Affinity DataIC50: 0.0501nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0794nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 0.316nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Antagonist activity at human P2Y12 receptor assessed as ADP-induced human platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.398nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at human P2Y12 receptor assessed as ADP-induced human platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium influxMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.51nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.16nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as effect on BzATP-induced Yo-Pro uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 3.16nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 3.98nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.31nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium influxMore data for this Ligand-Target Pair
Affinity DataIC50: 6.31nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 6.31nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.94nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as effect on BzATP-induced Yo-Pro uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 7.94nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human P2X7 receptor expressed in human U373 cells assessed as inhibition of BzATP-induced Yo-Pro uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as effect on BzATP-induced Yo-Pro uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as effect on BzATP-induced Yo-Pro uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMAssay Description:Antagonist activity at P2X7 receptor in human lymphocytes assessed as inhibition of ATP-induced Ba2+ influxMore data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium influxMore data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium influxMore data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMAssay Description:Activity at rat P2X7 receptor expressed in HEK cells assessed as effect on BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 15.8nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium influxMore data for this Ligand-Target Pair
Affinity DataIC50: 15.8nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 15.8nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 15.8nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair