TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Activation of human Kv7.4 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 87nMAssay Description:Agonist activity at Kv7.4 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Activation of human Kv7.4 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 320nMAssay Description:Agonist activity at Kv7.4 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 625nMAssay Description:Activation of human Kv7.4 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 660nMAssay Description:Agonist activity at Kv7.4 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 780nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 890nMAssay Description:Activation of human homomeric KCNQ4 expressed in CHOK1 cells at -10 mV by whole cell patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 910nMAssay Description:Agonist activity at Kv7.4 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 1.42E+3nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 1.60E+3nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 1.98E+3nMAssay Description:Activation of human Kv7.4 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 2.03E+3nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 2.40E+3nMAssay Description:Positive modulatory activity at voltage-gated K channel 7.4 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 4.00E+3nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 5.90E+3nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 6.40E+3nMAssay Description:Agonist activity at human KCNQ4 channel expressed in CHO cells assessed as increase in outward current by patch clamp electrophysiology methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of KCNQ4 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assay relative to c...More data for this Ligand-Target Pair