Compile Data Set for Download or QSAR
Report error Found 14 of affinity data for UniProtKB/TrEMBL: A0A3A5LBF0
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 161472BDBM161472(US9108978, 2.02)
Affinity DataKi:  30nM ΔG°:  -44.7kJ/mole IC50: 203nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent

TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 92383BDBM92383(Biotin triazole, 14)
Affinity DataKi:  90nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 161468BDBM161468(US9108978, 6.09)
Affinity DataKi:  90nM ΔG°:  -41.8kJ/mole IC50: 530nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 161470BDBM161470(US9108978, 4.01)
Affinity DataKi:  660nM ΔG°:  -36.7kJ/mole IC50: 4.00E+3nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 92378BDBM92378(Biotin triazole, 5)
Affinity DataKi:  1.17E+3nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 92382BDBM92382(Biotin triazole, 13)
Affinity DataKi:  1.17E+3nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 161469BDBM161469(US9108978, 6.07)
Affinity DataKi:  1.17E+3nM ΔG°:  -35.2kJ/mole IC50: 7.00E+3nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent

TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 161467BDBM161467(US9108978, 3.25)
Affinity DataKi:  1.83E+3nM ΔG°:  -34.1kJ/mole IC50: 1.16E+4nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent

TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 92385BDBM92385(Biotin triazole, 16)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 92384BDBM92384(Biotin triazole, 15)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 92381BDBM92381(Biotin triazole, 12)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 92380BDBM92380(Biotin triazole, 11)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 92379BDBM92379(Biotin triazole, 10)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 161471BDBM161471(US9108978, 6.34)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/mole IC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent