Compile Data Set for Download or QSAR
Report error Found 88 Enz. Inhib. hit(s) with all data for entry = 1686
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13390BDBM13390(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50: 0.190nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13389BDBM13389(CHEMBL41748 | 4-{[(4-cyanophenyl)methoxy](1-methyl...)
Affinity DataIC50: 0.300nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13384BDBM13384(4-{[(R)-(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)...)
Affinity DataIC50: 0.350nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13405BDBM13405(3-(3-chlorophenyl)-4-{[(4-cyano-3-fluorophenyl)(1-...)
Affinity DataIC50: 0.440nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13415BDBM13415(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50: 0.610nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13388BDBM13388(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50: 0.690nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13383BDBM13383(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50: 0.75nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13418BDBM13418(N-(3-chlorophenyl)-5-cyano-2-{[(4-cyanophenyl)(1-m...)
Affinity DataIC50: 0.75nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13406BDBM13406(3-(3-chlorophenyl)-4-{[(4-cyano-2-fluorophenyl)(1-...)
Affinity DataIC50: 0.770nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13375BDBM13375(4-({[4-chloro-2-(3-chlorophenyl)phenyl]methoxy}(1-...)
Affinity DataIC50: 0.800nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13393BDBM13393(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50: 0.840nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13382BDBM13382(CHEMBL158553 | 3-(3-chlorophenyl)-4-{[(4-cyanophen...)
Affinity DataIC50: 0.870nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13386BDBM13386(3-(2H-1,3-benzodioxol-5-yl)-4-{[(4-cyanophenyl)(1-...)
Affinity DataIC50: 0.870nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13412BDBM13412(N-(5-cyano-2-{[(4-cyanophenyl)(1-methyl-1H-imidazo...)
Affinity DataIC50: 0.880nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13377BDBM13377(4-({[4-chloro-2-(3-methoxyphenyl)phenyl]methoxy}(1...)
Affinity DataIC50: 0.910nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13380BDBM13380(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50: 0.940nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13391BDBM13391(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50: 0.960nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13404BDBM13404(4-{[(3-chloro-4-cyanophenyl)(1-methyl-1H-imidazol-...)
Affinity DataIC50: 0.970nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13395BDBM13395(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50: 0.980nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13413BDBM13413(A313326 Analogue 60b)
Affinity DataIC50: 1nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13396BDBM13396(4-({[2-(3-methoxyphenyl)-4-nitrophenyl]methoxy}(1-...)
Affinity DataIC50: 1.10nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13387BDBM13387(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50: 1.10nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13407BDBM13407(3-(3-chlorophenyl)-4-{[(1-methyl-1H-imidazol-5-yl)...)
Affinity DataIC50: 1.10nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13378BDBM13378(4-({[4-chloro-2-(3-ethoxyphenyl)phenyl]methoxy}(1-...)
Affinity DataIC50: 1.10nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13394BDBM13394(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50: 1.10nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13392BDBM13392(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50: 1.20nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13379BDBM13379(CHEMBL127296 | 4-{[(4-cyanophenyl)(1-methyl-1H-imi...)
Affinity DataIC50: 1.30nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13402BDBM13402(4-({[4-formyl-2-(3-methoxyphenyl)phenyl]methoxy}(1...)
Affinity DataIC50: 1.60nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13409BDBM13409(3-(2H-1,3-benzodioxol-5-yl)-4-{[(4-cyanophenyl)(1,...)
Affinity DataIC50: 1.60nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13403BDBM13403(4-{[(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)met...)
Affinity DataIC50: 2nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13408BDBM13408(3-(3-chlorophenyl)-4-{[(4-cyanophenyl)(1,2-dimethy...)
Affinity DataIC50: 2nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13417BDBM13417(5-cyano-2-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5...)
Affinity DataIC50: 2.20nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13414BDBM13414(N-(5-cyano-2-{[(4-cyanophenyl)(1-methyl-1H-imidazo...)
Affinity DataIC50: 2.60nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13410BDBM13410(3-(3-chlorophenyl)-4-{[(4-cyanophenyl)(1,3-thiazol...)
Affinity DataIC50: 4nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13376BDBM13376(4-({[4-chloro-2-(4-chlorophenyl)phenyl]methoxy}(1-...)
Affinity DataIC50: 4.80nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13416BDBM13416(N-(5-cyano-2-{[(4-cyanophenyl)(1-methyl-1H-imidazo...)
Affinity DataIC50: 5nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13381BDBM13381(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50: 5.20nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13374BDBM13374(4-({[4-chloro-2-(2-chlorophenyl)phenyl]methoxy}(1-...)
Affinity DataIC50: 8.90nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13399BDBM13399(N-(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)m...)
Affinity DataIC50: 11nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13400BDBM13400(methyl 4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-...)
Affinity DataIC50: 13nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13411BDBM13411(3-(2H-1,3-benzodioxol-5-yl)-4-{[(4-chloropyridin-3...)
Affinity DataIC50: 15nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Bovine)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13389BDBM13389(CHEMBL41748 | 4-{[(4-cyanophenyl)methoxy](1-methyl...)
Affinity DataIC50: 18nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13385BDBM13385(4-{[(S)-(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)...)
Affinity DataIC50: 21nMpH: 7.0 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13398BDBM13398(N-(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)m...)
Affinity DataIC50: 35nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13397BDBM13397(4-({[4-amino-2-(3-methoxyphenyl)phenyl]methoxy}(1-...)
Affinity DataIC50: 40nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Bovine)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13413BDBM13413(A313326 Analogue 60b)
Affinity DataIC50: 65nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13401BDBM13401(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50: 83nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Bovine)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13414BDBM13414(N-(5-cyano-2-{[(4-cyanophenyl)(1-methyl-1H-imidazo...)
Affinity DataIC50: 100nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Bovine)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13404BDBM13404(4-{[(3-chloro-4-cyanophenyl)(1-methyl-1H-imidazol-...)
Affinity DataIC50: 170nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Bovine)
Globe Pharmaceutical R and Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13412BDBM13412(N-(5-cyano-2-{[(4-cyanophenyl)(1-methyl-1H-imidazo...)
Affinity DataIC50: 220nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
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