Compile Data Set for Download or QSAR
Report error Found 118 of affinity data for UniProtKB/TrEMBL: Q9GZV3
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87576(SMR000658847 | MLS001100779 | cid_24793407 | N-[(3...)
Affinity DataIC50: 18.9nMAssay Description:Data Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC) Center Affiliation: Johns Hopkins University, School of Medicine Screening ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50451447(CHEMBL4217988)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]hemicholinium-3 from recombinant human choline transporter after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067207(CHEMBL3304438)
Affinity DataIC50: 72nMAssay Description:Inhibition of [3H]choline uptake at human choline transporter expressed in HEK293 cells preincubated for 15 mins followed by [3H]choline addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067207(CHEMBL3304438)
Affinity DataIC50: 90nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067202(CHEMBL1872483)
Affinity DataIC50: 100nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50451447(CHEMBL4217988)
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]hemicholinium-3 from recombinant human choline transporter after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067202(CHEMBL1872483)
Affinity DataIC50: 240nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067207(CHEMBL3304438)
Affinity DataIC50: 270nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50196412(CHEMBL3933906)
Affinity DataIC50: 270nMAssay Description:Inhibition of [3H]choline uptake at human choline transporter expressed in HEK293 cells preincubated for 15 mins followed by [3H]choline addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2018
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87575(N-[(4,5-dimethyl-1,3-thiazol-2-yl)methyl]-4-methox...)
Affinity DataIC50: 303nMAssay Description:Data Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC) Center Affiliation: Johns Hopkins University, School of Medicine Screening ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87579(cid_1744440 | N-[4-[(2,6-dimethylpyrimidin-4-yl)su...)
Affinity DataIC50: 447nMAssay Description:Data Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC) Center Affiliation: Johns Hopkins University, School of Medicine Screening ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50196416(CHEMBL3899143)
Affinity DataIC50: 467nMAssay Description:Inhibition of [3H]choline uptake at human choline transporter expressed in HEK293 cells preincubated for 15 mins followed by [3H]choline addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2018
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067209(CHEMBL3303792)
Affinity DataIC50: 530nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87576(SMR000658847 | MLS001100779 | cid_24793407 | N-[(3...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50196414(CHEMBL3959257)
Affinity DataIC50: 640nMAssay Description:Inhibition of [3H]choline uptake at human choline transporter expressed in HEK293 cells preincubated for 15 mins followed by [3H]choline addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2018
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87575(N-[(4,5-dimethyl-1,3-thiazol-2-yl)methyl]-4-methox...)
Affinity DataIC50: 760nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067209(CHEMBL3303792)
Affinity DataIC50: 760nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87581(MLS001081265 | cid_24979281 | SMR000716369 | 2,4-b...)
Affinity DataIC50: 864nMAssay Description:Data Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC) Center Affiliation: Johns Hopkins University, School of Medicine Screening ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067203(CHEMBL3182315)
Affinity DataIC50: 910nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50326218(N-{1-[3-(3-Oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)pr...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to human choline transporter (CHT1) by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50326219(CHEMBL1242950 | CHEMBL2206334 | 4-(4-butylpiperidi...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to human choline transporter (CHT1) by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067199(CHEMBL3187862)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067208(CHEMBL3303292)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87569(N-(1-phenylethyl)-4-{[1-(pyridin-2-ylmethyl)piperi...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067205(CHEMBL3183447)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067203(CHEMBL3182315)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067200(CHEMBL3187348)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067206(CHEMBL3188567)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067210(CHEMBL3303803)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM89137(N-(furan-2-ylmethyl)-2-piperidin-1-yl-quinazolin-4...)
Affinity DataEC50:  1.79E+3nMAssay Description:Data Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC) Center Affiliation: Johns Hopkins University, School of Medicine Screening ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87569(N-(1-phenylethyl)-4-{[1-(pyridin-2-ylmethyl)piperi...)
Affinity DataIC50: 1.79E+3nMAssay Description:Data Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC) Center Affiliation: Johns Hopkins University, School of Medicine Screening ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50196411(CHEMBL3923550)
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of [3H]choline uptake at human choline transporter expressed in HEK293 cells preincubated for 15 mins followed by [3H]choline addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2018
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067204(CHEMBL3183383)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87572(N-(2,3-dihydro-1H-inden-1-yl)-4-methoxy-3-[(1-prop...)
Affinity DataIC50: 2.12E+3nMAssay Description:Data Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC) Center Affiliation: Johns Hopkins University, School of Medicine Screening ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067205(CHEMBL3183447)
Affinity DataIC50: 2.13E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067201(CHEMBL3186365)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87570(2,4-dichloro-N-{4-[(2-quinoxalinylamino)sulfonyl]p...)
Affinity DataIC50: 2.82E+3nMAssay Description:Data Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC) Center Affiliation: Johns Hopkins University, School of Medicine Screening ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87574(cid_24793028 | MLS001082585 | N-[2-(cyclohexen-1-y...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50400797(CHEMBL2203622)
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at CHT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50196415(CHEMBL3970338)
Affinity DataIC50: 3.35E+3nMAssay Description:Inhibition of [3H]choline uptake at human choline transporter expressed in HEK293 cells preincubated for 15 mins followed by [3H]choline addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2018
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87572(N-(2,3-dihydro-1H-inden-1-yl)-4-methoxy-3-[(1-prop...)
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067199(CHEMBL3187862)
Affinity DataIC50: 3.48E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87578(SMR000664527 | MLS001101393 | N-(2-phenylethyl)-3-...)
Affinity DataIC50: 3.76E+3nMAssay Description:Data Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC) Center Affiliation: Johns Hopkins University, School of Medicine Screening ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM95194(2-chloro-4-nitro-N-[4-(2-pyridinylsulfamoyl)phenyl...)
Affinity DataIC50: 3.85E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067206(CHEMBL3188567)
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87578(SMR000664527 | MLS001101393 | N-(2-phenylethyl)-3-...)
Affinity DataIC50: 4.22E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87577(4-methoxy-3-(1-propan-2-ylpiperidin-4-yl)oxy-N-(1-...)
Affinity DataIC50: 4.47E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067208(CHEMBL3303292)
Affinity DataIC50: 4.54E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM87060(SMR000715032 | N-(4-methylcyclohexyl)-3-(4-methylp...)
Affinity DataIC50: 4.68E+3nMAssay Description:Data Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC) Center Affiliation: Johns Hopkins University, School of Medicine Screening ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetHigh affinity choline transporter 1(Human)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50067200(CHEMBL3187348)
Affinity DataIC50: 4.93E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
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