Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 50034521
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50063266(6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]-5HT from human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM25876(4,4-dimethyl-1-{4-[4-(quinolin-2-yl)piperazin-1-yl...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM25869(2-{4-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]but...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363815(CHEMBL1945686)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM25873(8-{4-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]but...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50014407(2-(piperazin-1-yl)quinoline | 2-Piperazin-1-yl-qui...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-5HT from human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM25871(1-{4-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]but...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM25874(2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}-2,3-d...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM25875(8-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}-8-aza...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363810(CHEMBL1945681)
Affinity DataKi:  221nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50014407(2-(piperazin-1-yl)quinoline | 2-Piperazin-1-yl-qui...)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM25872(2-{3-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]pro...)
Affinity DataKi:  275nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363806(CHEMBL1945475)
Affinity DataKi:  711nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363808(CHEMBL1945679)
Affinity DataKi:  777nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363809(CHEMBL1945680)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363813(CHEMBL1945684)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363811(CHEMBL1945682)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363814(CHEMBL1945685)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363807(CHEMBL1945678)
Affinity DataKi:  1.06E+4nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363812(CHEMBL1945683)
Affinity DataKi:  5.90E+4nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM25869(2-{4-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]but...)
Affinity DataIC50:  33.4nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM25871(1-{4-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]but...)
Affinity DataIC50:  50nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM25873(8-{4-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]but...)
Affinity DataIC50:  75nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM25872(2-{3-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]pro...)
Affinity DataIC50:  80nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM25874(2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}-2,3-d...)
Affinity DataIC50:  95.5nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM25875(8-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}-8-aza...)
Affinity DataIC50:  112nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM25876(4,4-dimethyl-1-{4-[4-(quinolin-2-yl)piperazin-1-yl...)
Affinity DataIC50:  146nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363815(CHEMBL1945686)
Affinity DataIC50:  171nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363806(CHEMBL1945475)
Affinity DataIC50:  268nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363811(CHEMBL1945682)
Affinity DataIC50:  616nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363810(CHEMBL1945681)
Affinity DataIC50:  807nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363807(CHEMBL1945678)
Affinity DataIC50:  921nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363808(CHEMBL1945679)
Affinity DataIC50:  1.35E+3nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363813(CHEMBL1945684)
Affinity DataIC50:  2.80E+3nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363812(CHEMBL1945683)
Affinity DataIC50:  4.13E+3nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363814(CHEMBL1945685)
Affinity DataIC50:  1.88E+4nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50363809(CHEMBL1945680)
Affinity DataIC50:  2.59E+4nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed