Report error Found 4993 Enz. Inhib. hit(s) with Target = 'Metallo-beta-lactamase type 2'
Affinity DataKi: 90nMAssay Description:Competitive inhibition of Bacillus cereus 569/H/9 metallo-beta-lactamase Bc2 expressed in Escherichia coli GI724 cells using nitrocefin as substrate ...More data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of Aeromonas hydrophila cphAMore data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataKi: 490nMAssay Description:Mixed type inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells assessed as hydrolysis of c...More data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Inhibition of Aeromonas hydrophila cphAMore data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataKi: 580nMAssay Description:Time-dependent inhibition of wild type Klebsiella pneumoniae 6xHis-tagged metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21 (DE3)pLysSMore data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataKi: 630nMAssay Description:Mixed type inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells assessed as hydrolysis of c...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of Aeromonas hydrophila cphAMore data for this Ligand-Target Pair
Affinity DataKi: 1.28E+3nMAssay Description:Competitive inhibition of Bacillus cereus 569/H/9 metallo-beta-lactamase Bc2 expressed in Escherichia coli GI724 cells using nitrocefin as substrate ...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of Aeromonas hydrophila cphAMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of Aeromonas hydrophila cphAMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of Aeromonas hydrophila cphAMore data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataKi: 5.11E+3nMAssay Description:Non-competitive inhibition of NDM1 in Escherichia coli BL21 (DE3) using MEPM substrate incubated for 15 mins by UV spectroscopy based L-B plotMore data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataKi: 5.63E+3nMAssay Description:Non-competitive inhibition of NDM1 in Escherichia coli BL21 (DE3) using MEPM substrate incubated for 15 mins by UV spectroscopy based L-B plotMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:Inhibition of Aeromonas hydrophila cphAMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMAssay Description:Inhibition of Aeromonas hydrophila cphAMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMAssay Description:Competitive inhibition of Aeromonas hydrophila recombinant CphA expressed in Escherichia coli BL21(DE3) using meropenem as substrate by UV/Vis multi-...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 1.10E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as formation of 4-nitrothiophenolate at pH 7 using CENTA as chromogeni...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 1.20E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa metallo-beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) using CENTA as substrate by spe...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 1.30E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as formation of 4-nitrothiophenolate at pH 7 using CENTA as chromogeni...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of Aeromonas hydrophila cphAMore data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 1.40E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as formation of 4-nitrothiophenolate at pH 7 using CENTA as chromogeni...More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+4nMAssay Description:Inhibition of Aeromonas hydrophila cphAMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+4nMAssay Description:Inhibition of Aeromonas hydrophila cphAMore data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 1.50E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa metallo-beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) using CENTA as substrate by spe...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 1.60E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as formation of 4-nitrothiophenolate at pH 7 using CENTA as chromogeni...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataKi: 1.70E+4nMAssay Description:Inhibition of wild type N-terminal His6-tagged Klebsiella pneumoniae NDM-1 expressed in Escherichia coli BL21 assessed as inhibition constant using n...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as formation of 4-nitrothiophenolate at pH 7 using CENTA as chromogeni...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa metallo-beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) using CENTA as substrate by spe...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 1.90E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as formation of 4-nitrothiophenolate at pH 7 using CENTA as chromogeni...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 1.90E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa metallo-beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) using CENTA as substrate by spe...More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+4nMAssay Description:Inhibition of Aeromonas hydrophila cphAMore data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 2.90E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa metallo-beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) using CENTA as substrate by spe...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 3.30E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa metallo-beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) using CENTA as substrate by spe...More data for this Ligand-Target Pair
Affinity DataKi: >4.00E+4nMAssay Description:Inhibition of Aeromonas hydrophila cphAMore data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 4.10E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as formation of 4-nitrothiophenolate at pH 7 using CENTA as chromogeni...More data for this Ligand-Target Pair
Affinity DataKi: 5.20E+4nMAssay Description:Competitive inhibition of Aeromonas hydrophila recombinant CphA expressed in Escherichia coli BL21(DE3) using meropenem as substrate by UV/Vis multi-...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataKi: 5.50E+4nMAssay Description:Expression and Purification of Beta-Lactamases. For his tag KPC-2 beta-lactamase, bacteria were grown overnight at 30 C with shaking in 50 mL LB brot...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 7.50E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as formation of 4-nitrothiophenolate at pH 7 using CENTA as chromogeni...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataKi: 7.60E+4nMAssay Description:Time-dependent inhibition of wild type Klebsiella pneumoniae 6xHis-tagged metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21 (DE3)pLysS ...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataKi: 1.00E+5nMAssay Description:Expression and Purification of Beta-Lactamases. For his tag KPC-2 beta-lactamase, bacteria were grown overnight at 30 C with shaking in 50 mL LB brot...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataKi: 1.86E+5nMAssay Description:Competitive inhibition of His-tagged Klebsiella pneumoniae NDM-1 expressed in Escherichia coli BL21-AI cells using imipinem as substrateMore data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataKi: 1.86E+5nMAssay Description:Competitive inhibition of His-tagged Klebsiella pneumoniae NDM-1 expressed in Escherichia coli BL21-AI cells using imipinem as substrateMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of Aeromonas hydrophila cphAMore data for this Ligand-Target Pair
Affinity DataKi: 8.72E+5nMAssay Description:Competitive inhibition of Aeromonas hydrophila recombinant CphA expressed in Escherichia coli BL21(DE3) using meropenem as substrate by UV/Vis multi-...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: 2.30E+7nMAssay Description:Competitive inhibition of Bacteroides fragilis metallo-beta-lactamase CcrAMore data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataIC50: 0.00700nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataIC50: 0.00800nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataIC50: 0.0110nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair