Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 5676
TargetCyclin-dependent kinase 2(Human)
Moffitt Cancer Center

LigandPNGBDBM50088360(Purpurogallin | purpurogalline | 2,3,4,6-tetrahydr...)
Affinity DataIC50: 1.70E+4nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
Moffitt Cancer Center

LigandPNGBDBM92563(Hit compound, 4)
Affinity DataIC50: 4.50E+4nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Moffitt Cancer Center

LigandPNGBDBM67612(cid_238065 | SMR000304390 | 2-pyridin-2-ylindene-1...)
Affinity DataIC50: 4.60E+4nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Moffitt Cancer Center

LigandPNGBDBM92564(Hit compound, 5)
Affinity DataIC50: 5.30E+4nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Moffitt Cancer Center

LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 1.30E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Moffitt Cancer Center

LigandPNGBDBM92562(Hit compound, 3)
Affinity DataIC50: 1.50E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Moffitt Cancer Center

LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 1.50E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Moffitt Cancer Center

LigandPNGBDBM92565(Hit compound, 7)
Affinity DataIC50: 1.50E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Moffitt Cancer Center

LigandPNGBDBM92568(Hit compound, 12)
Affinity DataIC50: 1.50E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Moffitt Cancer Center

LigandPNGBDBM50651(cid_246666 | 2,6-bis(azanyl)-1,5-bis(chloranyl)ant...)
Affinity DataIC50: 1.50E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Moffitt Cancer Center

LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataIC50: 1.50E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Moffitt Cancer Center

LigandPNGBDBM52831(cid_5385177 | MLS000757168 | SMR000529027 | Hit co...)
Affinity DataIC50: 1.50E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed