Affinity DataKi: 50nMAssay Description:Irreversible binding affinity to recombinant human PKM2 expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetPyruvate kinase PKLR(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research Ahmedabad
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research Ahmedabad
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Mycobacterium lufuMore data for this Ligand-Target Pair
Affinity DataKi: 3.53E+3nMAssay Description:Binding affinity to PKM2 (unknown origin) assessed as oxidation of beta-NADH by spectrophotometry based LDH coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.53E+3nMAssay Description:Binding affinity to PKM2 (unknown origin) assessed as oxidation of beta-NADH by spectrophotometry based LDH coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.53E+3nMAssay Description:Binding affinity to PKM2 (unknown origin) assessed as oxidation of beta-NADH by spectrophotometry based LDH coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.53E+3nMAssay Description:Binding affinity to PKM2 (unknown origin) assessed as oxidation of beta-NADH by spectrophotometry based LDH coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.53E+3nMAssay Description:Binding affinity to PKM2 (unknown origin) assessed as oxidation of beta-NADH by spectrophotometry based LDH coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 1.65E+4nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 1.16E+5nMAssay Description:Binding affinity to Leishmania mexicana PKMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+5nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+5nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 9.00E+5nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+6nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-L)More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 2.20E+6nMAssay Description:Inhibition of rat liver pyruvate kinase (PK-L) at 3.6 mMMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+6nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-K)More data for this Ligand-Target Pair
Affinity DataKi: 2.20E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 2.90E+6nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-K)More data for this Ligand-Target Pair
Affinity DataKi: 3.70E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+6nMAssay Description:Inhibitory constant for inhibition of pyruvate kinase obtained from rat liver (PK-L) was determined using ADP as competitive inhibitorMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+6nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-K) at 6.7 mMMore data for this Ligand-Target Pair
Affinity DataKi: 4.30E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M) at 10 mMMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+6nMAssay Description:Inhibition of rat liver pyruvate kinase (PK-L); (relative inhibitory potency)More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M) at 6.7 mMMore data for this Ligand-Target Pair
Affinity DataKi: 5.40E+6nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-K)More data for this Ligand-Target Pair
Affinity DataKi: 7.00E+6nMAssay Description:Inhibitory constant for inhibition of pyruvate kinase obtained from rat liver (PK-L) was determined using ADP as competitive inhibitorMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M) at 6.7 mMMore data for this Ligand-Target Pair
Affinity DataKi: 7.50E+6nMAssay Description:Inhibitory constant for inhibition of pyruvate kinase obtained from rat liver (PK-L) was determined using ADP as competitive inhibitorMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+6nMAssay Description:Michaelis-Menten constant for inhibition of rat kidney pyruvate kinase (PK-K)More data for this Ligand-Target Pair
Affinity DataKi: 8.40E+6nMAssay Description:Inhibitory constant for inhibition of pyruvate kinase obtained from rat liver (PK-L) was determined using ADP as competitive inhibitorMore data for this Ligand-Target Pair
Affinity DataKi: 9.30E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 1.09E+7nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-K) at 6.7 mMMore data for this Ligand-Target Pair
Affinity DataKi: 3.20E+7nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-K)More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of methicillin-resistant Staphylococcus aureus 252 pyruvate kinase by LDH assayMore data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of methicillin-resistant Staphylococcus aureus pyruvate kinase by coupled lactate dehydrogenase continuous assayMore data for this Ligand-Target Pair