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Compounds Sorted by Binding Targets per Compound

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304   310   315   323   339   369   370   371   372   373   374   375   376   377   378   380   381   383   384   
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429   443   447   515   
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Binding Targets
Enz. Inhib. Data
ITC Data
Alternate Compound Names
  • 5-HT1
  • 5-HT3A Serotonin Receptor
  • 5-HT5
  • 5-HT5B
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1B (5HT1B)
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 2C (5HT2C)
  • 5-hydroxytryptamine receptor 7
  • ADRA1B
  • ADRA2A
  • ADRA2C
  • Acetylcholinesterase
  • Adrenergic alpha1B
  • Adrenergic receptor
  • Adrenergic receptor alpha-2
  • Alpha adrenergic receptor 1A and 1B
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Alpha-1A adrenergic receptor
  • Alpha-1D adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Bile salt export pump
  • Calcium channel
  • Cerebral cortex alpha adrenergic receptor
  • Cytochrome P450 2D6 (2D6)
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • DNA topoisomerase I (Topo I)
  • Dopamine receptor
  • HTR1B
  • HTR1D
  • HTR1F
  • HTR2C
  • HTR5A
  • Imidazoline I1
  • POsterior Segregation family member (pos-1)
  • RecName: Full=Zinc finger protein mex-5
  • Serotonin (5-HT) receptor
  • Serotonin 1B/1D receptor
  • Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma non-opioid intracellular receptor 1
  • Sodium channel protein type I I alpha subunit
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • adrenergic Alpha1
  • adrenergic Alpha2
  • phosphatase Cdc25
304 Ki 18 IC50 8 Kd 3 EC50
  • (+)-yohimbine
  • (16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester
  • 17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester
  • CHEMBL15245
  • CORYNANTHINE
  • Johimbin
  • Quebrachin
  • RAUWOLSCINE
  • YOHIMBINE CHLORIDE
  • Yohimbin
  • Yohimbine
  • aphrodine
  • cid_8969
  • corynine
  • methyl 17alpha-hydroxyyohimban-16alpha-carboxylate
  • quebrachine
  • yohimbic acid methyl ester
  • 40S ribosomal protein S27
  • ALK tyrosine kinase receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Axin-1/Glycogen synthase kinase-3 beta
  • CDC7 and DBF4
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Ephrin type-A receptor 2
  • Epidermal growth factor receptor
  • Eukaryotic elongation factor 2 kinase
  • Fibroblast growth factor receptor 1
  • Focal adhesion kinase 1
  • Hepatocyte growth factor receptor
  • High affinity immunoglobulin gamma Fc receptor I
  • High affinity nerve growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • Insulin receptor
  • MAP kinase-activated protein kinase 2
  • MAP kinase-interacting serine/threonine-protein kinase 2
  • Mast/stem cell growth factor receptor Kit
  • Maternal embryonic leucine zipper kinase (MELK)
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 14
  • Mitotic checkpoint serine/threonine-protein kinase BUB1
  • Non-receptor tyrosine-protein kinase TYK2
  • PKC alpha and beta-2
  • Pancreatic endoplasmic reticulum kinase (PERK)
  • Proto-oncogene tyrosine-protein kinase ROS
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • RAC-alpha serine/threonine-protein kinase
  • Serine/threonine-protein kinase Chk1/2
  • Serine/threonine-protein kinase MST4
  • Serine/threonine-protein kinase NEK6
  • Serine/threonine-protein kinase NIM1
  • Serine/threonine-protein kinase PAK 4
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase haspin
  • Serine/threonine-protein kinase pim-1
  • Serine/threonine-protein kinase pim-2
  • Serine/threonine-protein kinase pim-3
  • Tyrosine kinase non-receptor protein 2
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase ZAP-70
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 3
  • [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
59 IC50
  • CHEMBL3297762
  • US9145418, 2
  • 3-phosphoinositide dependent protein kinase-1
  • ALK tyrosine kinase receptor
  • Activin receptor type-1
  • Aurora kinase A/Targeting protein for Xklp2
  • Axin-1/Glycogen synthase kinase-3 beta
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • Ephrin receptor
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Fibroblast growth factor receptor 2
  • Fibroblast growth factor receptor 3
  • Fibroblast growth factor receptor 4
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • MAP kinase-activated protein kinase 2
  • MAP kinase-activated protein kinase 5
  • MAP kinase-interacting serine/threonine-protein kinase 2
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase kinase kinase 8
  • Non-receptor tyrosine-protein kinase TYK2
  • Phosphatidylinositol 3-kinase catalytic subunit type 3
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Phosphatidylinositol 4-kinase beta
  • Platelet-derived growth factor receptor alpha
  • Protein kinase C alpha type
  • Protein kinase C theta type
  • Protein kinase N1
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • RAC-alpha serine/threonine-protein kinase
  • Receptor protein-tyrosine kinase erbB-4
  • Receptor tyrosine-protein kinase erbB-2
  • Rho-associated protein kinase 2
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase CSK
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase ZAP-70
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor UFO
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
62 IC50
  • CHEMBL3785951
  • 72 kDa type IV collagenase
  • Angiotensin-converting enzyme
  • Beta-secretase 1
  • Calpain1/2
  • Caspase-1
  • Caspase-10
  • Caspase-14
  • Caspase-2
  • Caspase-3
  • Caspase-4
  • Caspase-5
  • Caspase-6
  • Caspase-7
  • Caspase-8
  • Caspase-9
  • Cathepsin B
  • Cathepsin D
  • Cathepsin E
  • Cathepsin K
  • Cathepsin L2
  • Cathepsin S
  • Cathepsin Z
  • Chymase
  • Coagulation factor X
  • Coagulation factor XI
  • Collagenase 3
  • Dipeptidyl peptidase 4
  • Dipeptidyl peptidase 9
  • Dipeptidyl peptidase I
  • Dipeptidyl peptidase VIII
  • Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9)
  • Elastase
  • Interstitial collagenase
  • Kallikrein 4
  • Kallikrein 5
  • Kallikrein 8
  • Matrix metalloproteinase 10
  • Matrix metalloproteinase 11
  • Matrix metalloproteinase-12 (MMP12)
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Neutrophil collagenase
  • Papain
  • Plasma kallikrein
  • Plasminogen
  • Pro-cathepsin H
  • Prothrombin
  • Renin
  • Stromelysin-1
  • Trypsin
  • Tryptase
  • Urokinase-type plasminogen activator
  • Vitamin K-dependent protein C
75 IC50
  • CHEMBL567893
  • Grassystatin A