Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [489-587,G537V,H558K,V571A]'
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122997BDBM122997(US8742158, EX 19)
Affinity DataIC50: 0.290nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122988BDBM122988(US8742158, EX. 41)
Affinity DataIC50: 0.336nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 50422052BDBM50422052(L-700417 | CHEMBL109952)
Affinity DataKi:  0.370nMAssay Description:Inhibition of recombinant HIV protease expressed in inclusion bodies of Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122987BDBM122987(US8742158, EX. 46)
Affinity DataIC50: 0.372nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 50067593BDBM50067593(CHEBI:44032 | Crixivan | Indinavir | L-735524 | MK...)
Affinity DataKi:  0.380nMAssay Description:Inhibition of recombinant HIV protease expressed in inclusion bodies of Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122977BDBM122977(US8742158, EX 58)
Affinity DataIC50: 0.436nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122978BDBM122978(US8742158, EX 61)
Affinity DataIC50: 0.465nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122985BDBM122985(US8742158, EX. 44)
Affinity DataIC50: 0.471nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122993BDBM122993(US8742158, EX 36)
Affinity DataIC50: 0.503nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122980BDBM122980(US8742158, EX. 7)
Affinity DataIC50: 0.507nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122979BDBM122979(US8742158, EX 62)
Affinity DataIC50: 0.510nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122991BDBM122991(US8742158, EX. 40)
Affinity DataIC50: 0.567nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122990BDBM122990(US8742158, EX. 39)
Affinity DataIC50: 0.580nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122983BDBM122983(US8742158, EX. 9)
Affinity DataIC50: 0.580nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123000BDBM123000(US8742158, EX 17)
Affinity DataIC50: 0.599nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122996BDBM122996(US8742158, EX 18)
Affinity DataIC50: 0.600nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122976BDBM122976(US8742158, EX 57)
Affinity DataIC50: 0.601nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122986BDBM122986(US8742158, EX. 45)
Affinity DataIC50: 0.615nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122989BDBM122989(US8742158, EX. 42)
Affinity DataIC50: 0.618nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122980BDBM122980(US8742158, EX. 7)
Affinity DataIC50: 0.652nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122994BDBM122994(US8742158, EX 37)
Affinity DataIC50: 0.683nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122992BDBM122992(US8742158, EX. 43)
Affinity DataIC50: 0.836nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122974BDBM122974(US8742158, EX 55)
Affinity DataIC50: 0.878nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123002BDBM123002(US8742158, EX 32)
Affinity DataIC50: 0.899nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122995BDBM122995(US8742158, EX 38)
Affinity DataIC50: 0.920nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123012BDBM123012(US8742158, EX 63)
Affinity DataIC50: 0.938nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123003BDBM123003(US8742158, EX 34)
Affinity DataIC50: 0.963nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122998BDBM122998(US8742158, EX 15)
Affinity DataIC50: 0.995nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122981BDBM122981(US8742158, EX. 33)
Affinity DataIC50: 1.01nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122982BDBM122982(US8742158, EX. 8)
Affinity DataIC50: 1.07nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122984BDBM122984(US8742158, EX. 10)
Affinity DataIC50: 1.08nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123009BDBM123009(US8742138, 37 | US8742158, EX 21)
Affinity DataIC50: 1.29nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123010BDBM123010(US8742138, 38 | US8742158, EX 22)
Affinity DataIC50: 1.35nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123008BDBM123008(US8742158, EX 20)
Affinity DataIC50: 1.42nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 84460BDBM84460(HIV-1 PR Inhibitor, compound 6)
Affinity DataKi:  1.70nM IC50: 6nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122999BDBM122999(US8742158, EX 16)
Affinity DataIC50: 2.02nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123007BDBM123007(US8742158, EX 30)
Affinity DataIC50: 2.15nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123005BDBM123005(US8742158, EX 27)
Affinity DataIC50: 2.55nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 50462131BDBM50462131(CHEMBL2182010)
Affinity DataKi:  2.70nMAssay Description:Inhibition of HIV proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123014BDBM123014(US8742158, EX 25)
Affinity DataIC50: 2.88nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123004BDBM123004(US8742158, EX 35)
Affinity DataIC50: 3.01nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123015BDBM123015(US8742158, EX 26)
Affinity DataIC50: 3.31nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123001BDBM123001(US8742158, EX 31)
Affinity DataIC50: 3.66nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123006BDBM123006(US8742158, EX 29)
Affinity DataIC50: 3.81nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 84461BDBM84461(HIV-1 PR Inhibitor, compound 8)
Affinity DataKi:  4nM IC50: 13nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123011BDBM123011(US8742158, EX 23)
Affinity DataIC50: 4.12nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122973BDBM122973(US8742158, EX 48)
Affinity DataIC50: 4.95nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 123013BDBM123013(US8742158, EX 24)
Affinity DataIC50: 5.21nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 122975BDBM122975(US8742158, EX 56)
Affinity DataIC50: 5.90nMAssay Description:This is a fluorometric assay based on the cleavage by protease of a substrate carrying a donor group (EDANS) and an acceptor group (DABCYL) on each s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Taimed Biologies

US Patent
LigandChemical structure of BindingDB Monomer ID 84461BDBM84461(HIV-1 PR Inhibitor, compound 8)
Affinity DataKi:  9.70nM IC50: 17nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2012
Entry Details Article
PubMed
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