Affinity DataIC50: 0.5nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of 5'-TAMRA tagged NRF2 (unknown origin)/human recombinant N-terminal Avi tagged KEAP-1 (321 to 609 residues) expressed in Baculovirus sys...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of 5'-TAMRA tagged NRF2 (unknown origin)/human recombinant N-terminal Avi tagged KEAP-1 (321 to 609 residues) expressed in Baculovirus sys...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of 5'-TAMRA tagged NRF2 (unknown origin)/human recombinant N-terminal Avi tagged KEAP-1 (321 to 609 residues) expressed in Baculovirus sys...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of p70S6K by radiometric filter binding assayMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of 5'-TAMRA tagged NRF2 (unknown origin)/human recombinant N-terminal Avi tagged KEAP-1 (321 to 609 residues) expressed in Baculovirus sys...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 221nMAssay Description:Inhibition of 5'-TAMRA tagged NRF2 (unknown origin)/human recombinant N-terminal Avi tagged KEAP-1 (321 to 609 residues) expressed in Baculovirus sys...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of 5'-TAMRA tagged NRF2 (unknown origin)/human recombinant N-terminal Avi tagged KEAP-1 (321 to 609 residues) expressed in Baculovirus sys...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of 5'-TAMRA tagged NRF2 (unknown origin)/human recombinant N-terminal Avi tagged KEAP-1 (321 to 609 residues) expressed in Baculovirus sys...More data for this Ligand-Target Pair
Affinity DataIC50: 246nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of 5'-TAMRA tagged NRF2 (unknown origin)/human recombinant N-terminal Avi tagged KEAP-1 (321 to 609 residues) expressed in Baculovirus sys...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of 5'-TAMRA tagged NRF2 (unknown origin)/human recombinant N-terminal Avi tagged KEAP-1 (321 to 609 residues) expressed in Baculovirus sys...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of 5'-TAMRA tagged NRF2 (unknown origin)/human recombinant N-terminal Avi tagged KEAP-1 (321 to 609 residues) expressed in Baculovirus sys...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of GSK3-beta in human PC3M cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of GSK3-beta in human PC3M cells by ELISAMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of GSK3-beta in human PC3M cells by ELISAMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of GSK3-beta in human PC3M cells by ELISAMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 660nMAssay Description:Inhibition of GSK3-beta in human PC3M cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 5'-TAMRA tagged NRF2 (unknown origin)/human recombinant N-terminal Avi tagged KEAP-1 (321 to 609 residues) expressed in Baculovirus sys...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of GSK3-beta in human PC3M cells by ELISAMore data for this Ligand-Target Pair