Affinity DataKi: 19nMAssay Description:Binding affinity to human IDO1 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Binding affinity to human TDO assessed as inhibition constant by Cornhish-Bowden methodMore data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Binding affinity to human TDO assessed as inhibition constant by Cornhish-Bowden methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.98E+3nMAssay Description:Binding affinity to human IDO1 assessed as inhibition constant by Cornhish-Bowden methodMore data for this Ligand-Target Pair
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
National Chung-Hsing University
Curated by ChEMBL
National Chung-Hsing University
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Binding affinity of the compound against phospholipase A2 of Naja mocambique mocambiqueMore data for this Ligand-Target Pair
Affinity DataKi: 4.48E+3nMAssay Description:Binding affinity to human IDO1 assessed as inhibition constant by Cornhish-Bowden methodMore data for this Ligand-Target Pair
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
National Chung-Hsing University
Curated by ChEMBL
National Chung-Hsing University
Curated by ChEMBL
Affinity DataKi: 1.10E+4nMAssay Description:Binding affinity of the compound against phospholipase A2 of Naja mocambique mocambiqueMore data for this Ligand-Target Pair
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
National Chung-Hsing University
Curated by ChEMBL
National Chung-Hsing University
Curated by ChEMBL
Affinity DataKi: 1.50E+4nMAssay Description:Binding affinity of the compound against phospholipase A2 of Naja mocambique mocambiqueMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+4nMAssay Description:Binding affinity to human IDO1 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 0.316nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at mouse CCR4More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 9.60nMAssay Description:Inhibition of human TDOMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Effective concentration required to inhibit HIV-1 induced cytopathicity by 50% in CEM cellsMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University of Maryland
Curated by ChEMBL
University of Maryland
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of rat testicular microsomal Cytochrome P450 17A1More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Maryland
Curated by ChEMBL
University of Maryland
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human testicular microsomal Cytochrome P450 17A1More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Maryland
Curated by ChEMBL
University of Maryland
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human testicular microsomal Cytochrome P450 17A1More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University of Maryland
Curated by ChEMBL
University of Maryland
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of rat testicular microsomal Cytochrome P450 17A1More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Antagonist activity at human CCR4 expressed in CHO cells coexpressing CD4+ assessed as inhibition of CCL22 induced Ca2+ mobilizationMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University of Maryland
Curated by ChEMBL
University of Maryland
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of rat testicular microsomal Cytochrome P450 17A1More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Maryland
Curated by ChEMBL
University of Maryland
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of human testicular microsomal Cytochrome P450 17A1More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human TDO (19 to 388 aa) expressed in Escherichia coli Transetta (DE3) by nanodrop 2000c spectrophotometric analysisMore data for this Ligand-Target Pair