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Found 56 with Last Name = 'vijaykumar' and Initial = 'd'
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50180400(2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-6,2'-...)
Affinity DataKi:  1nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186211(CHEMBL211482 | N-[3'-(5-carbamimidoyl-1H-indol-2-y...)
Affinity DataKi:  3nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186210(2-(2,2'-dihydroxy-5-methyl-5'-ureidomethyl-bipheny...)
Affinity DataKi:  4nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186216(2-(5-fluoro-2,2'-dihydroxy-5'-ureidomethyl-bipheny...)
Affinity DataKi:  5nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14863(({3-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-2...)
Affinity DataKi:  13nM ΔG°:  -44.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186214(CHEMBL380098 | hexanoic acid [3'-(5-carbamimidoyl-...)
Affinity DataKi:  13nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186217(CHEMBL377990 | [5-(5-carbamimidoyl-1H-benzoimidazo...)
Affinity DataKi:  14nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14863(({3-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-2...)
Affinity DataKi:  14nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186212(CHEMBL214351 | N-[3'-(5-carbamimidoyl-1H-indol-2-y...)
Affinity DataKi:  16nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186215(CHEMBL214352 | morpholine-4-carboxylic acid [3'-(5...)
Affinity DataKi:  17nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14880(1-(2,4-dimethoxyphenyl)-3-{[3-(2-hydroxy-3-{1H-pyr...)
Affinity DataKi:  28nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14872(1-(2,6-difluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrr...)
Affinity DataKi:  33nM ΔG°:  -42.3kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14877(3-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  47nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50182959(2-(4-hydroxy-5-phenyl-1H-pyrazol-3-yl)-1H-benzoimi...)
Affinity DataKi:  50nMAssay Description:Binding affinity to F9aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14876(1-(2-chlorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrrolo[...)
Affinity DataKi:  57nM ΔG°:  -40.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14869(1-(2-fluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrrolo[...)
Affinity DataKi:  57nM ΔG°:  -40.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14883(4-[({[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-y...)
Affinity DataKi:  58nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14881(1-(3-acetylphenyl)-3-{[3-(2-hydroxy-3-{1H-pyrrolo[...)
Affinity DataKi:  60nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14868(3-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  61.5nM ΔG°:  -40.7kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14896(1-benzyl-1-hydroxy-3-{[3-(2-hydroxy-3-{1H-pyrrolo[...)
Affinity DataKi:  72nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14879(3-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  88nM ΔG°:  -39.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM14143(2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXA...)
Affinity DataKi:  99nMAssay Description:Binding affinity to F9aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14873(1-(2,4-difluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrr...)
Affinity DataKi:  100nM ΔG°:  -39.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14878(3-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  100nM ΔG°:  -39.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14871(1-(4-fluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrrolo[...)
Affinity DataKi:  110nM ΔG°:  -39.3kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186213(CHEMBL211227 | N-[3'-(5-carbamimidoyl-1H-indol-2-y...)
Affinity DataKi:  120nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14870(1-(3-fluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrrolo[...)
Affinity DataKi:  130nM ΔG°:  -38.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14885(1-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  130nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14887(3-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  155nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14884(1-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  160nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14882(1-(4-acetylphenyl)-3-{[3-(2-hydroxy-3-{1H-pyrrolo[...)
Affinity DataKi:  190nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14892(3-hydroxy-N-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyr...)
Affinity DataKi:  220nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14866(3-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  270nM ΔG°:  -37.1kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14874(1-(3,4-difluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrr...)
Affinity DataKi:  330nM ΔG°:  -36.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14865(1-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  335nM ΔG°:  -36.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14867(1-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  350nM ΔG°:  -36.5kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50182057(2-(5'-fluoro-2,2'-dihydroxy-biphenyl-3-yl)-1H-benz...)
Affinity DataKi:  410nMAssay Description:Inhibition of factor7a in Sprague-Dawley ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14893(3-hydroxy-N-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyr...)
Affinity DataKi:  610nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14864(5-azaindole analog 2 | {[3-(2-hydroxy-3-{1H-pyrrol...)
Affinity DataKi:  800nM ΔG°:  -34.4kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14875(1-(3,5-difluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrr...)
Affinity DataKi:  830nM ΔG°:  -34.4kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14894(2-hydroxy-N-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyr...)
Affinity DataKi:  850nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14890(5-azaindole analog 28 | N-{[3-(2-hydroxy-3-{1H-pyr...)
Affinity DataKi:  2.00E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14863(({3-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-2...)
Affinity DataKi:  2.70E+3nM ΔG°:  -31.5kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14886(3-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  2.70E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14895(5-azaindole analog 33 | N-{[3-(2-hydroxy-3-{1H-pyr...)
Affinity DataKi:  2.80E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14863(({3-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-2...)
Affinity DataKi:  3.60E+3nM ΔG°:  -30.8kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14891(2-(2,6-difluorophenyl)-N-{[3-(2-hydroxy-3-{1H-pyrr...)
Affinity DataKi:  9.50E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14888(5-azaindole analog 26 | N-{[3-(2-hydroxy-3-{1H-pyr...)
Affinity DataKi:  1.70E+4nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50182056(3-(1H-benzoimidazol-2-yl)-biphenyl-2,2'-diol | CHE...)
Affinity DataKi:  3.70E+4nMAssay Description:Inhibition of factor7a in Sprague-Dawley ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14864(5-azaindole analog 2 | {[3-(2-hydroxy-3-{1H-pyrrol...)
Affinity DataKi:  4.65E+4nM ΔG°:  -24.5kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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