Affinity DataKi: 11nM ΔG°: -47.3kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Evaluated for the dissociation constant for the inhibition of caspase-3More data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Evaluated for kinetic dissociation constant (kon) for the inhibition of caspase-7More data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Compound was tested for inhibitory activity against N-His (D381E) Interleukin -1 beta converting enzyme (resynthesized compound)More data for this Ligand-Target Pair
Affinity DataKi: 100nM ΔG°: -41.6kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 110nM ΔG°: -41.3kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 113nMAssay Description:Compound was tested for inhibitory activity against N-His (D381E) Interleukin -1 beta converting enzyme (resynthesized compound)More data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
Affinity DataKi: 290nM ΔG°: -38.8kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 410nM ΔG°: -37.9kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 430nM ΔG°: -37.8kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 440nM ΔG°: -37.7kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 450nM ΔG°: -37.7kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 490nM ΔG°: -37.5kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 620nM ΔG°: -36.9kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 880nM ΔG°: -36.0kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 900nM ΔG°: -35.9kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nM ΔG°: -35.6kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nM ΔG°: -35.4kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nM ΔG°: -34.4kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nM ΔG°: -34.4kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nM ΔG°: -34.0kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nM ΔG°: -33.5kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nM ΔG°: -33.4kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nM ΔG°: -32.8kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 3.10E+3nM ΔG°: -32.7kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 4.20E+3nM ΔG°: -31.9kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+3nMAssay Description:Compound was tested for binding affinity against N-His (D381E) Interleukin -1 beta converting enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 6.30E+3nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
Affinity DataKi: 6.80E+3nM ΔG°: -30.7kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 6.90E+3nM ΔG°: -30.6kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 7.20E+3nM ΔG°: -30.5kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 8.80E+3nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
Affinity DataKi: 9.40E+3nM ΔG°: -29.8kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+4nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+4nM ΔG°: -27.4kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+4nM ΔG°: -27.4kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+4nM ΔG°: -27.3kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataKi: 1.19E+5nM ΔG°: -23.3kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Dissociation constant for inhibition of caspase-1More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Dissociation constant for inhibition of caspase-1More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair