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Found 110 with Last Name = 'labby' and Initial = 'kj'
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50328814((+/-)-6-((4-(2-(3-fluorophenethylamino)ethoxy)pyrr...)
Affinity DataKi:  7nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50352520(CHEMBL1824857)
Affinity DataKi:  26nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli assessed as reduction in formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50429229(CHEMBL2332793)
Affinity DataKi:  46nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50429228(CHEMBL2332789)
Affinity DataKi:  70nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50429228(CHEMBL2332789)
Affinity DataKi:  71nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50352521(CHEMBL1824858)
Affinity DataKi:  77nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli assessed as reduction in formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50352518(CHEMBL1824855)
Affinity DataKi:  86nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli assessed as reduction in formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50352517(CHEMBL1614782)
Affinity DataKi:  110nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli assessed as reduction in formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetAcyl-protein thioesterase 2(Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi:  120nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 2 [P86Q](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi:  130nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50429230(CHEMBL2332791)
Affinity DataKi:  140nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50352516(CHEMBL1614783)
Affinity DataKi:  160nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli assessed as reduction in formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50429229(CHEMBL2332793)
Affinity DataKi:  170nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50352519(CHEMBL1824856)
Affinity DataKi:  170nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli assessed as reduction in formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50429231(CHEMBL2332792)
Affinity DataKi:  175nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50352522(CHEMBL1824859)
Affinity DataKi:  180nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli assessed as reduction in formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1 [I75L,S82A,Q83P,R149H,A150R,S151A](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi:  180nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 2 [M178L](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi:  200nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  280nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1 [I75L,S82A](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi:  280nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 1 [L176M](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  340nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1 [Q83P](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  370nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1 [I75L](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi:  370nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50366043(CHEMBL1956740 | US8927730, 3c)
Affinity DataKi:  390nMAssay Description:Inhibition of recombinant rat nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50366044(CHEMBL1956741 | US8927730, 3d)
Affinity DataKi:  400nMAssay Description:Inhibition of recombinant rat nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50366041(CHEMBL1956738 | US8927730, 3a)
Affinity DataKi:  410nMAssay Description:Inhibition of recombinant rat nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 2 [L78I,A85S,P86Q,H152R,R153A,A154S](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  430nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 2 [H152R](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi:  660nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50366042(CHEMBL1956739 | US8927730, 3b)
Affinity DataKi:  820nMAssay Description:Inhibition of recombinant rat nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50429228(CHEMBL2332789)
Affinity DataKi:  860nMAssay Description:Inhibition of mouse iNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 1 [I75L,S82A,Q83P](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi:  1.20E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 1 [I75L,S82A](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  1.20E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1 [I75L](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  2.20E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 2 [L78I,A85S,P86Q](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  3.40E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 2 [L78I](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  5.80E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50328814((+/-)-6-((4-(2-(3-fluorophenethylamino)ethoxy)pyrr...)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibition of mouse iNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 2 [L78I,A85S](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  6.20E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50429228(CHEMBL2332789)
Affinity DataKi:  7.60E+3nMAssay Description:Inhibition of mouse iNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50429230(CHEMBL2332791)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of mouse iNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 2 [L78I,A85S,P86Q,H152R,R153A,A154S](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 2 [L78I,A85S,P86Q](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 2 [L78I,A85S](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 2 [L78I](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1 [I75L,S82A,Q83P](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1 [Q83P](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 1 [L176M](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 1(Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 2 [H152R](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 2 [P86Q](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 1 [I75L,S82A,Q83P,R149H,A150R,S151A](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
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