Compile Data Set for Download or QSAR
Report error Found 404 Enz. Inhib. hit(s) with all data for entry = 154
TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328121BDBM50328121(1-(pyridin-3-ylmethyl)-N-(4-(trifluoromethoxy)phen...)
Affinity DataIC50: 30nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328135BDBM50328135(N-(4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin...)
Affinity DataIC50: 40nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328138BDBM50328138((4-methylpiperazin-1-yl)(4-(4-(trifluoromethoxy)ph...)
Affinity DataIC50: 48nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196624BDBM196624(US9670214, TABLE 16.73)
Affinity DataIC50: 49nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328136BDBM50328136(6-(1H-pyrazol-4-yl)-N-(4-(trifluoromethoxy)phenyl)...)
Affinity DataIC50: 90nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328137BDBM50328137(6-(1-methyl-1H-pyrazol-4-yl)-N-(4-(trifluoromethox...)
Affinity DataIC50: 100nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196304BDBM196304(US9670214, TABLE 13.10)
Affinity DataIC50: 116nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328151BDBM50328151(4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-...)
Affinity DataIC50: 120nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328134BDBM50328134(2-(pyridin-3-ylmethyl)-N-(4-(trifluoromethoxy)phen...)
Affinity DataIC50: 122nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328160BDBM50328160(6-(1H-indol-4-yl)-N-(4-(trifluoromethoxy)phenyl)py...)
Affinity DataIC50: 140nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196573BDBM196573(US9670214, TABLE 16.22)
Affinity DataIC50: 140nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196600BDBM196600(US9670214, TABLE 16.49)
Affinity DataIC50: 150nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328158BDBM50328158(N-(4-(trifluoromethoxy)phenyl)-6-(1,3,5-trimethyl-...)
Affinity DataIC50: 150nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196173BDBM196173(US9670214, TABLE 10.16)
Affinity DataIC50: 160nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196599BDBM196599(US9670214, TABLE 16.48)
Affinity DataIC50: 160nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196197BDBM196197(US9670214, TABLE 10.29)
Affinity DataIC50: 160nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328124BDBM50328124(1-tert-butyl-N-(4-(trifluoromethoxy)phenyl)-1H-pyr...)
Affinity DataIC50: 160nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328162BDBM50328162(6-(1H-pyrrolo[2,3-b]pyridin-4-yl)-N-(4-(trifluorom...)
Affinity DataIC50: 166nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196613BDBM196613(US9670214, TABLE 16.62)
Affinity DataIC50: 170nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196601BDBM196601(US9670214, TABLE 16.50)
Affinity DataIC50: 190nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196238BDBM196238(US9670214, TABLE 10.41)
Affinity DataIC50: 194nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196252BDBM196252(US9670214, TABLE 10.47)
Affinity DataIC50: 195nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196621BDBM196621(US9670214, TABLE 16.70)
Affinity DataIC50: 196nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196556BDBM196556(US9670214, TABLE 16.5)
Affinity DataIC50: 210nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196196BDBM196196(US9670214, TABLE 10.28)
Affinity DataIC50: 210nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196402BDBM196402(US9670214, TABLE 14.1)
Affinity DataIC50: 214nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196555BDBM196555(US9670214, TABLE 16.4)
Affinity DataIC50: 220nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196582BDBM196582(US9670214, TABLE 16.31)
Affinity DataIC50: 240nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196590BDBM196590(US9670214, TABLE 16.39)
Affinity DataIC50: 240nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196277BDBM196277(US9670214, TABLE 12.19)
Affinity DataIC50: 245nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196248BDBM196248(US9670214, TABLE 10.46)
Affinity DataIC50: 246nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328198BDBM50328198(2-(4-(4-(Trifluoromethoxy)phenylamino)-1H-pyrazolo...)
Affinity DataIC50: 254nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196557BDBM196557(US9670214, TABLE 16.6)
Affinity DataIC50: 260nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196167BDBM196167(US9670214, TABLE 10.15)
Affinity DataIC50: 270nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196554BDBM196554(US9670214, TABLE 16.3)
Affinity DataIC50: 270nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328161BDBM50328161(6-(1H-indol-5-yl)-N-(4-(trifluoromethoxy)phenyl)py...)
Affinity DataIC50: 290nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196574BDBM196574(US9670214, TABLE 16.23)
Affinity DataIC50: 290nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328199BDBM50328199(1-ethyl-N-(4-(trifluoromethoxy)phenyl)-1H-pyrazolo...)
Affinity DataIC50: 300nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196175BDBM196175(US9670214, TABLE 10.18)
Affinity DataIC50: 308nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328184BDBM50328184((4-(4-(trifluoromethoxy)phenylamino)thieno[2,3-d]p...)
Affinity DataIC50: 330nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 195900BDBM195900(US9670214, TABLE 10.13)
Affinity DataIC50: 340nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328132BDBM50328132(2-(4-(4-(trifluoromethoxy)phenylamino)-2H-pyrazolo...)
Affinity DataIC50: 346nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196597BDBM196597(US9670214, TABLE 16.46)
Affinity DataIC50: 360nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328156BDBM50328156(6-(1-isobutyl-1H-pyrazol-4-yl)-N-(4-(trifluorometh...)
Affinity DataIC50: 360nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328194BDBM50328194(7-(2-morpholinoethyl)-N-(4-(trifluoromethoxy)pheny...)
Affinity DataIC50: 380nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase [T818I](Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196624BDBM196624(US9670214, TABLE 16.73)
Affinity DataIC50: 386nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 196226BDBM196226(US9670214, TABLE 10.36)
Affinity DataIC50: 397nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328201BDBM50328201(1-cyclohexyl-N-(4-(trifluoromethoxy)phenyl)-1H-pyr...)
Affinity DataIC50: 400nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 195891BDBM195891(US9670214, TABLE 10.4)
Affinity DataIC50: 400nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50328120BDBM50328120(1-benzyl-N-(4-(trifluoromethoxy)phenyl)-1H-pyrazol...)
Affinity DataIC50: 400nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

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