in baculovirus infected insect Sf21 cells using [gamma-P32]ATP and histone H1 as substrate after 10 mins by rad...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of COX1 in human platelets assessed as inhibition of conversion of arachidonic acid to PGE2 preincubated for 15 mins before substrate addi...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research
Curated by ChEMBL
National Organization For Drug Control & Research
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK2/cyclin A expressed in baculovirus infected insect Sf21 cells using [gamma-P32]ATP and histone H1 as substrate after 10 mins by rad...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research
Curated by ChEMBL
National Organization For Drug Control & Research
Curated by ChEMBL
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of CDK2/cyclin A expressed in baculovirus infected insect Sf21 cells using [gamma-P32]ATP and histone H1 as substrate after 10 mins by rad...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research
Curated by ChEMBL
National Organization For Drug Control & Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2/cyclin A expressed in baculovirus infected insect Sf21 cells using [gamma-P32]ATP and histone H1 as substrate after 10 mins by rad...More data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+4nMT: 2°CAssay Description:Assays are performed for 15 min at 30 °C, with 50 µM of P33-ATP in a final volume of 25 µL. The assays are terminated by spotting 20 &...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research
Curated by ChEMBL
National Organization For Drug Control & Research
Curated by ChEMBL
Affinity DataIC50: 2.95E+4nMAssay Description:Inhibition of CDK2/cyclin A expressed in baculovirus infected insect Sf21 cells using [gamma-P32]ATP and histone H1 as substrate after 10 mins by rad...More data for this Ligand-Target Pair
Affinity DataIC50: 2.95E+4nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research
Curated by ChEMBL
National Organization For Drug Control & Research
Curated by ChEMBL
Affinity DataIC50: 2.95E+4nMAssay Description:Inhibition of CDK2/cyclin A expressed in baculovirus infected insect Sf21 cells using [gamma-P32]ATP and histone H1 as substrate after 10 mins by rad...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research
Curated by ChEMBL
National Organization For Drug Control & Research
Curated by ChEMBL
Affinity DataIC50: 3.63E+4nMAssay Description:Inhibition of CDK2/cyclin A expressed in baculovirus infected insect Sf21 cells using [gamma-P32]ATP and histone H1 as substrate after 10 mins by rad...More data for this Ligand-Target Pair
Affinity DataIC50: 4.79E+4nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: 6.18E+4nMT: 2°CAssay Description:Assays are performed for 15 min at 30 °C, with 50 µM of P33-ATP in a final volume of 25 µL. The assays are terminated by spotting 20 &...More data for this Ligand-Target Pair
Affinity DataIC50: 6.61E+4nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: 8.54E+4nMT: 2°CAssay Description:Assays are performed for 15 min at 30 °C, with 50 µM of P33-ATP in a final volume of 25 µL. The assays are terminated by spotting 20 &...More data for this Ligand-Target Pair
Affinity DataIC50: 9.33E+4nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair