Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with Target = 'Toxopain-2'
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271690BDBM50271690(CHEMBL222649)
Affinity DataIC50: 2nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271714BDBM50271714(CHEMBL4126546)
Affinity DataIC50: 110nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271696BDBM50271696(CHEMBL4125776)
Affinity DataIC50: 120nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 232239BDBM232239(N-3-trifluoromethylbenzoyl-L-leucine-glycine nitri...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271685BDBM50271685(CHEMBL4128887)
Affinity DataIC50: 160nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271681BDBM50271681(CHEMBL4129611)
Affinity DataIC50: 180nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271682BDBM50271682(CHEMBL4130087)
Affinity DataIC50: 250nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19861BDBM19861((2S)-N-(cyanomethyl)-4-methyl-2-(phenylformamido)p...)
Affinity DataIC50: 350nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271697BDBM50271697(CHEMBL4128244)
Affinity DataIC50: 360nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271688BDBM50271688(CHEMBL4130249)
Affinity DataIC50: 400nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271709BDBM50271709(CHEMBL4126824)
Affinity DataIC50: 420nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271686BDBM50271686(CHEMBL4126741)
Affinity DataIC50: 530nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271698BDBM50271698(CHEMBL4128116)
Affinity DataIC50: 540nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271713BDBM50271713(CHEMBL4129822)
Affinity DataIC50: 660nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271712BDBM50271712(CHEMBL4128869)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271693BDBM50271693(CHEMBL4126455)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271691BDBM50271691(CHEMBL4129884)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271692BDBM50271692(CHEMBL4126611)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31993BDBM31993(Dipeptidyl nitrile inhibitor, 26)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271711BDBM50271711(CHEMBL4129022)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271689BDBM50271689(CHEMBL4130028)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271683BDBM50271683(CHEMBL4127618)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271695BDBM50271695(CHEMBL4127142)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271694BDBM50271694(CHEMBL4127007)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271710BDBM50271710(CHEMBL4126675)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271684BDBM50271684(CHEMBL4130234)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271687BDBM50271687(CHEMBL4128058)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed