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Found 72 with Last Name = 'la sala' and Initial = 'g'
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089575(CHEMBL3578214)
Affinity DataKi:  70nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089569(CHEMBL3578215)
Affinity DataKi:  95nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089576(CHEMBL3578213)
Affinity DataKi:  360nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089573(CHEMBL3578218)
Affinity DataKi:  870nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089577(CHEMBL3578212)
Affinity DataKi:  900nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089568(CHEMBL3578219)
Affinity DataKi:  995nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089581(CHEMBL3578210)
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089574(CHEMBL3578204)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089570(CHEMBL3578216)
Affinity DataKi:  1.49E+3nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089565(CHEMBL3578221)
Affinity DataKi:  1.63E+3nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089526(CHEMBL3578224)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089523(CHEMBL3578225)
Affinity DataKi:  2.25E+3nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089571(CHEMBL3578217)
Affinity DataKi:  3.35E+3nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50354486(CHEMBL411043)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50343431(1-(2-Chloro-2-phenylethyl)-6-[(2-morpholin-4-yleth...)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50343426(1-(2-Chloro-2-phenylethyl)-6-[(2-morpholin-4-yleth...)
Affinity DataKi:  8.15E+3nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089566(CHEMBL3578220)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089534(CHEMBL3578222)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089531(CHEMBL3578223)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089579(CHEMBL3578208)
Affinity DataKi:  1.25E+4nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089578(CHEMBL3578211)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50343428(1-(2-Chloro-2-phenylethyl)-N-(4-fluorobenzyl)-6-[(...)
Affinity DataKi:  1.55E+4nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089580(CHEMBL3578209)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238556(CHEMBL4093029)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of 5-HT uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238557(CHEMBL4103207)
Affinity DataIC50:  1nMAssay Description:Inhibition of noradrenaline uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238562(CHEMBL4084295)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of 5-HT uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238574(CHEMBL4092051)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238573(CHEMBL4062592)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238572(CHEMBL4065362)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of noradrenaline uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238569(CHEMBL4075447)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238568(CHEMBL4100744)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238578(CHEMBL4071239)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of 5-HT uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238558(CHEMBL4075028)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238563(Benzoimidazole-1-Carboxylic Acid Hexylamide | CHEM...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of noradrenaline uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238570(CHEMBL4089655)
Affinity DataIC50:  7nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238577(CHEMBL4096883)
Affinity DataIC50:  7nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238576(CHEMBL4076230)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238561(CHEMBL4101140)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238565(CHEMBL4095461)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238554(CHEMBL4094489)
Affinity DataIC50:  14nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238566(CHEMBL4075846)
Affinity DataIC50:  15nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431275(CARMOFUR | Carm-ofur | Mifurol | med.21724, Compou...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238571(CHEMBL4099796)
Affinity DataIC50:  21nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238555(CHEMBL4076865)
Affinity DataIC50:  23nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238567(CHEMBL4075647)
Affinity DataIC50:  29nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238575(CHEMBL4077199)
Affinity DataIC50:  56nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238559(CHEMBL4090927)
Affinity DataIC50:  68nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238568(CHEMBL4100744)
Affinity DataIC50:  76nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMajor prion protein(Mus musculus)
Scuola Internazionale Superiore Di Studi Avanzati (Sissa)

Curated by ChEMBL
LigandPNGBDBM50015214(6-chloro-2-methoxy-9-acridinyl(4-diethylamino-1-me...)
Affinity DataIC50:  95nMAssay Description:Synergistic anti-prion activity of mouse ScN2a cells infected with RML prion assessed as reduction of RML accumulation by isobologram analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431275(CARMOFUR | Carm-ofur | Mifurol | med.21724, Compou...)
Affinity DataIC50:  191nMAssay Description:Inhibition of acid ceramidase in human A375 cells using fluorogenic substrate Rbm-14-12 preincubated for 2 hrs followed by substrate addition measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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